In vivo activation of azipropofol prolongs anesthesia and reveals synaptic targets

Journal of Biological Chemistry

Volumn 288, Issue 2, 2013, Pages 1279-1285

  Weiser, Brian P ^a   Kelz, Max B ^a   Eckenhoff, Roderic G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PARTNERS; IN-VIVO; MOLECULAR MECHANISM; PHOTOACTIVATION; PHOTOLABELS; PROPOFOL; PROTEIN BINDING PARTNERS; PROTEOMICS; TIME-RESOLVED; VOLTAGE-DEPENDENT ANION CHANNELS; XENOPUS LAEVIS TADPOLES;

BIOCHEMISTRY; MOLECULAR BIOLOGY;

ANESTHETICS;

ANESTHETIC AGENT; AZIPROPOFOL; MEMBRANE PROTEIN; PROPOFOL; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL;

ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; COVALENT BOND; DRUG PROTEIN BINDING; DRUG TARGETING; GENERAL ANESTHESIA; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR MECHANICS; NERVE CELL MEMBRANE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHOTOACTIVATION; PHOTOAFFINITY LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEOMICS; SYNAPTIC TRANSMISSION; TANDEM MASS SPECTROMETRY; XENOPUS LAEVIS;

ANESTHETICS, INTRAVENOUS; ANIMALS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ISOELECTRIC FOCUSING; LARVA; MASS SPECTROMETRY; PROPOFOL; SYNAPSES; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 84872304392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.413989     Document Type: Article

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