Etanercept attenuates collagen-induced arthritis by modulating the association between BAFFR expression and the production of splenic memory B cells

Pharmacological Research

Volumn 68, Issue 1, 2013, Pages 38-45

  Wang, Qing Tong ^a   Wu, Yu Jing ^a   Huang, Bei ^a   Ma, Yu Kun ^a   Song, Shan Shan ^a   Zhang, Ling Ling ^a   Chen, Jing Yu ^a   Wu, Hua Xun ^a   Sun, Wu Yi ^a   Wei, Wei ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

BAFFR; Collagen induced arthritis; Etanercept; Memory B cells

Indexed keywords

B CELL ACTIVATING FACTOR RECEPTOR; CD27 ANTIGEN; ETANERCEPT; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; METHOTREXATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL ASSAY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; HISTOPATHOLOGY; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RECEPTOR UPREGULATION;

ANIMALS; ANTIGENS, CD27; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; B-CELL ACTIVATION FACTOR RECEPTOR; B-LYMPHOCYTES; CELL PROLIFERATION; COLLAGEN TYPE II; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; MALE; MICE; MICE, INBRED DBA; RECEPTORS, TUMOR NECROSIS FACTOR; SPLEEN;

EID: 84872299740     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.11.003     Document Type: Article

References (32)

