Serotonin 5-HT2 receptors in schizophrenic patients studied by positron emission tomography

Life Sciences

Volumn 66, Issue 25, 2000, Pages 2455-2464

  Okubo, Yoshiro ^a,b   Suhara, Tetsuya ^b   Suzuki, Kazutoshi ^b   Kobayashi, Kaoru ^b   Inoue, Osamu ^b   Terasaki, Omi ^a   Someya, Yasuhiro ^a,b   Sassa, Takeshi ^a,b   Sudo, Yasuhiko ^b   Matsushima, Eisuke ^a   Iyo, Masaomi ^b   Tateno, Yukio ^b   Toru, Michio ^a,b  

^a Div C   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

5 HT2 receptors; 11C N methylspiperone; Positron emission tomography; Prefrontal cortex; Schizophrenia

Indexed keywords

3 METHYLSPIPERONE C 11; BROMPERIDOL; CHLORPROMAZINE; DOPAMINE 1 RECEPTOR; EMONAPRIDE; HALOPERIDOL; NEUROLEPTIC AGENT; SEROTONIN 2 RECEPTOR; SULPIRIDE; 3 METHYLSPIPERONE; 3-N-METHYLSPIPERONE; CARBON; DIAGNOSTIC AGENT; DRUG DERIVATIVE; SEROTONIN RECEPTOR; SPIPERONE;

ADULT; ARTICLE; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; RECEPTOR BINDING; SCHIZOPHRENIA; COMPUTER ASSISTED EMISSION TOMOGRAPHY; METABOLISM;

ADULT; CARBON ISOTOPES; CEREBRAL CORTEX; HUMANS; RECEPTORS, SEROTONIN; SCHIZOPHRENIA; SPIPERONE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0034640058     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)80005-3     Document Type: Article

References (49)

