Evaluation of dopamine D2/D3 and serotonin 5-HT 2A receptor occupancy for a novel antipsychotic, lurasidone, in conscious common marmosets using small-animal positron emission tomography

Psychopharmacology

Volumn 225, Issue 2, 2013, Pages 329-339

  Nakazawa, Shunsuke ^a,b   Yokoyama, Chihiro ^a   Nishimura, Naohiro ^b   Horisawa, Tomoko ^b   Kawasaki, Akihiro ^a   Mizuma, Hiroshi ^a   Doi, Hisashi ^a   Onoe, Hirotaka ^a  

^a RIKEN   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Antipsychotic drug (APD); Dopamine D2 D3 receptor; Lurasidone; Nonhuman primate; Olanzapine; Positron emission tomography (PET); Serotonin 5 HT2A receptor

Indexed keywords

CARBON VOLINANSERIN C 11; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; LURASIDONE; OLANZAPINE; RACLOPRIDE C 11; RADIOPHARMACEUTICAL AGENT; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CALLITHRIX; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; IN VIVO STUDY; MALE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RECEPTOR OCCUPANCY;

ANIMALS; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CALLITHRIX; CORPUS STRIATUM; ISOINDOLES; MALE; POSITRON-EMISSION TOMOGRAPHY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; THIAZOLES;

EID: 84872331092     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2815-9     Document Type: Article

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