메뉴 건너뛰기




Volumn 366, Issue 1, 2013, Pages 90-98

Dickkopf-1 inhibits thyroid cancer cell survival and migration through regulation of β-catenin/E-cadherin signaling

Author keywords

Catenin; Dkk 1; E cadherin; Papillary thyroid cancer; Wnt

Indexed keywords

BETA CATENIN; BROXURIDINE; DICKKOPF 1 PROTEIN; MESSENGER RNA; RECOMBINANT DICKKOPF 1 PROTEIN; RECOMBINANT PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84872492600     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.12.007     Document Type: Article
Times cited : (32)

References (55)
  • 1
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • Bafico A., Liu G., Yaniv A., Gazit A., Aaronson S.A. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol. 2001, 3:683-686.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 2
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
    • Bafico A., Liu G., Goldin L., Harris V., Aaronson S.A. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004, 6:497-506.
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Bafico, A.1    Liu, G.2    Goldin, L.3    Harris, V.4    Aaronson, S.A.5
  • 3
    • 0033777043 scopus 로고    scopus 로고
    • Catenins, Wnt signaling and cancer
    • Barker N., Clevers H. Catenins, Wnt signaling and cancer. Bioessays 2000, 22:961-965.
    • (2000) Bioessays , vol.22 , pp. 961-965
    • Barker, N.1    Clevers, H.2
  • 4
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz M., Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000, 103:311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 6
    • 0035866397 scopus 로고    scopus 로고
    • Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription
    • Bonvini P., An W.G., Rosolen A., Nguyen P., Trepel J., Garcia de Herreros A., Dunach M., Neckers L.M. Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription. Cancer Res. 2001, 61:1671-1677.
    • (2001) Cancer Res. , vol.61 , pp. 1671-1677
    • Bonvini, P.1    An, W.G.2    Rosolen, A.3    Nguyen, P.4    Trepel, J.5    Garcia de Herreros, A.6    Dunach, M.7    Neckers, L.M.8
  • 9
    • 58249112736 scopus 로고    scopus 로고
    • RET/PTC1-driven neoplastic transformation and proinvasive phenotype of human thyrocytes involve Met induction and beta-catenin nuclear translocation
    • Cassinelli G., Favini E., Degl'Innocenti D., Salvi A., De Petro G., Pierotti M.A., Zunino F., Borrello M.G., Lanzi C. RET/PTC1-driven neoplastic transformation and proinvasive phenotype of human thyrocytes involve Met induction and beta-catenin nuclear translocation. Neoplasia 2009, 11:10-21.
    • (2009) Neoplasia , vol.11 , pp. 10-21
    • Cassinelli, G.1    Favini, E.2    Degl'Innocenti, D.3    Salvi, A.4    De Petro, G.5    Pierotti, M.A.6    Zunino, F.7    Borrello, M.G.8    Lanzi, C.9
  • 10
    • 62449290428 scopus 로고    scopus 로고
    • The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation
    • Castellone M.D., De Falco V., Rao D.M., Bellelli R., Muthu M., Basolo F., Fusco A., Gutkind J.S., Santoro M. The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation. Cancer Res. 2009, 69:1867-1876.
    • (2009) Cancer Res. , vol.69 , pp. 1867-1876
    • Castellone, M.D.1    De Falco, V.2    Rao, D.M.3    Bellelli, R.4    Muthu, M.5    Basolo, F.6    Fusco, A.7    Gutkind, J.S.8    Santoro, M.9
  • 11
    • 0035408007 scopus 로고    scopus 로고
    • FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak
    • Ciruna B., Rossant J. FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev. Cell 2001, 1:37-49.
    • (2001) Dev. Cell , vol.1 , pp. 37-49
    • Ciruna, B.1    Rossant, J.2
  • 12
    • 0024425390 scopus 로고
    • A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
    • Civitareale D., Lonigro R., Sinclair A.J., Di Lauro R. A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter. EMBO J. 1989, 8:2537-2542.
    • (1989) EMBO J. , vol.8 , pp. 2537-2542
    • Civitareale, D.1    Lonigro, R.2    Sinclair, A.J.3    Di Lauro, R.4
  • 13
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H., Nusse R. Wnt/beta-catenin signaling and disease. Cell 2012, 149:1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 14
    • 0036120562 scopus 로고    scopus 로고
    • The cadherin-catenin adhesion system in signaling and cancer
    • Conacci-Sorrell M., Zhurinsky J., Ben-Ze'ev A. The cadherin-catenin adhesion system in signaling and cancer. J. Clin. Invest. 2002, 109:987-991.
    • (2002) J. Clin. Invest. , vol.109 , pp. 987-991
    • Conacci-Sorrell, M.1    Zhurinsky, J.2    Ben-Ze'ev, A.3
  • 15
    • 0033516577 scopus 로고    scopus 로고
    • Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling
    • Fedi P., Bafico A., Nieto Soria A., Burgess W.H., Miki T., Bottaro D.P., Kraus M.H., Aaronson S.A. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J. Biol. Chem. 1999, 274:19465-19472.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19465-19472
    • Fedi, P.1    Bafico, A.2    Nieto Soria, A.3    Burgess, W.H.4    Miki, T.5    Bottaro, D.P.6    Kraus, M.H.7    Aaronson, S.A.8
  • 17
    • 0035108299 scopus 로고    scopus 로고
    • Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis
    • Garcia-Rostan G., Camp R.L., Herrero A., Carcangiu M.L., Rimm D.L., Tallini G. Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis. Am. J. Pathol. 2001, 158:987-996.
    • (2001) Am. J. Pathol. , vol.158 , pp. 987-996
    • Garcia-Rostan, G.1    Camp, R.L.2    Herrero, A.3    Carcangiu, M.L.4    Rimm, D.L.5    Tallini, G.6
  • 18
    • 0032567078 scopus 로고    scopus 로고
