Activation of thromboxane receptor α induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells

Biochemical Pharmacology

Volumn 74, Issue 5, 2007, Pages 787-800

  Wei, Jingyan ^a,b   Yan, Weili ^a   Li, Xiuling ^a   Chang, Wen Chang ^c   Tai, Hsin Hsiung ^a  

^a University of Kentucky   (United States)

^b JILIN UNIVERSITY   (China)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Cyclooxygenase 2; Gene expression; Prostaglandins; Signal transduction; Thromboxane receptor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; CELECOXIB; CURCUMIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; DAZOXIBEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROSTAGLANDIN E2; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; THROMBOXANE RECEPTOR; UO 126; WORTMANNIN;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG ACTIVATION; DRUG EFFECT; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PHOSPHORYLATION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL LINE, TUMOR; CYCLOOXYGENASE 2; ENZYME INDUCTION; FATTY ACIDS, UNSATURATED; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; PROTEIN ISOFORMS; RECEPTORS, THROMBOXANE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 34447629368     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.06.008     Document Type: Article

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