-
1
-
-
0030978351
-
Betacatenin is a target for the ubiquitin-proteasome pathway
-
Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. (1997). Betacatenin is a target for the ubiquitin-proteasome pathway. Embo J 16: 3797-3804.
-
(1997)
Embo J
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
2
-
-
0036571011
-
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: A molecular switch for the Wnt pathway
-
Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M et al. (2002). Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev 16: 1066-1076.
-
(2002)
Genes Dev
, vol.16
, pp. 1066-1076
-
-
Amit, S.1
Hatzubai, A.2
Birman, Y.3
Andersen, J.S.4
Ben-Shushan, E.5
Mann, M.6
-
3
-
-
36849066434
-
A novel role of Rac1 GTPase in JCV T-antigen-mediated beta-catenin stabilization
-
Bhattacharyya R, Noch EK, Khalili K. (2007). A novel role of Rac1 GTPase in JCV T-antigen-mediated beta-catenin stabilization. Oncogene 26: 7628-7636.
-
(2007)
Oncogene
, vol.26
, pp. 7628-7636
-
-
Bhattacharyya, R.1
Noch, E.K.2
Khalili, K.3
-
4
-
-
0036049869
-
GEF without a Dbl domain?
-
Braga VM. (2002). GEF without a Dbl domain? Nat Cell Biol 4: E188-E190.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Braga, V.M.1
-
5
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, Tosello-Trampont AC et al. (2002). Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol 4: 574-582.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
-
6
-
-
0842281652
-
Rho and rac take center stage
-
Burridge K, Wennerberg K. (2004). Rho and rac take center stage. Cell 116: 167-179.
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
7
-
-
33644967242
-
Wnt signaling: Complexity at the surface
-
Cadigan KM, Liu YI. (2006). Wnt signaling: complexity at the surface. J Cell Sci 119: 395-402.
-
(2006)
J Cell Sci
, vol.119
, pp. 395-402
-
-
Cadigan, K.M.1
Liu, Y.I.2
-
8
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
9
-
-
23144450821
-
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
-
Cote JF, Motoyama AB, Bush JA, Vuori K. (2005). A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling. Nat Cell Biol 7: 797-807.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 797-807
-
-
Cote, J.F.1
Motoyama, A.B.2
Bush, J.A.3
Vuori, K.4
-
10
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Cote JF, Vuori K. (2002). Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J Cell Sci 115: 4901-4913.
-
(2002)
J Cell Sci
, vol.115
, pp. 4901-4913
-
-
Cote, J.F.1
Vuori, K.2
-
11
-
-
0037081272
-
A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development
-
Dorsky RI, Sheldahl LC, Moon RT. (2002). A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development. Dev Biol 241: 229-237.
-
(2002)
Dev Biol
, vol.241
, pp. 229-237
-
-
Dorsky, R.I.1
Sheldahl, L.C.2
Moon, R.T.3
-
12
-
-
8844264528
-
Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation
-
Esufali S, Bapat B. (2004). Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation. Oncogene 23: 8260-8271.
-
(2004)
Oncogene
, vol.23
, pp. 8260-8271
-
-
Esufali, S.1
Bapat, B.2
-
13
-
-
10744223552
-
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
-
Grimsley CM, Kinchen JM, Tosello-Trampont AC, Brugnera E, Haney LB, Lu M et al. (2003). Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration. J Biol Chem 279: 6087-6097.
-
(2003)
J Biol Chem
, vol.279
, pp. 6087-6097
-
-
Grimsley, C.M.1
Kinchen, J.M.2
Tosello-Trampont, A.C.3
Brugnera, E.4
Haney, L.B.5
Lu, M.6
-
14
-
-
4344562126
-
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
-
Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI. (2004). Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol Cell 15: 511-521.
-
(2004)
Mol Cell
, vol.15
, pp. 511-521
-
-
Ha, N.C.1
Tonozuka, T.2
Stamos, J.L.3
Choi, H.J.4
Weis, W.I.5
-
15
-
-
0037439138
-
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
-
Habas R, Dawid IB, He X. (2003). Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 17: 295-309.
-
(2003)
Genes Dev
, vol.17
, pp. 295-309
-
-
Habas, R.1
Dawid, I.B.2
He, X.3
-
16
-
-
2342477161
-
Signalling activity of beta-catenin targeted to different subcellular compartments
-
Hagen T, Sethi JK, Foxwell N, Vidal-Puig A. (2004). Signalling activity of beta-catenin targeted to different subcellular compartments. Biochem J 379: 471-477.
