Increased expression of matrix metalloproteinases mediates thromboxane A 2-induced invasion in lung cancer cells

Current Cancer Drug Targets

Volumn 12, Issue 6, 2012, Pages 703-715

  Li, Xiuling ^a   Tai, Hsin Hsiung ^a  

^a University of Kentucky   (United States)

Author keywords

Invasion; Matrix metalloproteinase; Metastasis; Signal transduction; Thromboxane A 2 receptor

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; GELATINASE B; ILOMASTAT; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; SMALL INTERFERING RNA; STROMELYSIN; STROMELYSIN 2; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR;

ARTICLE; CANCER CELL; CANCER INVASION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG ADENOCARCINOMA; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

ADENOCARCINOMA; BICYCLO COMPOUNDS, HETEROCYCLIC; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CELL MOVEMENT; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS, UNSATURATED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 10; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; NEOPLASM INVASIVENESS; PROTEASE INHIBITORS; PROTEIN KINASE C; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; THROMBOXANE A2; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; UP-REGULATION;

EID: 84862609568     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/156800912801784884     Document Type: Article

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