-
1
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 2007, 128:693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
2
-
-
69549124552
-
Proteome-wide prediction of acetylation substrates
-
Basu A., Rose K.L., Zhang J., Beavis R.C., Ueberheide B., Garcia B.A., Chait B., Zhao Y., Hunt D.F., Segal E., Allis C.D., Hake S.B. Proteome-wide prediction of acetylation substrates. Proc. Natl. Acad. Sci. USA 2009, 106:13785-13790.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13785-13790
-
-
Basu, A.1
Rose, K.L.2
Zhang, J.3
Beavis, R.C.4
Ueberheide, B.5
Garcia, B.A.6
Chait, B.7
Zhao, Y.8
Hunt, D.F.9
Segal, E.10
Allis, C.D.11
Hake, S.B.12
-
3
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 2009, 325:834-840.
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
Olsen, J.V.7
Mann, M.8
-
4
-
-
79551500427
-
Targeted large-scale analysis of protein acetylation
-
Mischerikow N., Heck A.J. Targeted large-scale analysis of protein acetylation. Proteomics 2011, 11:571-589.
-
(2011)
Proteomics
, vol.11
, pp. 571-589
-
-
Mischerikow, N.1
Heck, A.J.2
-
5
-
-
0033000990
-
Histone acetylases and deacetylases in cell proliferation
-
Kouzarides T. Histone acetylases and deacetylases in cell proliferation. Curr. Opin. Genet. Dev. 1999, 9:40-48.
-
(1999)
Curr. Opin. Genet. Dev.
, vol.9
, pp. 40-48
-
-
Kouzarides, T.1
-
6
-
-
0036261826
-
The diversity of acetylated proteins
-
reviews0006
-
Polevoda B., Sherman F. The diversity of acetylated proteins. Genome Biol. 2002, 3. reviews0006.
-
(2002)
Genome Biol.
, vol.3
-
-
Polevoda, B.1
Sherman, F.2
-
7
-
-
1842684989
-
HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization
-
Serrador J.M., Cabrero J.R., Sancho D., Mittelbrunn M., Urzainqui A., Sanchez-Madrid F. HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization. Immunity 2004, 20:417-428.
-
(2004)
Immunity
, vol.20
, pp. 417-428
-
-
Serrador, J.M.1
Cabrero, J.R.2
Sancho, D.3
Mittelbrunn, M.4
Urzainqui, A.5
Sanchez-Madrid, F.6
-
8
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
Zhao S., Xu W., Jiang W.Q., Yu W., Lin Y., Zhang T.F., Yao J., Zhou L., Zeng Y.X., Li H., Li Y.X., Shi J., An W.L., Hancock S.M., He F.C., Qin L.X., Chin J., Yang P.Y., Chen X., Lei Q.Y., Xiong Y., Guan K.L. Regulation of cellular metabolism by protein lysine acetylation. Science 2010, 327:1000-1004.
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.Q.3
Yu, W.4
Lin, Y.5
Zhang, T.F.6
Yao, J.7
Zhou, L.8
Zeng, Y.X.9
Li, H.10
Li, Y.X.11
Shi, J.12
An, W.L.13
Hancock, S.M.14
He, F.C.15
Qin, L.X.16
Chin, J.17
Yang, P.Y.18
Chen, X.19
Lei, Q.Y.20
Xiong, Y.21
Guan, K.L.22
more..
-
9
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
Hubbert C., Guardiola A., Shao R., Kawaguchi Y., Ito A., Nixon A., Yoshida M., Wang X.F., Yao T.P. HDAC6 is a microtubule-associated deacetylase. Nature 2002, 417:455-458.
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
Guardiola, A.2
Shao, R.3
Kawaguchi, Y.4
Ito, A.5
Nixon, A.6
Yoshida, M.7
Wang, X.F.8
Yao, T.P.9
-
10
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Kawaguchi Y., Kovacs J.J., McLaurin A., Vance J.M., Ito A., Yao T.P. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 2003, 115:727-738.
-
(2003)
Cell
, vol.115
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.P.6
-
11
-
-
0037108963
-
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes
-
Hook S.S., Orian A., Cowley S.M., Eisenman R.N. Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes. Proc. Natl. Acad. Sci. USA 2002, 99:13425-13430.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13425-13430
-
-
Hook, S.S.1
Orian, A.2
Cowley, S.M.3
Eisenman, R.N.4
-
12
-
-
77649337122
-
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
-
Lee J.Y., Koga H., Kawaguchi Y., Tang W., Wong E., Gao Y.S., Pandey U.B., Kaushik S., Tresse E., Lu J., Taylor J.P., Cuervo A.M., Yao T.P. HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J. 2010, 29:969-980.