-
(2004)
Biochem J
, vol.379
, pp. 471-477
-
-
Hagen, T.1
Sethi, J.K.2
Foxwell, N.3
Vidal-Puig, A.4
-
17
-
-
0032492954
-
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
-
Hart MJ, De los Santos R, Albert IN, Rubinfeld B, Polakis P. (1998). Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol 8: 573-581.
-
(1998)
Curr Biol
, vol.8
, pp. 573-581
-
-
Hart, M.J.1
De los Santos, R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
18
-
-
0038275800
-
Regulation of the Wnt signaling pathway by disabled-2 (Dab2)
-
Hocevar BA, Mou F, Rennolds JL, Morris SM, Cooper JA, Howe PH. (2003). Regulation of the Wnt signaling pathway by disabled-2 (Dab2). Embo J 22: 3084-3094.
-
(2003)
Embo J
, vol.22
, pp. 3084-3094
-
-
Hocevar, B.A.1
Mou, F.2
Rennolds, J.L.3
Morris, S.M.4
Cooper, J.A.5
Howe, P.H.6
-
19
-
-
0030923587
-
Beta-catenin mutations in cell lines established from human colorectal cancers
-
Ilyas M, Tomlinson IP, Rowan A, Pignatelli M, Bodmer WF. (1997). Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci USA 94: 10330-10334.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10330-10334
-
-
Ilyas, M.1
Tomlinson, I.P.2
Rowan, A.3
Pignatelli, M.4
Bodmer, W.F.5
-
20
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope RS, Johnson GV. (2004). The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 29: 95-102.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
21
-
-
4043052971
-
Epithelial-mesenchymal transitions: Twist in development and metastasis
-
Kang Y, Massague J. (2004). Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118: 277-279.
-
(2004)
Cell
, vol.118
, pp. 277-279
-
-
Kang, Y.1
Massague, J.2
-
22
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
Katoh H, Negishi M. (2003). RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424: 461-464.
-
(2003)
Nature
, vol.424
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
-
23
-
-
33845351956
-
Beta-catenin destruction complex: Insights and questions from a structural perspective
-
Kimelman D, Xu W. (2006). Beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene 25: 7482-7491.
-
(2006)
Oncogene
, vol.25
, pp. 7482-7491
-
-
Kimelman, D.1
Xu, W.2
-
25
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J et al. (2007). Augmented Wnt signaling in a mammalian model of accelerated aging. Science 317: 803-806.
-
(2007)
Science
, vol.317
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
Liu, J.4
Cao, L.5
Chen, J.6
-
26
-
-
27844516613
-
Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
-
Liu X, Rubin JS, Kimmel AR. (2005). Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Curr Biol 15: 1989-1997.
-
(2005)
Curr Biol
, vol.15
, pp. 1989-1997
-
-
Liu, X.1
Rubin, J.S.2
Kimmel, A.R.3
-
27
-
-
13944277113
-
A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs
-
Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J et al. (2005). A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs. Curr Biol 15: 371-377.
-
(2005)
Curr Biol
, vol.15
, pp. 371-377
-
-
Lu, M.1
Kinchen, J.M.2
Rossman, K.L.3
Grimsley, C.4
Hall, M.5
Sondek, J.6
-
28
-
-
33947600085
-
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex
-
Luo W, Peterson A, Garcia BA, Coombs G, Kofahl B, Heinrich R et al. (2007). Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. Embo J 26: 1511-1521.
-
(2007)
Embo J
, vol.26
, pp. 1511-1521
-
-
Luo, W.1
Peterson, A.2
Garcia, B.A.3
Coombs, G.4
Kofahl, B.5
Heinrich, R.6
-
29
-
-
26644457897
-
hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequency
-
Lyman Gingerich J, Westfall TA, Slusarski DC, Pelegri F. (2005). hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequency. Dev Biol 286: 427-439.
-
(2005)
Dev Biol
, vol.286
, pp. 427-439
-
-
Lyman Gingerich, J.1
Westfall, T.A.2
Slusarski, D.C.3
Pelegri, F.4
-
30
-
-
36849055111
-
SnapShot: Wnt/beta-catenin signaling
-
Macdonald BT, Semenov MV, He X. (2007). SnapShot: Wnt/beta-catenin signaling. Cell 131: 1204.
