-
1
-
-
50149083752
-
Mammalian Rho GTPases. New insights into their functions from in vivo studies
-
Heasman, S. J., and Ridley, A. J. (2008) Mammalian Rho GTPases. New insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol. 9, 690-701
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
2
-
-
27944479854
-
Rho GTPases. Biochemistry and biology
-
Jaffe, A. B., and Hall, A. (2005) Rho GTPases. Biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21, 247-269
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
3
-
-
1642393863
-
Molecular basis for Rho GTPase signaling specificity
-
DOI 10.1023/B:BREA.0000018427.84929.5c
-
Karnoub, A. E., Symons, M., Campbell, S. L., and Der, C. J. (2004) Molecular basis for Rho GTPase signaling specificity. Breast Cancer Res. Treat. 84, 61-71 (Pubitemid 38388861)
-
(2004)
Breast Cancer Research and Treatment
, vol.84
, Issue.1
, pp. 61-71
-
-
Karnoub, A.E.1
Symons, M.2
Campbell, S.L.3
Der, C.J.4
-
4
-
-
13444252631
-
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
-
DOI 10.1038/nrm1587
-
Rossman, K. L., Der, C. J., and Sondek, J. (2005) GEF means go. Turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (Pubitemid 40215811)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.2
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
5
-
-
34548472221
-
GEF what? Dock180 and related proteins help Rac to polarize cells in new ways
-
Côté, J. F., and Vuori, K. (2007) GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. Trends Cell Biol. 17, 383-393
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 383-393
-
-
Côté, J.F.1
Vuori, K.2
-
6
-
-
70249105718
-
Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor
-
Yang, J., Zhang, Z., Roe, S. M., Marshall, C. J., and Barford, D. (2009) Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science 325, 1398-1402
-
(2009)
Science
, vol.325
, pp. 1398-1402
-
-
Yang, J.1
Zhang, Z.2
Roe, S.M.3
Marshall, C.J.4
Barford, D.5
-
7
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera, E., Haney, L., Grimsley, C., Lu, M., Walk, S. F., Tosello-Trampont, A. C., Macara, I. G., Madhani, H., Fink, G. R., and Ravichandran, K. S. (2002) Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat. Cell Biol. 4, 574-582
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
Macara, I.G.7
Madhani, H.8
Fink, G.R.9
Ravichandran, K.S.10
-
8
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Côté, J. F., and Vuori, K. (2002) Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115, 4901-4913
-
(2002)
J. Cell Sci.
, vol.115
, pp. 4901-4913
-
-
Côté, J.F.1
Vuori, K.2
-
9
-
-
38349143073
-
Drosophila ELMO/CED-12 interacts with myoblast city to direct myoblast fusion and ommatidial organization
-
Geisbrecht, E. R., Haralalka, S., Swanson, S. K., Florens, L., Washburn, M. P., and Abmayr, S. M. (2008) Drosophila ELMO/CED-12 interacts with myoblast city to direct myoblast fusion and ommatidial organization. Dev. Biol. 314, 137-149
-
(2008)
Dev. Biol.
