The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: Similarities and distinct actions from soy isoflavone genistein

Genes and Nutrition

Volumn 8, Issue 1, 2013, Pages 79-90

  Pabona, John Mark P ^a,b   Dave, Bhuvanesh ^b,c   Su, Ying ^b,d   Montales, Maria Theresa E ^a,b   De Lumen, Ben O ^e   De Mejia, Elvira G ^f   Rahal, Omar M ^a,b   Simmen, Rosalia C M ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

^c HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Apoptosis; Breast cancer; Genistein; Lunasin; Mammary epithelial; PTEN; Soy

Indexed keywords

BETA CATENIN; GENISTEIN; HERBACEOUS AGENT; LUNASIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; SOYBEAN PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER STEM CELL; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN LOCALIZATION; SOYBEAN; TREATMENT RESPONSE;

GLYCINE MAX;

EID: 84872402990     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-012-0307-5     Document Type: Article

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