-
(2007)
Cell
, vol.131
, pp. 1204
-
-
Macdonald, B.T.1
Semenov, M.V.2
He, X.3
-
31
-
-
33646241997
-
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
-
Mikels AJ, Nusse R. (2006). Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4: e115.
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
32
-
-
0037205007
-
The promise and perils of Wnt signaling through beta-catenin
-
Moon RT, Bowerman B, Boutros M, Perrimon N. (2002). The promise and perils of Wnt signaling through beta-catenin. Science 296: 1644-1646.
-
(2002)
Science
, vol.296
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
33
-
-
28944448921
-
Molecular genetics of Axis formation in zebrafish
-
Schier AF, Talbot WS. (2005). Molecular genetics of Axis formation in zebrafish. Annu Rev Genet 39: 561-613.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 561-613
-
-
Schier, A.F.1
Talbot, W.S.2
-
34
-
-
18844412965
-
Wnt/beta-catenin regulation of the Sp1-related transcription factor sp5l promotes tail development in zebrafish
-
Thorpe CJ, Weidinger G, Moon RT. (2005). Wnt/beta-catenin regulation of the Sp1-related transcription factor sp5l promotes tail development in zebrafish. Development 132: 1763-1772.
-
(2005)
Development
, vol.132
, pp. 1763-1772
-
-
Thorpe, C.J.1
Weidinger, G.2
Moon, R.T.3
-
35
-
-
0041695485
-
A second canon functions and mechanisms of beta-catenin-independent Wnt signaling
-
Veeman MT, Axelrod JD, Moon RT. (2003). A second canon functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 5: 367-377.
-
(2003)
Dev Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
36
-
-
0033565533
-
Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex
-
Willert K, Shibamoto S, Nusse R. (1999). Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev 13: 1768-1773.
-
(1999)
Genes Dev
, vol.13
, pp. 1768-1773
-
-
Willert, K.1
Shibamoto, S.2
Nusse, R.3
-
37
-
-
33847268280
-
Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration
-
Wu B, Crampton SP, Hughes CC. (2007). Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 26: 227-239.
-
(2007)
Immunity
, vol.26
, pp. 227-239
-
-
Wu, B.1
Crampton, S.P.2
Hughes, C.C.3
-
38
-
-
41949105179
-
Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
-
Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F. (2008). Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 133: 340-353.
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
Hilton, M.J.4
Williams, D.A.5
Long, F.6
-
39
-
-
0344442773
-
Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex
-
Xing Y, Clements WK, Kimelman D, Xu W. (2003). Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev 17: 2753-2764.
-
(2003)
Genes Dev
, vol.17
, pp. 2753-2764
-
-
Xing, Y.1
Clements, W.K.2
Kimelman, D.3
Xu, W.4
-
40
-
-
0037423929
-
DOCK4, a GTPase activator, is disrupted during tumorigenesis
-
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC et al. (2003). DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell 112: 673-684.
-
(2003)
Cell
, vol.112
, pp. 673-684
-
-
Yajnik, V.1
Paulding, C.2
Sordella, R.3
McClatchey, A.I.4
Saito, M.5
Wahrer, D.C.6
-
41
-
-
33644963622
-
An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C)
-
Yan D, Li F, Hall ML, Sage C, Hu WH, Giallourakis C et al. (2006). An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C). J Mol Biol 357: 755-764.
-
(2006)
J Mol Biol
, vol.357
, pp. 755-764
-
-
Yan, D.1
Li, F.2
Hall, M.L.3
Sage, C.4
Hu, W.H.5
Giallourakis, C.6
-
42
-
-
33745809820
-
APC differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
-
Yang J, Zhang W, Evans PM, Chen X, He X, Liu C. (2006). APC differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 281: 17751-17757.
-
(2006)
J Biol Chem
, vol.281
, pp. 17751-17757
-
-
Yang, J.1
Zhang, W.2
Evans, P.M.3
Chen, X.4
He, X.5
Liu, C.6
-
43
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT. (1996). The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 10: 1443-1454.
-
(1996)
Genes Dev
, vol.10
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
44
-
-
28644439005
-
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R et al. (2005). A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438: 873-877.
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
Li, S.4
Huang, H.5
Habas, R.6
|