1. Breier A. Schiozophr. Res. 14:1995;187-202.
2. Ohuoha D.C., Hyde T.M., Kleinman J.E. Psychopharmacology. 112:1993;S5-S15.
3. Nyberg S., Farde L., Eriksson L., Halldin C., Eriksson B. Psychopharmacology. 110:1993;265-272.
4. Farde L., Nyberg S., Oxenstierna G., Nakashima Y., Halldin C., Ericsson B. J. Clin. Psychopharm. 15:1995;S19-S23.
5. Meltzer H.Y. J. Clin. Psychopharm. 15:1995;S2-S3.
6. Nordström A.L., Farde L., Nyberg S., Karlsson P., Halldin C., Sedvall G. Am. J. Psychiat. 152:1995;1444-1449.
7. Busatto G.F., Kerwin R.W. J. Psychopharmacolgy. 11:1997;3-12.
8. Kapur S., Remington G. Am. J. Psychiat. 153:1996;466-475.
9. Bennett J.J., Enna S.J., Bylund D.B., Gillin J.C., Wyatt R.J., Snyder S.H. Arch. Gen. Psychiat. 36:1979;927-934.
10. Mita T., Hanada S., Nishino N., Kuno T., Nakai H., Yamadori T., Mizoi Y., Tanaka C. Biol. Psychiat. 21:1986;1407-1414.
11. Arora R.C., Meltzer H.Y. J. Neural Transm. Gen. 85:1991;19-29.
12. Laruelle M., Abi D.A., Casanova M.F., Toti R., Weinberger D.R., Kleinman J.E. Arch. Gen. Psychiat. 50:1993;810-818.
13. Burnet P.W., Eastwood S.L., Harrison P.J. Neuropsychopharmacol. 15:1996;442-455.
14. Dean B., Hayes W. Schizophr. Res. 21:1996;133-139.
15. Frost J.J., Smith A.C., Kuhar M.J., Dannals R.F., Wagner H.J. Life Sci. 40:1987;987-995.
16. Crouzel C., Guillaume M., Barre L., Lemaire C., Pike V.W. Int. J. Radiat. Applications & Instrumentation Part B, Nuclear Medicine & Biology. 19:1992;857-870.
17. Meltzer C.C., Smith G., Dekosky S.T., Pollock B.G., Mathis C.A., Moore R.Y., Kupfer D.J., Reynolds C.R. Neuropsychopharmacol. 18:1998;407-430.
18. Trichard C., Paillere M.M., Attar L.D., Blin J., Feline A., Martinot J.L. Schizophr. Res. 31:1998;13-17.
19. Lewis R., Kapur S., Jones C., Dasilvs J., Brown G.M., Wilson A.A., Houle S., Zipursky R.B. Am. J. Psychiat. 156:1999;72-78.
20. Okubo Y., Suhara T., Suzuki K., Kobayashi K., Inoue O., Terasaki O., Someya Y., Sassa T., Sudo Y., Matsushima E., Iyo M., Tateno Y., Toru M. Nature. 385:1997;634-636.
21. Okubo Y., Suhara T., Sudo Y., Toru M. Mol. Psychiatr. 2:1997;291-294.
22. Lyon R.A., Titeler M., Frost J.J., Whitehouse P.J., Wong D.F., Wagner H.J., Dannals R.F., Links J.M., Kuhar M.J. J. Neurosci. 6:1986;2941-2949.
23. Hall H., Wedel I., Halldin C., Kopp J., Farde L. J. Neurochem. 55:1990;2048-2057.
24. Martres M.P., Bouthenet M.L., Sales N., Sokoloff P., Schwartz J.C. Science. 228:1985;752-755.
25. Hall H., Farde L., Sedvall G. J. Neural Transm. 73:1988;7-21.
26. Lidow M.S., Goldman R.P., Rankic P., Innis R.B. Proc. Natl. Acad.Sci. USA. 86:1989;6412-6416.
27. Wong D.F., Wagner H.J., Dannals R.F., Links J.M., Frost J.J., Ravert H.T., Wilson A.A., Rosenbaum A.E., Gjedde A., Douglas K.H. Science. 226:1984;1393-1396.
28. Yonezawa Y., Iyo M., Itoh T., Fukuda H., Yamasaki T., Inoue O., Suhara T., Shinotoh H., Nishio M., Tohgi H., Tateno Y. Jap. J. Nucl. Med. 28:1991;63-69.
29. Nyberg S., Farde L., Halldin C. Neuropsychopharmacol. 16:1997;1-7.
30. Andree B., Nyberg S., Ito H., Ginovart N., Brunner F., Jaquet F., Halldin C., Farde L. J. Clin. Psychopharm. 18:1998;317-323.
31. Ito H., Nyberg S., Halldin C., Lundkvist C., Farden L. J. Nucl. Med. 39:1998;208-214.
32. Leysen J.E., Gommeren W. Drug Develop. Res. 8:1986;119-131.
33. Asahina M., Shinotoh H., Hirayama K., Suhara T., Shishido F., Inoue O., Tateno Y. Acta Neurol. Scand. 91:1995;437-443.
34. Schotte A., Maloteaux J.M., Laduron P.M. Brain Res. 276:1983;231-235.
35. Pazos A., Probst A., Palacios J.M. Neuroscience. 21:1987;123-139.
36. Suhara T., Fukuda H., Inoue O., Itoh T., Suzuki K., Yamasaki T., Tateno Y. Psychopharmacology. 103:1991;41-45.
37. Mintun M., Raichile M., Kilbourn M., Wooten G., Welch M. Ann. Neurol. 15:1984;217-227.
38. Wang G.J., Volkow N.D., Logan J., Fowler J.S., Schlyer D., Macgregor R.R., Hitzemann R.J., Gur R.C., Wolf A.P. Life Sci. 56:1995;53.
39. Gurevich E.V., Joyce J.N. Biol. Psychiat. 42:1997;529-545.
40. Whitaker P.M., Crow T.J., Ferrier I.N. Arch. Gen. Psychiat. 38:1981;278-280.
41. Lee T., Tang S.W. Psychiat. Res. 12:1984;277-285.
42. Wilmot C.A., Szczepanik A.M. Brain Res. 487:1989;288-298.
43. O'dell S.J., La H.G., Widmark C.B., Shapiro R.M., Potkin S.G., Marshall J.F. Synapse. 6:1990;146-153.
44. Kuoppamaki M., Palvimaki E.P., Hietala J., Syvalahti E. Neuropsychopharmacol. 13:1995;139-150.
45. Burnet P.W., Chen C.P., McGowan S., Franklin M., Harrison P.J. Neuroscience. 73:1996;531-540.
46. Andree T.H., Mikuni M., Tong C.Y., Koenig J.I., Meltzer H.Y. J. Neurochem. 46:1986;191-197.
47. Mikuni M., Meltzer H.Y. Life Sci. 34:1984;87-92.
48. Kapur S. Mol. Psychiatr. 3:1998;135-140.
49. Meltzer H.Y., Matsubara S., Lee J.C. J. Pharmacol. Exp. Ther. 251:1989;238-246.