, vol.314
, pp. 137-149
-
-
Geisbrecht, E.R.1
Haralalka, S.2
Swanson, S.K.3
Florens, L.4
Washburn, M.P.5
Abmayr, S.M.6
-
10
-
-
0035812719
-
Guidance of cell migration by the Drosophila PDGF/VEGF receptor
-
DOI 10.1016/S0092-8674(01)00502-5
-
Duchek, P., Somogyi, K., Jékely, G., Beccari, S., and Rørth, P. (2001) Guidance of cell migration by the Drosophila PDGF/VEGF receptor. Cell 107, 17-26 (Pubitemid 32972034)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 17-26
-
-
Duchek, P.1
Somogyi, K.2
Jekely, G.3
Beccari, S.4
Rorth, P.5
-
11
-
-
0030816709
-
Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization
-
DOI 10.1083/jcb.138.3.589
-
Erickson, M. R., Galletta, B. J., and Abmayr, S. M. (1997) Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization. J. Cell Biol. 138, 589-603 (Pubitemid 27349840)
-
(1997)
Journal of Cell Biology
, vol.138
, Issue.3
, pp. 589-603
-
-
Erickson, M.R.S.1
Galletta, B.J.2
Abmayr, S.M.3
-
12
-
-
0028980059
-
Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development
-
Rushton, E., Drysdale, R., Abmayr, S. M., Michelson, A. M., and Bate, M. (1995) Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development. Development 121, 1979-1988
-
(1995)
Development
, vol.121
, pp. 1979-1988
-
-
Rushton, E.1
Drysdale, R.2
Abmayr, S.M.3
Michelson, A.M.4
Bate, M.5
-
13
-
-
0032473981
-
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
-
Wu, Y. C., and Horvitz, H. R. (1998) C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392, 501-504
-
(1998)
Nature
, vol.392
, pp. 501-504
-
-
Wu, Y.C.1
Horvitz, H.R.2
-
14
-
-
0033771902
-
CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
-
Reddien, P. W., and Horvitz, H. R. (2000) CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nat. Cell Biol. 2, 131-136
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 131-136
-
-
Reddien, P.W.1
Horvitz, H.R.2
-
15
-
-
50249145697
-
UPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180
-
Smith, H. W., Marra, P., and Marshall, C. J. (2008) uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180. J. Cell Biol. 182, 777-790
-
(2008)
J. Cell Biol.
, vol.182
, pp. 777-790
-
-
Smith, H.W.1
Marra, P.2
Marshall, C.J.3
-
16
-
-
0032825266
-
Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
-
DOI 10.1083/jcb.146.5.1107
-
Cheresh, D. A., Leng, J., and Klemke, R. L. (1999) Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. J. Cell Biol. 146, 1107-1116 (Pubitemid 29430451)
-
(1999)
Journal of Cell Biology
, vol.146
, Issue.5
, pp. 1107-1116
-
-
Cheresh, D.A.1
Leng, J.2
Klemke, R.L.3
-
17
-
-
0032544426
-
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex
-
DOI 10.1074/jbc.273.38.24479
-
Kiyokawa, E., Hashimoto, Y., Kurata, T., Sugimura, H., and Matsuda, M. (1998) Evidence that DOCK180 up-regulates signals from the CrkIIp130(Cas) complex. J. Biol. Chem. 273, 24479-24484 (Pubitemid 28454941)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.38
, pp. 24479-24484
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kurata, T.3
Sugimura, H.4
Matsuda, M.5
-
18
-
-
55749114582
-
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo
-
Laurin, M., Fradet, N., Blangy, A., Hall, A., Vuori, K., and Côté, J. F. (2008) The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc. Natl. Acad. Sci. U.S.A. 105, 15446-15451
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15446-15451
-
-
Laurin, M.1
Fradet, N.2
Blangy, A.3
Hall, A.4
Vuori, K.5
Côté, J.F.6
-
19
-
-
36248987290
-
BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
-
DOI 10.1038/nature06329, PII NATURE06329
-
Park, D., Tosello-Trampont, A. C., Elliott, M. R., Lu, M., Haney, L. B., Ma, Z., Klibanov, A. L., Mandell, J. W., and Ravichandran, K. S. (2007) BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature 450, 430-434 (Pubitemid 350126756)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 430-434
-
-
Park, D.1
Tosello-Trampont, A.-C.2
Elliott, M.R.3
Lu, M.4
Haney, L.B.5
Ma, Z.6
Klibanov, A.L.7
Mandell, J.W.8
Ravichandran, K.S.9
-
20
-
-
40849119785
-
Myoblasts and macrophages share molecular components that contribute to cell-cell fusion
-
DOI 10.1083/jcb.200707191
-
Pajcini, K. V., Pomerantz, J. H., Alkan, O., Doyonnas, R., and Blau, H. M. (2008) Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. J. Cell Biol. 180, 1005-1019 (Pubitemid 351398425)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.5
, pp. 1005-1019
-
-
Pajcini, K.V.1
Pomerantz, J.H.2
Alkan, O.3
Doyonnas, R.4
Blau, H.M.5
-
21
-
-
78349310110
-
DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4
-
Sanematsu, F., Hirashima, M., Laurin, M., Takii, R., Nishikimi, A., Kitajima, K., Ding, G., Noda, M., Murata, Y., Tanaka, Y., Masuko, S., Suda, T., Meno, C., Côté, J. F., Nagasawa, T., and Fukui, Y. (2010) DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. Circ. Res. 107, 1102-1105
-
(2010)
Circ. Res.
