Solid Phase Synthesis of Mitochondrial Triphenylphosphonium-Vitamin E Metabolite Using a Lysine Linker for Reversal of Oxidative Stress

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Mossalam, Mohanad ^a   Soto, Jamie ^b   Lim, Carol S ^a   Abel, E Dale ^b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5,7,8 TETRAMETHYL 2 (2' CARBOXYETHYL) 6 HYDROXYCHROMAN; [4 [[1 AMINO 6 [3 (HYDROXYL 2,5,7,8 TETRAMETHYLCHROMAN 2 YL)PROPANAMIDO] 1 OXOHEXAN 2 YL]AMINO] 4 OXOBUTYL]TRIPHENYLPHOSPHONIUM; ALPHA TOCOPHEROL DERIVATIVE; LYSINE; PHOSPHONIUM DERIVATIVE; TOCOPHEROL; TRIPHENYLPHOSPHONIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG STRUCTURE; DRUG TARGETING; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; SOLID PHASE SYNTHESIS;

ANIMALS; CATTLE; CHROMANS; LYSINE; MASS SPECTROMETRY; MICE; MITOCHONDRIA; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; PROPIONATES; REACTIVE OXYGEN SPECIES; SOLID-PHASE SYNTHESIS TECHNIQUES; VITAMIN E;

BOVINAE; MUS;

EID: 84872359347     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053272     Document Type: Article

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