β-Lactam therapeutic drug monitoring in the critically ill: Optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia

International Journal of Antimicrobial Agents

Volumn 41, Issue 2, 2013, Pages 162-166

  Hayashi, Yoshiro ^a,b,c   Lipman, Jeffrey ^b,c   Udy, Andrew A ^b,c   Ng, Mandy ^b,c   McWhinney, Brett ^d   Ungerer, Jacobus ^d   Lust, Karin ^b   Roberts, Jason A ^b,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d Pathology Queensland   (Australia)

Author keywords

Lactams; Intensive care; Pharmacokinetics; Therapeutic drug monitoring

Indexed keywords

ALBUMIN; BETA LACTAM ANTIBIOTIC; CREATININE; ERTAPENEM; FLUCLOXACILLIN; MEROPENEM; UREA;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIUM CULTURE; BRAIN EMBOLISM; BRAIN INFECTION; BRAIN VENTRICULITIS; CASE REPORT; CONSCIOUSNESS DISORDER; CRITICALLY ILL PATIENT; DETERIORATION; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EXPOSURE; DRUG MEGADOSE; DRUG MONITORING; DRUG PENETRATION; ESOPHAGUS RESECTION; FEMALE; FEVER; GLASGOW COMA SCALE; HIP PAIN; HUMAN; HYPERVOLEMIA; HYPOALBUMINEMIA; KIDNEY DISEASE; LETHARGY; MALAISE; MALE; MASTOIDITIS; MEDIASTINITIS; MINIMUM INHIBITORY CONCENTRATION; PLEOCYTOSIS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RIGOR; STAPHYLOCOCCUS INFECTION; UREA BLOOD LEVEL; UREMIA; VOMITING;

ADULT; AGED; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BETA-LACTAMS; CRITICAL ILLNESS; DRUG MONITORING; FEMALE; HUMANS; HYPOALBUMINEMIA; INTENSIVE CARE; KIDNEY; MALE;

EID: 84872339888     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.10.002     Document Type: Article

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