, vol.107
, pp. 1102-1105
-
-
Sanematsu, F.1
Hirashima, M.2
Laurin, M.3
Takii, R.4
Nishikimi, A.5
Kitajima, K.6
Ding, G.7
Noda, M.8
Murata, Y.9
Tanaka, Y.10
Masuko, S.11
Suda, T.12
Meno, C.13
Côté, J.F.14
Nagasawa, T.15
Fukui, Y.16
-
22
-
-
17944375813
-
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
-
DOI 10.1038/35090591
-
Fukui, Y., Hashimoto, O., Sanui, T., Oono, T., Koga, H., Abe, M., Inayoshi, A., Noda, M., Oike, M., Shirai, T., and Sasazuki, T. (2001) Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature 412, 826-831 (Pubitemid 32801465)
-
(2001)
Nature
, vol.412
, Issue.6849
, pp. 826-831
-
-
Fukui, Y.1
Hashimoto, O.2
Sanui, T.3
Oono, T.4
Koga, H.5
Abe, M.6
Inayoshi, A.7
Noda, M.8
Oike, M.9
Shirai, T.10
Sasazuki, T.11
-
23
-
-
79955638351
-
The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts
-
Vives, V., Laurin, M., Cres, G., Larrousse, P., Morichaud, Z., Noel, D., Côté, J. F., and Blangy, A. (2011) The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts. J. Bone Miner. Res. 26, 1099-1110
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 1099-1110
-
-
Vives, V.1
Laurin, M.2
Cres, G.3
Larrousse, P.4
Morichaud, Z.5
Noel, D.6
Côté, J.F.7
Blangy, A.8
-
24
-
-
17944376439
-
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
-
DOI 10.1016/S0092-8674(01)00520-7
-
Gumienny, T. L., Brugnera, E., Tosello-Trampont, A. C., Kinchen, J. M., Haney, L. B., Nishiwaki, K., Walk, S. F., Nemergut, M. E., Macara, I. G., Francis, R., Schedl, T., Qin, Y., Van Aelst, L., Hengartner, M. O., and Ravichandran, K. S. (2001) CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 107, 27-41 (Pubitemid 32972035)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 27-41
-
-
Gumienny, T.L.1
Brugnera, E.2
Tosello-Trampont, A.-C.3
Kinchen, J.M.4
Haney, L.B.5
Nishiwaki, K.6
Walk, S.F.7
Nemergut, M.E.8
Macara, I.G.9
Francis, R.10
Schedl, T.11
Qin, Y.12
Van Aelst, L.13
Hengartner, M.O.14
Ravichandran, K.S.15
-
25
-
-
0035487807
-
C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment
-
Wu, Y. C., Tsai, M. C., Cheng, L. C., Chou, C. J., and Weng, N. Y. (2001) C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment. Dev. Cell 1, 491-502
-
(2001)
Dev. Cell
, vol.1
, pp. 491-502
-
-
Wu, Y.C.1
Tsai, M.C.2
Cheng, L.C.3
Chou, C.J.4
Weng, N.Y.5
-
26
-
-
0035487646
-
The C. elegans PH Domain Protein CED-12 Regulates Cytoskeletal Reorganization via a Rho/Rac GTPase Signaling Pathway
-
DOI 10.1016/S1534-5807(01)00058-2, PII S1534580701000582
-
Zhou, Z., Caron, E., Hartwieg, E., Hall, A., and Horvitz, H. R. (2001) The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev. Cell 1, 477-489 (Pubitemid 33586100)
-
(2001)
Developmental Cell
, vol.1
, Issue.4
, pp. 477-489
-
-
Zhou, Z.1
Caron, E.2
Hartwieg, E.3
Hall, A.4
Horvitz, H.R.5
-
27
-
-
78649329795
-
An evolutionarily conserved autoinhibitory molecular switch inELMOproteins regulates Rac signaling
-
Patel, M., Margaron, Y., Fradet, N., Yang, Q., Wilkes, B., Bouvier, M., Hofmann, K., and Côté, J. F. (2010) An evolutionarily conserved autoinhibitory molecular switch inELMOproteins regulates Rac signaling. Curr. Biol. 20, 2021-2027
-
(2010)
Curr. Biol.
