Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway

Translational Research

Volumn 161, Issue 2, 2013, Pages 89-98

  Li, Yanmei ^a   Wang, Shaogui ^a   Wang, Ying ^a   Zhou, Chun ^a   Chen, Guangxing ^b   Shen, Weixing ^c   Li, Cuixian ^a   Lin, Wei ^a   Lin, Sisi ^a   Huang, Heqing ^a   Liu, Peiqing ^a   Shen, Xiaoyan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

ART; artesunate; c Jun N terminal kinase; CIA; collagen induced arthritis; ERK; extracellular signal regulated kinase; fibroblast like synoviocyte; FLS; JNK; Lef; leflunomide; MAPK; metalloproteinase; mitogen activated protein kinase; MMP; NF B; nuclear factor kappa B; RA; rheumatoid arthritis; SDS PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; TNF ; tumor necrosis factor alpha

Indexed keywords

ARTESUNATE; GELATINASE A; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE DESTRUCTION; CANCER ADJUVANT THERAPY; CARTILAGE DEGENERATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; EDEMA; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT DURATION;

EID: 84872389385     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2012.06.001     Document Type: Article

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