Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus

ACS Chemical Biology

Volumn 4, Issue 10, 2009, Pages 875-883

  Swoboda, Jonathan G ^a   Meredith, Timothy C ^a   Campbell, Jennifer ^a   Brown, Stephanie ^a   Suzuki, Takashi ^b   Bollenbach, Tobias ^a   Malhowski, Amy J ^c   Kishony, Roy ^a,d   Gilmore, Michael S ^b   Walker, Suzanne ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^c TUFTS MEDICAL CENTER   (United States)

^d HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1835F03; 7 CHLORO N,N DIETHYL 3 (PHENYLSULFONYL)[1,2,3]TRIAZOLO[1,5 A]QUINOLIN 5 AMINE; ANTIBIOTIC AGENT; POLYMER; TEICHOIC ACID; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; BACTERIAL CELL WALL; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL VIABILITY; BIOSYNTHESIS; CELL SURFACE; DRUG MECHANISM; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; SMALL MOLECULE LIBRARIES; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TEICHOIC ACIDS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 70350153882     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb900151k     Document Type: Article

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