, vol.20
, pp. 2021-2027
-
-
Patel, M.1
Margaron, Y.2
Fradet, N.3
Yang, Q.4
Wilkes, B.5
Bouvier, M.6
Hofmann, K.7
Côté, J.F.8
-
28
-
-
80655125028
-
The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family
-
Patel, M., Chiang, T. C., Tran, V., Lee, F. J., and Côté, J. F. (2011) The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family. J. Biol. Chem. 286, 38969-38979
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 38969-38979
-
-
Patel, M.1
Chiang, T.C.2
Tran, V.3
Lee, F.J.4
Côté, J.F.5
-
29
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
DOI 10.1038/nature01817
-
Katoh, H., and Negishi, M. (2003) RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424, 461-464 (Pubitemid 36917498)
-
(2003)
Nature
, vol.424
, Issue.6947
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
-
30
-
-
84857751765
-
Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms
-
Hanawa-Suetsugu, K., Kukimoto-Niino, M., Mishima-Tsumagari, C., Akasaka, R., Ohsawa, N., Sekine, S., Ito, T., Tochio, N., Koshiba, S., Kigawa, T., Terada, T., Shirouzu, M., Nishikimi, A., Uruno, T., Katakai, T., Kinashi, T., Kohda, D., Fukui, Y., and Yokoyama, S. (2012) Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc. Natl. Acad. Sci. U.S.A. 109, 3305-3310
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 3305-3310
-
-
Hanawa-Suetsugu, K.1
Kukimoto-Niino, M.2
Mishima-Tsumagari, C.3
Akasaka, R.4
Ohsawa, N.5
Sekine, S.6
Ito, T.7
Tochio, N.8
Koshiba, S.9
Kigawa, T.10
Terada, T.11
Shirouzu, M.12
Nishikimi, A.13
Uruno, T.14
Katakai, T.15
Kinashi, T.16
Kohda, D.17
Fukui, Y.18
Yokoyama, S.19
-
31
-
-
34447517405
-
Two distinct modes of guidance signalling during collective migration of border cells
-
DOI 10.1038/nature05965, PII NATURE05965
-
Bianco, A., Poukkula, M., Cliffe, A., Mathieu, J., Luque, C. M., Fulga, T. A., and Rørth, P. (2007) Two distinct modes of guidance signalling during collective migration of border cells. Nature 448, 362-365 (Pubitemid 47080343)
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 362-365
-
-
Bianco, A.1
Poukkula, M.2
Cliffe, A.3
Mathieu, J.4
Luque, C.M.5
Fulga, T.A.6
Rorth, P.7
-
32
-
-
0032213953
-
Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes
-
Nolan, K. M., Barrett, K., Lu, Y., Hu, K. Q., Vincent, S., and Settleman, J. (1998) Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev. 12, 3337-3342 (Pubitemid 28520982)
-
(1998)
Genes and Development
, vol.12
, Issue.21
, pp. 3337-3342
-
-
Nolan, K.M.1
Barrett, K.2
Lu, Y.3
Hu, K.-Q.4
Vincent, S.5
Settleman, J.6
-
33
-
-
33748457564
-
DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis
-
Kunisaki, Y., Nishikimi, A., Tanaka, Y., Takii, R., Noda, M., Inayoshi, A., Watanabe, K., Sanematsu, F., Sasazuki, T., Sasaki, T., and Fukui, Y. (2006) DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. J. Cell Biol. 174, 647-652
-
(2006)