-
(2010)
EMBO J.
, vol.29
, pp. 969-980
-
-
Lee, J.Y.1
Koga, H.2
Kawaguchi, Y.3
Tang, W.4
Wong, E.5
Gao, Y.S.6
Pandey, U.B.7
Kaushik, S.8
Tresse, E.9
Lu, J.10
Taylor, J.P.11
Cuervo, A.M.12
Yao, T.P.13
-
13
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
-
Iwata A., Riley B.E., Johnston J.A., Kopito R.R. HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J. Biol. Chem. 2005, 280:40282-40292.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
14
-
-
77954208049
-
Drosophila histone deacetylase 6 protects dopaminergic neurons against α-synuclein toxicity by promoting inclusion formation
-
Du G., Liu X., Chen X., Song M., Yan Y., Jiao R., Wang C.C. Drosophila histone deacetylase 6 protects dopaminergic neurons against α-synuclein toxicity by promoting inclusion formation. Mol. Biol. Cell 2010, 21:2128-2137.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2128-2137
-
-
Du, G.1
Liu, X.2
Chen, X.3
Song, M.4
Yan, Y.5
Jiao, R.6
Wang, C.C.7
-
15
-
-
82055164435
-
Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions
-
Miki Y., Mori F., Tanji K., Kakita A., Takahashi H., Wakabayashi K. Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions. Neuropathology 2011, 31:561-568.
-
(2011)
Neuropathology
, vol.31
, pp. 561-568
-
-
Miki, Y.1
Mori, F.2
Tanji, K.3
Kakita, A.4
Takahashi, H.5
Wakabayashi, K.6
-
16
-
-
84866444893
-
Immunohistochemical localization of aggresomal proteins in glial cytoplasmic inclusions in multiple system atrophy
-
Chiba Y., Takei S., Kawamura N., Kawaguchi Y., Sasaki K., Hasegawa-Ishii S., Furukawa A., Hosokawa M., Shimada A. Immunohistochemical localization of aggresomal proteins in glial cytoplasmic inclusions in multiple system atrophy. Neuropathol. Appl. Neurobiol. 2012, 38:559-571.
-
(2012)
Neuropathol. Appl. Neurobiol.
, vol.38
, pp. 559-571
-
-
Chiba, Y.1
Takei, S.2
Kawamura, N.3
Kawaguchi, Y.4
Sasaki, K.5
Hasegawa-Ishii, S.6
Furukawa, A.7
Hosokawa, M.8
Shimada, A.9
-
17
-
-
33144489150
-
Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium
-
Consortium on DLB
-
McKeith I.G., Dickson D.W., Lowe J., Emre M., O'Brien J.T., Feldman H., Cummings J., Duda J.E., Lippa C., Perry E.K., Aarsland D., Arai H., Ballard C.G., Boeve B., Burn D.J., Costa D., Del Ser T., Dubois B., Galasko D., Gauthier S., Goetz C.G., Gomez-Tortosa E., Halliday G., Hansen L.A., Hardy J., Iwatsubo T., Kalaria R.N., Kaufer D., Kenny R.A., Korczyn A., Kosaka K., Lee V.M., Lees A., Litvan I., Londos E., Lopez O.L., Minoshima S., Mizuno Y., Molina J.A., Mukaetova-Ladinska E.B., Pasquier F., Perry R.H., Schulz J.B., Trojanowski J.Q., Yamada M., Consortium on DLB Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium. Neurology 2005, 65:1863-1872.
-
(2005)
Neurology
, vol.65
, pp. 1863-1872
-
-
McKeith, I.G.1
Dickson, D.W.2
Lowe, J.3
Emre, M.4
O'Brien, J.T.5
Feldman, H.6
Cummings, J.7
Duda, J.E.8
Lippa, C.9
Perry, E.K.10
Aarsland, D.11
Arai, H.12
Ballard, C.G.13
Boeve, B.14
Burn, D.J.15
Costa, D.16
Del Ser, T.17
Dubois, B.18
Galasko, D.19
Gauthier, S.20
Goetz, C.G.21
Gomez-Tortosa, E.22
Halliday, G.23
Hansen, L.A.24
Hardy, J.25
Iwatsubo, T.26
Kalaria, R.N.27
Kaufer, D.28
Kenny, R.A.29
Korczyn, A.30
Kosaka, K.31
Lee, V.M.32
Lees, A.33
Litvan, I.34
Londos, E.35
Lopez, O.L.36
Minoshima, S.37
Mizuno, Y.38
Molina, J.A.39
Mukaetova-Ladinska, E.B.40
Pasquier, F.41
Perry, R.H.42
Schulz, J.B.43
Trojanowski, J.Q.44
Yamada, M.45
more..