    • De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • Gat U., DasGupta R., Degenstein L., Fuchs E. De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 1998, 95:605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 19
    • 79960626850 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells
    • Gilbert-Sirieix M., Makoukji J., Kimura S., Talbot M., Caillou B., Massaad C., Massaad-Massade L. Wnt/beta-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells. PLoS ONE 2011, 6:e22280.
    • (2011) PLoS ONE , vol.6
    • Gilbert-Sirieix, M.1    Makoukji, J.2    Kimura, S.3    Talbot, M.4    Caillou, B.5    Massaad, C.6    Massaad-Massade, L.7
  • 22
    • 0032493042 scopus 로고    scopus 로고
    • Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin
    • Itoh K., Krupnik V.E., Sokol S.Y. Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin. Curr. Biol. 1998, 8:591-594.
    • (1998) Curr. Biol. , vol.8 , pp. 591-594
    • Itoh, K.1    Krupnik, V.E.2    Sokol, S.Y.3
  • 23
    • 73449088791 scopus 로고    scopus 로고
    • Clinical significance of serum DKK-1 in patients with gynecological cancer
    • Jiang T., Wang S., Huang L., Zhang S. Clinical significance of serum DKK-1 in patients with gynecological cancer. Int. J. Gynecol. Cancer 2009, 19:1177-1181.
    • (2009) Int. J. Gynecol. Cancer , vol.19 , pp. 1177-1181
    • Jiang, T.1    Wang, S.2    Huang, L.3    Zhang, S.4
  • 24
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura E.T., Nikiforova M.N., Zhu Z., Knauf J.A., Nikiforov Y.E., Fagin J.A. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res. 2003, 63:1454-1457.
    • (2003) Cancer Res. , vol.63 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 29
    • 0001331879 scopus 로고    scopus 로고
    • Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics
    • Le T.L., Yap A.S., Stow J.L. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J. Cell. Biol. 1999, 146:219-232.
    • (1999) J. Cell. Biol. , vol.146 , pp. 219-232
    • Le, T.L.1    Yap, A.S.2    Stow, J.L.3
  • 31
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • Mao B., Wu W., Li Y., Hoppe D., Stannek P., Glinka A., Niehrs C. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 2001, 411:321-325.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6    Niehrs, C.7
  • 32
    • 1642545618 scopus 로고    scopus 로고
    • A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation
    • Mikheev A.M., Mikheeva S.A., Liu B., Cohen P., Zarbl H. A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation. Carcinogenesis 2004, 25:47-59.
    • (2004) Carcinogenesis , vol.25 , pp. 47-59
    • Mikheev, A.M.1    Mikheeva, S.A.2    Liu, B.3    Cohen, P.4    Zarbl, H.5
  • 34
  • 35
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson W.J., Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004, 303:1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 36
    • 0034145199 scopus 로고    scopus 로고
    • Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas
    • Ordonez N.G. Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas. Adv. Anat. Pathol. 2000, 7:123-127.
    • (2000) Adv. Anat. Pathol. , vol.7 , pp. 123-127
    • Ordonez, N.G.1
  • 39
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus
    • Peifer M., Polakis P. Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science 2000, 287:1606-1609.
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 40
    • 0037378505 scopus 로고    scopus 로고
    • P120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction
    • Piedra J., Miravet S., Castano J., Palmer H.G., Heisterkamp N., Garcia de Herreros A., Dunach M. P120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. Mol. Cell. Biol. 2003, 23:2287-2297.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2287-2297
    • Piedra, J.1    Miravet, S.2    Castano, J.3    Palmer, H.G.4    Heisterkamp, N.5    Garcia de Herreros, A.6    Dunach, M.7
  • 41
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev. 2000, 14:1837-1851.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 42
    • 0035369302 scopus 로고    scopus 로고
    • More than one way to skin a catenin
    • Polakis P. More than one way to skin a catenin. Cell 2001, 105:563-566.
    • (2001) Cell , vol.105 , pp. 563-566
    • Polakis, P.1
  • 43
    • 35348998631 scopus 로고    scopus 로고
    • Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells
    • Qin X., Zhang H., Zhou X., Wang C., Zhang X., Ye L. Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells. Transl. Res. 2007, 150:281-294.
    • (2007) Transl. Res. , vol.150 , pp. 281-294
    • Qin, X.1    Zhang, H.2    Zhou, X.3    Wang, C.4    Zhang, X.5    Ye, L.6
  • 48
    • 85047699343 scopus 로고    scopus 로고
    • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
    • Shou J., Ali-Osman F., Multani A.S., Pathak S., Fedi P., Srivenugopal K.S. Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. Oncogene 2002, 21:878-889.
    • (2002) Oncogene , vol.21 , pp. 878-889
    • Shou, J.1    Ali-Osman, F.2    Multani, A.S.3    Pathak, S.4    Fedi, P.5    Srivenugopal, K.S.6
  • 50
    • 77449159263 scopus 로고    scopus 로고
    • Dickkopf-1 is overexpressed in human pancreatic ductal adenocarcinoma cells and is involved in invasive growth
    • Takahashi N., Fukushima T., Yorita K., Tanaka H., Chijiiwa K., Kataoka H. Dickkopf-1 is overexpressed in human pancreatic ductal adenocarcinoma cells and is involved in invasive growth. Int. J. Cancer. 2010, 126:1611-1620.
    • (2010) Int. J. Cancer. , vol.126 , pp. 1611-1620
    • Takahashi, N.1    Fukushima, T.2    Yorita, K.3    Tanaka, H.4    Chijiiwa, K.5    Kataoka, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.