J. Cell Biol.
, vol.174
, pp. 647-652
-
-
Kunisaki, Y.1
Nishikimi, A.2
Tanaka, Y.3
Takii, R.4
Noda, M.5
Inayoshi, A.6
Watanabe, K.7
Sanematsu, F.8
Sasazuki, T.9
Sasaki, T.10
Fukui, Y.11
-
34
-
-
23144450821
-
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
-
Côté, J. F., Motoyama, A. B., Bush, J. A., and Vuori, K. (2005) A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling. Nat. Cell Biol. 7, 797-807
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 797-807
-
-
Côté, J.F.1
Motoyama, A.B.2
Bush, J.A.3
Vuori, K.4
-
35
-
-
58149292257
-
An α-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling
-
Komander, D., Patel, M., Laurin, M., Fradet, N., Pelletier, A., Barford, D., and Côté, J. F. (2008) An α-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling. Mol. Biol. Cell 19, 4837-4851
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4837-4851
-
-
Komander, D.1
Patel, M.2
Laurin, M.3
Fradet, N.4
Pelletier, A.5
Barford, D.6
Côté, J.F.7
-
36
-
-
10744223552
-
Dock180 and ELMO1 Proteins Cooperate to Promote Evolutionarily Conserved Rac-dependent Cell Migration
-
DOI 10.1074/jbc.M307087200
-
Grimsley, C. M., Kinchen, J. M., Tosello-Trampont, A. C., Brugnera, E., Haney, L. B., Lu, M., Chen, Q., Klingele, D., Hengartner, M. O., and Ravichandran, K. S. (2004) Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration. J. Biol. Chem. 279, 6087-6097 (Pubitemid 38220641)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.7
, pp. 6087-6097
-
-
Grimsley, C.M.1
Kinchen, J.M.2
Tosello-Trampont, A.-C.3
Brugnera, E.4
Haney, L.B.5
Lu, M.6
Chen, Q.7
Klingele, D.8
Hengartner, M.O.9
Ravichandran, K.S.10
-
37
-
-
65249117435
-
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis
-
Nishikimi, A., Fukuhara, H., Su, W., Hongu, T., Takasuga, S., Mihara, H., Cao, Q., Sanematsu, F., Kanai, M., Hasegawa, H., Tanaka, Y., Shibasaki, M., Kanaho, Y., Sasaki, T., Frohman, M. A., and Fukui, Y. (2009) Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science 324, 384-387
-
(2009)
Science
, vol.324
, pp. 384-387
-
-
Nishikimi, A.1
Fukuhara, H.2
Su, W.3
Hongu, T.4
Takasuga, S.5
Mihara, H.6
Cao, Q.7
Sanematsu, F.8
Kanai, M.9
Hasegawa, H.10
Tanaka, Y.11
Shibasaki, M.12
Kanaho, Y.13
Sasaki, T.14
Frohman, M.A.15
Fukui, Y.16
-
38
-
-
65249151857
-
Cell biology. Two lipids that give direction
-
Côté, J. F., and Vuori, K. (2009) Cell biology. Two lipids that give direction. Science 324, 346-347
-
(2009)
Science
, vol.324
, pp. 346-347
-
-
Côté, J.F.1
Vuori, K.2
-
39
-
-
67650462263
-
Integrin-linked kinase interactions with ELMO2 modulate cell polarity
-
Ho, E., Irvine, T., Vilk, G. J., Lajoie, G., Ravichandran, K. S., D'Souza, S. J., and Dagnino, L. (2009) Integrin-linked kinase interactions with ELMO2 modulate cell polarity. Mol. Biol. Cell 20, 3033-3043
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 3033-3043
-
-
Ho, E.1
Irvine, T.2
Vilk, G.J.3
Lajoie, G.4
Ravichandran, K.S.5
D'Souza, S.J.6
Dagnino, L.7
-
41
-
-
0034599768
-
An epidermal plakin that integrates actin and microtubule networks at cellular junctions
-
DOI 10.1083/jcb.149.1.195
-
Karakesisoglou, I., Yang, Y., and Fuchs, E. (2000) An epidermal plakin that integrates actin and microtubule networks at cellular junctions. J. Cell Biol. 149, 195-208 (Pubitemid 30196709)
-
(2000)
Journal of Cell Biology
, vol.149