-
18
-
-
79959599081
-
A harmonized classification system for FTLD-TDP pathology
-
Mackenzie I.R., Neumann M., Baborie A., Sampathu D.M., Du Plessis D., Jaros E., Perry R.H., Trojanowski J.Q., Mann D.M., Lee V.M. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol. 2011, 122:111-113.
-
(2011)
Acta Neuropathol.
, vol.122
, pp. 111-113
-
-
Mackenzie, I.R.1
Neumann, M.2
Baborie, A.3
Sampathu, D.M.4
Du Plessis, D.5
Jaros, E.6
Perry, R.H.7
Trojanowski, J.Q.8
Mann, D.M.9
Lee, V.M.10
-
19
-
-
35948994645
-
Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
-
Neuropathology Working Group on MSA
-
Trojanowski J.Q., Revesz T., Neuropathology Working Group on MSA Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy. Neuropathol. Appl. Neurobiol. 2007, 33:615-620.
-
(2007)
Neuropathol. Appl. Neurobiol.
, vol.33
, pp. 615-620
-
-
Trojanowski, J.Q.1
Revesz, T.2
-
20
-
-
84864831305
-
P62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions
-
Tanji K., Zhang H.X., Mori F., Kakita A., Takahashi H., Wakabayashi K. P62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions. J. Neurosci. Res. 2012, 90:2034-2042.
-
(2012)
J. Neurosci. Res.
, vol.90
, pp. 2034-2042
-
-
Tanji, K.1
Zhang, H.X.2
Mori, F.3
Kakita, A.4
Takahashi, H.5
Wakabayashi, K.6
-
21
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
22
-
-
33846930889
-
Microtubule deacetylase, SirT2 and HDAC6, in the nervous system
-
Southwood C.M., Peppi M., Dryden S., Tainsky M.A., Gow A. Microtubule deacetylase, SirT2 and HDAC6, in the nervous system. Neurochem. Res. 2007, 32:187-195.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 187-195
-
-
Southwood, C.M.1
Peppi, M.2
Dryden, S.3
Tainsky, M.A.4
Gow, A.5
-
23
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey U.B., Nie Z., Batlevi Y., McCray B.A., Ritson G.P., Nedelsky N.B., Schwartz S.L., DiProspero N.A., Knight M.A., Schuldiner O., Padmanabhan R., Hild M., Berry D.L., Garza D., Hubbert C.C., Yao T.P., Baehrecke E.H., Taylor J.P. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 2007, 447:859-863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
DiProspero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
24
-
-
78149469728
-
Chaperone-mediated autophagy markers in Parkinson disease brains
-
Alvarez-Erviti L., Rodriguez-Oroz M.C., Cooper J.M., Caballero C., Ferrer I., Obeso J.A., Schapira A.H. Chaperone-mediated autophagy markers in Parkinson disease brains. Arch. Neurol. 2010, 67:1464-1472.
-
(2010)
Arch. Neurol.
, vol.67
, pp. 1464-1472
-
-
Alvarez-Erviti, L.1
Rodriguez-Oroz, M.C.2
Cooper, J.M.3
Caballero, C.4
Ferrer, I.5
Obeso, J.A.6
Schapira, A.H.7
-
25
-
-
77949504405
-
Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of α-synucleinopathy
-
Crews L., Spencer B., Desplats P., Patrick C., Paulino A., Rockenstein E., Hansen L., Adame A., Galasko D., Masliah E. Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of α-synucleinopathy. PLoS One 2010, 5:e9313.
-
(2010)
PLoS One
, vol.5
-
-
Crews, L.1
Spencer, B.2
Desplats, P.3
Patrick, C.4
Paulino, A.5
Rockenstein, E.6
Hansen, L.7
Adame, A.8
Galasko, D.9
Masliah, E.10
-
26
-
-
77956855813
-
Pathogenic lysosomal depletion in Parkinson's disease
-
Dehay B., Bove J., Rodriguez-Muela N., Perier C., Recasens A., Boya P., Vila M. Pathogenic lysosomal depletion in Parkinson's disease. J. Neurosci. 2010, 30:12535-12544.
-
(2010)
J. Neurosci.
, vol.30
, pp. 12535-12544
-
-
Dehay, B.1
Bove, J.2
Rodriguez-Muela, N.3
Perier, C.4
Recasens, A.5
Boya, P.6
Vila, M.7
-
27
-
-
79953167820
-
Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies
-
Higashi S., Moore D.J., Minegishi M., Kasanuki K., Fujishiro H., Kabuta T., Togo T., Katsuse O., Uchikado H., Furukawa Y., Hino H., Kosaka K., Sato K., Arai H., Wada K., Iseki E. Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies. J. Neuropathol. Exp. Neurol. 2011, 70:264-280.