1. S. Ramos-Romero, F.J. Pérez-Cano, E. Ramiro-Puig, A. Franch, and M. Castell Cocoa intake attenuates oxidative stress associated with rat adjuvant arthritis Pharmacological Research 66 2012 207 212
2. Q.T. Wang, L.L. Zhang, H.X. Wu, and W. Wei The expression change of β-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effects of total glucosides of paeony Journal of Ethnopharmacology 133 2011 511 516
3. C.M. Weyand, E. Bryl, and J.J. Goronzy The role of T cells in rheumatoid arthritis Archivum Immunologiae et Therapiae Experimentalis (Warsz) 48 2000 429 435
4. A.P. Cope T cells in rheumatoid arthritis Arthritis Research and Therapy 10 2008 S1
5. S. Takemura, P.A. Klimiuk, A. Braun, J.J. Goronzy, and C.M. Weyand T cell activation in rheumatoid synovium is B cell dependent Journal of Immunology 167 2001 4710 4718
6. Q.T. Wang, Y.K. Ma, B. Huang, D.D. Liu, and W. Wei Effect of rhTACI-Ig fusion protein on antigen-specific T cell responses from keyhole limpet haemocyanin challenged mice Molecular Immunology 49 2011 380 386
7. T. Vallerskog, M. Heimbürger, I. Gunnarsson, W. Zhou, M. Wahren-Herlenius, and C. Trollmo Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis Arthritis Research and Therapy 8 2006 R167
8. P.C. Taylor Rituximab in the treatment of rheumatoid arthritis Expert Review of Clinical Immunology 3 2007 17 26
9. Y. Tanaka Intensive treatment and treatment holiday of TNF-inhibitors in rheumatoid arthritis Current Opinion in Rheumatology 24 2012 319 326
10. M.J. Leandro Anti-tumour necrosis factor therapy and B cells in rheumatoid arthritis Arthritis Research and Therapy 11 2009 128
11. M.M. Souto-Carneiro, V. Mahadevan, K. Takada, R. Fritsch-Stork, T. Nanki, and M. Brown Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumor necrosis factor Arthritis Research and Therapy 11 2009 R84
12. A. Bendele Animal models of rheumatoid arthritis Journal of Musculoskeletal & Neuronal Interactions 1 2001 377 385
13. K.W. Hunter Jr., R.A. Gault, J.S. Stehouwer, and S.W. Tam-Chang Synthesis of cetyl myristoleate and evaluation of its therapeutic efficacy in a murine model of collagen-induced arthritis Pharmacological Research 47 2003 43 47
14. P.P. Li, D.D. Liu, Y.J. Liu, S.S. Song, Q.T. Wang, and Y. Chang BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin Journal of Ethnopharmacology 141 2012 290 300
15. D. Wang, Y. Chang, Y. Wu, L. Zhang, S. Yan, and G. Xie Therapeutic effects of TACI-Ig on rat with adjuvant arthritis Clinical & Experimental Immunology 163 2011 225 234
16. Y. Liu, L. Zhang, Y. Wu, T. Tong, W. Zhao, and P. Li Therapeutic effects of TACI-Ig on collagen-induced arthritis by regulating T and B lymphocytes function in DBA/1 mice European Journal of Pharmacology 654 2011 304 314
17. Y. Chang, Y. Wu, D. Wang, W. Wei, Q. Qin, and G. Xie Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via attenuating inflammatory responses Rheumatology 50 2011 862 870
18. T.A. Kerensky, A.B. Gottlieb, S. Yaniv, and S.C. Au Etanercept: efficacy and safety for approved indications Expert Opinion on Drug Safety 11 2012 121 139
19. R. Saraceno, C. Schipani, A. Mazzotta, M. Esposito, L. Di Renzo, and A. De Lorenzo Effect of anti-tumor necrosis factor-alpha therapies on body mass index in patients with psoriasis Pharmacological Research 57 2008 290 295
20. J. Zou, M. Rudwaleit, J. Brandt, A. Thiel, J. Braun, and J. Sieper Up regulation of the production of tumour necrosis factor α and interferon γ by T cells in ankylosing spondylitis during treatment with etanercept Annals of the Rheumatic Diseases 62 2003 561 564
21. F. Lange, E. Bajtner, C. Rintisch, K.S. Nandakumar, U. Sack, and R. Holmdahl Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis Annals of the Rheumatic Diseases 64 2005 599 605
22. M.F. Neurath, K. Hildner, C. Becker, J.F. Schlaak, K. Barbulescu, and T. Germann Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): a mechanism for methotrexate-mediated immunosuppression Clinical & Experimental Immunology 115 1999 42 55
23. U. Klein, and R. Dalla-Favera Germinal centres: role in B-cell physiology and malignancy Nature Reviews Immunology 8 2008 22 33
24. C. Mauri, and E.C. Jury Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis? Arthritis Research and Therapy 12 2010 133
25. P. Engel, J.A. Gómez-Puerta, M. Ramos-Casals, F. Lozano, and X. Bosch Therapeutic targeting of B cells for rheumatic autoimmune diseases Pharmacological Reviews 63 2011 127 156
26. A. Fekete, L. Soos, Z. Szekanecz, Z. Szabo, P. Szodoray, and S. Barath Disturbances in B- and T-cell homeostasis in rheumatoid arthritis: suggested relationships with antigen-driven immune responses Journal of Autoimmunity 29 2007 154 163
27. V. Kalia, S. Sarkar, T.S. Gourley, B.T. Rouse, and R. Ahmed Differentiation of memory B and T cells Current Opinion in Immunology 18 2006 255 264
28. M. Rauch, R. Tussiwand, N. Bosco, and A.G. Rolink Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells PLoS ONE 4 2009 e5456
29. J.R. Darce, B.K. Arendt, S.K. Chang, and D.F. Jelinek Divergent effects of BAFF on human memory B cell differentiation into Ig-secreting cells The Journal of Immunology 178 2007 5612 5622
30. D.T. Avery, S.L. Kalled, J.I. Ellyard, C. Ambrose, S.A. Bixler, and M. Thien BAFF selectively enhances the survival of plasmablasts generated from human memory B cells The Journal of Clinical Investigation 112 2003 286 297
31. I. de la Torre, R.A. Moura, M.J. Leandro, J. Edwards, and G. Cambridge B-cell-activating factor receptor expression on naive and memory B cells: relationship with relapse in patients with rheumatoid arthritis following B-cell depletion therapy Annals of the Rheumatic Diseases 69 2010 2181 2188
32. + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells The Journal of Experimental Medicine 188 1998 1679 1689