, Issue.1
, pp. 195-208
-
-
Karakesisoglou, I.1
Yang, Y.2
Fuchs, E.3
-
42
-
-
0344845405
-
ACF7: An essential integrator of microtubule dynamics
-
DOI 10.1016/S0092-8674(03)00813-4
-
Kodama, A., Karakesisoglou, I., Wong, E., Vaezi, A., and Fuchs, E. (2003) ACF7. An essential integrator of microtubule dynamics. Cell 115, 343-354 (Pubitemid 37487707)
-
(2003)
Cell
, vol.115
, Issue.3
, pp. 343-354
-
-
Kodama, A.1
Karakesisoglou, I.2
Wong, E.3
Vaezi, A.4
Fuchs, E.5
-
43
-
-
52949098421
-
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity
-
Wu, X., Kodama, A., and Fuchs, E. (2008) ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell 135, 137-148
-
(2008)
Cell
, vol.135
, pp. 137-148
-
-
Wu, X.1
Kodama, A.2
Fuchs, E.3
-
44
-
-
79551675515
-
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β
-
Wu, X., Shen, Q. T., Oristian, D. S., Lu, C. P., Zheng, Q., Wang, H. W., and Fuchs, E. (2011) Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell 144, 341-352
-
(2011)
Cell
, vol.144
, pp. 341-352
-
-
Wu, X.1
Shen, Q.T.2
Oristian, D.S.3
Lu, C.P.4
Zheng, Q.5
Wang, H.W.6
Fuchs, E.7
-
45
-
-
0033552634
-
Microtubule actin cross-linking factor (MACF). A hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons
-
Leung, C. L., Sun, D., Zheng, M., Knowles, D. R., and Liem, R. K. (1999) Microtubule actin cross-linking factor (MACF). A hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons. J. Cell Biol. 147, 1275-1286
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1275-1286
-
-
Leung, C.L.1
Sun, D.2
Zheng, M.3
Knowles, D.R.4
Liem, R.K.5
-
46
-
-
0033585009
-
Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins
-
Sun, Y., Zhang, J., Kraeft, S. K., Auclair, D., Chang, M. S., Liu, Y., Sutherland, R., Salgia, R., Griffin, J. D., Ferland, L. H., and Chen, L. B. (1999) Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins. J. Biol. Chem. 274, 33522-33530 (Pubitemid 129511661)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.47
, pp. 33522-33530
-
-
Sun, Y.1
Zhang, J.2
Kraeft, S.-K.3
Auclair, D.4
Chang, M.-S.5
Liu, Y.6
Sutherland, R.7
Salgia, R.8
Griffin, J.D.9
Ferland, L.H.10
Chen, L.B.11
-
47
-
-
69649101282
-
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth
-
Sanchez-Soriano, N., Travis, M., Dajas-Bailador, F., Gonçalves- Pimentel, C., Whitmarsh, A. J., and Prokop, A. (2009) Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth. J. Cell Sci. 122, 2534-2542
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2534-2542
-
-
Sanchez-Soriano, N.1
Travis, M.2
Dajas-Bailador, F.3
Gonçalves-Pimentel, C.4
Whitmarsh, A.J.5
Prokop, A.6
-
48
-
-
78649863822
-
ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells
-
Zaoui, K., Benseddik, K., Daou, P., Salaün, D., and Badache, A. (2010) ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells. Proc. Natl. Acad. Sci. U.S.A. 107, 18517-18522
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 18517-18522
-
-
Zaoui, K.1
Benseddik, K.2
Daou, P.3
Salaün, D.4
Badache, A.5
-
49
-
-
56649084971
-
Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading
-
Dubin-Thaler, B. J., Hofman, J. M., Cai, Y., Xenias, H., Spielman, I., Shneidman, A. V., David, L. A., Döbereiner, H. G., Wiggins, C. H., and Sheetz, M. P. (2008) Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading. PLoS One 3, e3735
-
(2008)
PLoS One