-
(2011)
J. Neuropathol. Exp. Neurol.
, vol.70
, pp. 264-280
-
-
Higashi, S.1
Moore, D.J.2
Minegishi, M.3
Kasanuki, K.4
Fujishiro, H.5
Kabuta, T.6
Togo, T.7
Katsuse, O.8
Uchikado, H.9
Furukawa, Y.10
Hino, H.11
Kosaka, K.12
Sato, K.13
Arai, H.14
Wada, K.15
Iseki, E.16
-
28
-
-
79960226234
-
Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease
-
Tanji K., Mori F., Kakita A., Takahashi H., Wakabayashi K. Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease. Neurobiol. Dis. 2011, 43:690-697.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 690-697
-
-
Tanji, K.1
Mori, F.2
Kakita, A.3
Takahashi, H.4
Wakabayashi, K.5
-
29
-
-
84863877366
-
Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes
-
Schwarz L., Goldbaum O., Bergmann M., Probst-Cousin S., Richter-Landsberg C. Involvement of macroautophagy in multiple system atrophy and protein aggregate formation in oligodendrocytes. J. Mol. Neurosci. 2012, 47:256-266.
-
(2012)
J. Mol. Neurosci.
, vol.47
, pp. 256-266
-
-
Schwarz, L.1
Goldbaum, O.2
Bergmann, M.3
Probst-Cousin, S.4
Richter-Landsberg, C.5
-
30
-
-
49549083278
-
Histone deacetylase 6 interacts with the microtubule-associated protein tau
-
Ding H., Dolan P.J., Johnson G.V. Histone deacetylase 6 interacts with the microtubule-associated protein tau. J. Neurochem. 2008, 106:2119-2130.
-
(2008)
J. Neurochem.
, vol.106
, pp. 2119-2130
-
-
Ding, H.1
Dolan, P.J.2
Johnson, G.V.3
-
31
-
-
77958604956
-
Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA
-
Kim S.H., Shanware N.P., Bowler M.J., Tibbetts R.S. Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA. J. Biol. Chem. 2010, 285:34097-34105.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34097-34105
-
-
Kim, S.H.1
Shanware, N.P.2
Bowler, M.J.3
Tibbetts, R.S.4
-
32
-
-
80052136588
-
TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6
-
Fiesel F.C., Schurr C., Weber S.S., Kahle P.J. TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6. Mol. Neurodegener. 2011, 6:64.
-
(2011)
Mol. Neurodegener.
, vol.6
, pp. 64
-
-
Fiesel, F.C.1
Schurr, C.2
Weber, S.S.3
Kahle, P.J.4
-
33
-
-
77958012134
-
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
-
Chiang P.M., Ling J., Jeong Y.H., Price D.L., Aja S.M., Wong P.C. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc. Natl. Acad. Sci. USA 2010, 107:16320-16324.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16320-16324
-
-
Chiang, P.M.1
Ling, J.2
Jeong, Y.H.3
Price, D.L.4
Aja, S.M.5
Wong, P.C.6
-
34
-
-
77956199371
-
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice
-
Xu Y.F., Gendron T.F., Zhang Y.J., Lin W.L., D'Alton S., Sheng H., Casey M.C., Tong J., Knight J., Yu X., Rademakers R., Boylan K., Hutton M., McGowan E., Dickson D.W., Lewis J., Petrucelli L. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J. Neurosci. 2010, 30:10851-10859.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10851-10859
-
-
Xu, Y.F.1
Gendron, T.F.2
Zhang, Y.J.3
Lin, W.L.4
D'Alton, S.5
Sheng, H.6
Casey, M.C.7
Tong, J.8
Knight, J.9
Yu, X.10
Rademakers, R.11
Boylan, K.12
Hutton, M.13
McGowan, E.14
Dickson, D.W.15
Lewis, J.16
Petrucelli, L.17
-
35
-
-
79551523377
-
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
-
Igaz L.M., Kwong L.K., Lee E.B., Chen-Plotkin A., Swanson E., Unger T., Malunda J., Xu Y., Winton M.J., Trojanowski J.Q., Lee V.M. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. J. Clin. Invest. 2011, 121:726-738.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 726-738
-
-
Igaz, L.M.1
Kwong, L.K.2
Lee, E.B.3
Chen-Plotkin, A.4
Swanson, E.5
Unger, T.6
Malunda, J.7
Xu, Y.8
Winton, M.J.9
Trojanowski, J.Q.10
Lee, V.M.11
|