Chemopreventive property of a soybean peptide (Lunasin) that binds to deacetylated histones and inhibits acetylation

Cancer Research

Volumn 61, Issue 20, 2001, Pages 7473-7478

  Galvez, A F ^a   Chen, N ^a   Macasieb, J ^a   De Lumen, B O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HISTONE DEACETYLASE INHIBITOR; LUNASIN; PEPTIDE HORMONE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN MCF 7; CELL TRANSFORMATION; CHEMICAL CARCINOGENESIS; CHEMOPROPHYLAXIS; CHROMATIN; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SKIN CANCER; SOYBEAN;

ACETYLATION; ADENOVIRUS E1A PROTEINS; AMINO ACID SEQUENCE; ANIMALS; ANTICARCINOGENIC AGENTS; BREAST NEOPLASMS; BUTYRATES; CELL ADHESION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; FIBROBLASTS; HISTONE DEACETYLASES; HISTONES; HUMANS; MICE; MICE, INBRED C3H; MICE, INBRED SENCAR; PLANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SKIN NEOPLASMS; SOYBEAN PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035887086     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Dietary isoflavones: Biological effects and relevance to human health
2. Soy intake and cancer risk: Review of the in vivo and in vitro data
3. The role of soy products in reducing risk of cancer
4. The evidence for soybean products as cancer preventive agents
5. A novel methionine-rich protein from soybean cotyledon: Cloning and characterization of cDNA (accession no. AF005030)
6. A soybean cDNA encoding a chromatin-binding peptide inhibits mitosis of mammalian cells
7. The cancer-chromatin connection
8. Arg-Gly-Asp. A versatile cell recognition signal
9. Fibronectin and integrins in invasion and metastasis
10. Rehnoids and the control of adhesion
11. Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
12. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division
13. High dietary retinoic acid inhibits tumor promotion and malignant conversion in a two-stage skin carcinogenesis protocol using 7,12-dimethylbenz[a]anthracene as the initiator and mezerein as the tumor promoter in female SENCAR mice
14. Cancer prevention by protease inhibitors
15. Combining evolutionary information and neural networks to predict protein secondary structure
16. The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1
17. Heterochromatin protein Hp1Hsβ (p25β) and its colocalization with centromeres in mitosis
18. Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster
19. Histone acetylation in chromatin structure and transcription
20. Histone acetylation and transcriptional regulatory mechanisms
21. Sodium butyrate inhibits histone deacetylation in cultured cells
22. The retinoblastoma protein and cell cycle control
23. Retinoblastoma protein recruits histone deacetylase to repress transcription
24. Retinoblastoma protein represses transcription by recruiting a histone deacetylase
25. Rb interacts with histone deacetylase to repress transcription
26. E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
27. 12S have a homologous activation domain regulated by Rb and CBP