, vol.3
-
-
Dubin-Thaler, B.J.1
Hofman, J.M.2
Cai, Y.3
Xenias, H.4
Spielman, I.5
Shneidman, A.V.6
David, L.A.7
Döbereiner, H.G.8
Wiggins, C.H.9
Sheetz, M.P.10
-
50
-
-
79958064117
-
SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility
-
Parrini, M. C., Sadou-Dubourgnoux, A., Aoki, K., Kunida, K., Biondini, M., Hatzoglou, A., Poullet, P., Formstecher, E., Yeaman, C., Matsuda, M., Rossé, C., and Camonis, J. (2011) SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility. Mol. Cell 42, 650-661
-
(2011)
Mol. Cell
, vol.42
, pp. 650-661
-
-
Parrini, M.C.1
Sadou-Dubourgnoux, A.2
Aoki, K.3
Kunida, K.4
Biondini, M.5
Hatzoglou, A.6
Poullet, P.7
Formstecher, E.8
Yeaman, C.9
Matsuda, M.10
Rossé, C.11
Camonis, J.12
-
51
-
-
0036724188
-
Activation of Rac and Cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells
-
Itoh, R. E., Kurokawa, K., Ohba, Y., Yoshizaki, H., Mochizuki, N., and Matsuda, M. (2002) Activation of Rac and Cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol. Cell. Biol. 22, 6582-6591
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6582-6591
-
-
Itoh, R.E.1
Kurokawa, K.2
Ohba, Y.3
Yoshizaki, H.4
Mochizuki, N.5
Matsuda, M.6
-
52
-
-
0035963331
-
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1
-
DOI 10.1038/35082594
-
Mochizuki, N., Yamashita, S., Kurokawa, K., Ohba, Y., Nagai, T., Miyawaki, A., and Matsuda, M. (2001) Spatio-temporal images of growth-factor- induced activation of Ras and Rap1. Nature 411, 1065-1068 (Pubitemid 32612332)
-
(2001)
Nature
, vol.411
, Issue.6841
, pp. 1065-1068
-
-
Mochizuki, N.1
Yamashita, S.2
Kurokawa, K.3
Ohba, Y.4
Nagai, T.5
Miyawaki, A.6
Matsuda, M.7
-
53
-
-
2542476025
-
Ra1A activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells
-
DOI 10.1091/mbc.E03-11-0857
-
Takaya, A., Ohba, Y., Kurokawa, K., and Matsuda, M. (2004) RalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells. Mol. Biol. Cell 15, 2549-2557 (Pubitemid 38691846)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.6
, pp. 2549-2557
-
-
Takaya, A.1
Ohba, Y.2
Kurokawa, K.3
Matsuda, M.4
-
54
-
-
0042672950
-
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes
-
DOI 10.1083/jcb.200212049
-
Yoshizaki, H., Ohba, Y., Kurokawa, K., Itoh, R. E., Nakamura, T., Mochizuki, N., Nagashima, K., and Matsuda, M. (2003) Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J. Cell Biol. 162, 223-232 (Pubitemid 36928836)
-
(2003)
Journal of Cell Biology
, vol.162
, Issue.2
, pp. 223-232
-
-
Yoshizaki, H.1
Ohba, Y.2
Kurokawa, K.3
Itoh, R.E.4
Nakamura, T.5
Mochizuki, N.6
Nagashima, K.7
Matsuda, M.8
-
55
-
-
0029898330
-
Fluorescence resonance energy transfer between blue-emitting and red-shifted excitation derivatives of the green fluorescent protein
-
DOI 10.1016/0378-1119(95)00768-7
-
Mitra, R. D., Silva, C. M., and Youvan, D. C. (1996) Fluorescence resonance energy transfer between blue-emitting and red-shifted excitation derivatives of the green fluorescent protein. Gene 173, 13-17 (Pubitemid 26239674)
-
(1996)
Gene
, vol.173
, Issue.1
, pp. 13-17
-
-
Mitra, R.D.1
Silva, C.M.2
Youvan, D.C.3
-
56
-
-
56149118852
-
Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells
-
Zaoui, K., Honoré, S., Isnardon, D., Braguer, D., and Badache, A. (2008) Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells. J. Cell Biol. 183, 401-408
-
(2008)
J. Cell Biol.
, vol.183
, pp. 401-408
-
-
Zaoui, K.1
Honoré, S.2
Isnardon, D.3
Braguer, D.4
Badache, A.5
-
57
-
-
0036308458
-
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
-
DOI 10.1038/ncb810
-
Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G., and Bourne, H. R. (2002) Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nat. Cell Biol. 4, 513-518 (Pubitemid 34752437)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.7
, pp. 513-518
-
-
Wang, F.1
Herzmark, P.2
Weiner, O.D.3
Srinivasan, S.4
Servant, G.5
Bourne, H.R.6
-
58
-
-
0036308972
-
A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
-
Weiner, O. D., Neilsen, P. O., Prestwich, G. D., Kirschner, M. W., Cantley, L. C., and Bourne, H. R. (2002) A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat. Cell Biol. 4, 509-513
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 509-513
-
-
Weiner, O.D.1
Neilsen, P.O.2
Prestwich, G.D.3
Kirschner, M.W.4
Cantley, L.C.5
Bourne, H.R.6
-
59
-
-
78651420805
-
Cell behaviors regulated by guidance cues in collective migration of border cells
-
Poukkula, M., Cliffe, A., Changede, R., and Rørth, P. (2011) Cell behaviors regulated by guidance cues in collective migration of border cells. J. Cell Biol. 192, 513-524
-
(2011)
J. Cell Biol.
, vol.192
, pp. 513-524
-
-
Poukkula, M.1
Cliffe, A.2
Changede, R.3
Rørth, P.4
-
60
-
-
78651454152
-
Whence directionality. Guidance mechanisms in solitary and collective cell migration
-
Rørth, P. (2011) Whence directionality. Guidance mechanisms in solitary and collective cell migration. Dev Cell 20, 9-18
-
(2011)
Dev Cell
, vol.20
, pp. 9-18
-
-
Rørth, P.1
-
61
-
-
0037138385
-
The spectrin repeat: A structural platform for cytoskeletal protein assemblies
-
DOI 10.1016/S0014-5793(01)03304-X, PII S001457930103304X
-
Djinovic-Carugo, K., Gautel, M., Ylänne, J., and Young, P. (2002) The spectrin repeat. A structural platform for cytoskeletal protein assemblies. FEBS Lett. 513, 119-123 (Pubitemid 34242988)
-
(2002)
FEBS Letters
, vol.513
, Issue.1
, pp. 119-123
-
-
Djinovic-Carugo, K.1
Gautel, M.2
Ylanne, J.3
Young, P.4
-
62
-
-
53249137803
-
Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling
-
Upadhyay, G., Goessling, W., North, T. E., Xavier, R., Zon, L. I., and Yajnik, V. (2008) Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling. Oncogene 27, 5845-5855
-
(2008)
Oncogene
, vol.27
, pp. 5845-5855
-
-
Upadhyay, G.1
Goessling, W.2
North, T.E.3
Xavier, R.4
Zon, L.I.5
Yajnik, V.6
-
63
-
-
84855968904
-
Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly
-
Namekata, K., Harada, C., Guo, X., Kimura, A., Kittaka, D., Watanabe, H., and Harada, T. (2012) Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly. J. Neurosci. 32, 264-274
-
(2012)
J. Neurosci.
, vol.32
, pp. 264-274
-
-
Namekata, K.1
Harada, C.2
Guo, X.3
Kimura, A.4
Kittaka, D.5
Watanabe, H.6
Harada, T.7
-
64
-
-
0038457895
-
Regulation of leading edge microtubule and actin dynamics downstream of Rac1
-
DOI 10.1083/jcb.200303082
-
Wittmann, T., Bokoch, G. M., and Waterman-Storer, C. M. (2003) Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J. Cell Biol. 161, 845-851 (Pubitemid 36718418)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.5
, pp. 845-851
-
-
Wittmann, T.1
Bokoch, G.M.2
Waterman-Storer, C.M.3
-
65
-
-
33748577718
-
The Rac Activator DOCK7 Regulates Neuronal Polarity through Local Phosphorylation of Stathmin/Op18
-
DOI 10.1016/j.neuron.2006.07.020, PII S089662730600585X
-
Watabe-Uchida, M., John, K. A., Janas, J. A., Newey, S. E., and Van Aelst, L. (2006) The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron 51, 727-739 (Pubitemid 44374902)
-
(2006)
Neuron
, vol.51
, Issue.6
, pp. 727-739
-
-
Watabe-Uchida, M.1
John, K.A.2
Janas, J.A.3
Newey, S.E.4
Van Aelst, L.5
|