Therapeutic effects of TACI-Ig on collagen-induced arthritis by regulating T and B lymphocytes function in DBA/1 mice

European Journal of Pharmacology

Volumn 654, Issue 3, 2011, Pages 304-314

  Liu, Yunjie ^a   Zhang, Lingling ^a   Wu, Yingqi ^a   Tong, Tong ^a   Zhao, Wendi ^a   Li, Peipei ^a   Huang, Min ^b   Wang, Wenxiang ^b   Fang, Jianmin ^c   Wei, Wei ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Yantai Rongchang Biotechnologies Ltd   (China)

^c TONGJI UNIVERSITY   (China)

Author keywords

B lymphocyte stimulator; Collagen induced arthritis; Lymphocyte; Rheumatoid arthritis; TACI Ig

Indexed keywords

ATACICEPT; B CELL ACTIVATING FACTOR; COLLAGEN; IMMUNOGLOBULIN FC FRAGMENT; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DBA 1 MOUSE; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HISTOPATHOLOGY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNITY; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CELL PROLIFERATION; DINOPROSTONE; JOINTS; MALE; MICE; RECOMBINANT FUSION PROTEINS; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; THYMUS GLAND;

EID: 79951669773     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.01.002     Document Type: Article

References (47)

1. J. Bilsborough, E. Chadwick, S. Mudri, X. Ye, W.R. Henderson, K. Waggie, L. Hebb, J. Shin, M. Rixon, J.A. Gross, and S.R. Dillon TACI-Ig prevents the development of airway hyperresponsiveness in a murine model of asthma Clin. Exp. Allergy 38 2008 1959 1968
2. D.D. Brand, A.H. Kang, and E.F. Rosloniec Immunopathogenesis of collagen arthritis Springer Semin. Immunopathol. 25 2003 3 18 (Pubitemid 37000035)
3. M. Carbonatto, P. Yu, M. Bertolino, E. Vigna, S. Steidler, L. Fava, C. Daghero, B. Roattino, M. Onidi, M. Ardizzone, S. Peano, J. Visich, D. Janszen, S. Dillon, and R. Ponce Nonclinical safety, pharmacokinetics, and pharmacodynamics of atacicept Toxicol. Sci. 105 2008 200 210
4. G.S. Cheema, V. Roschke, D.M. Hilbert, and W. Stohl Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases Arthritis Rheum. 44 2001 1313 1319 (Pubitemid 32537529)
5. S. Cuzzocrea, E. Mazzon, C. Bevilaqua, G. Costantino, D. Britti, G. Mazzullo, A. De Sarro, and A.P. Caputi Cloricromene, a coumarine derivative, protects against collagen-induced arthritis in Lewis rats Br. J. Pharmacol. 131 2000 1399 1407
6. I. Debnath, K.M. Roundy, J.J. Weis, and J.H. Weis Analysis of the regulatory role of BAFF in controlling the expression of CD21 and CD23 Mol. Immunol. 44 2007 2388 2399 (Pubitemid 46097107)
7. C. Ding Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases Expert Opin. Biol. Ther. 8 2008 1805 1814
8. P. Engel, L. Zhou, D.C. Ord, S. Sato, B. Koller, and T.F. Tedder Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule Immunity 3 1995 39 50
9. H. Gao, A. Bian, Y. Zheng, R. Li, Q. Ji, G. Huang, D. Hu, L. Zhang, W. Gong, Y. Hu, and F. He sBAFF mutants induce neutralizing antibodies against BAFF FEBS Lett. 581 2007 581 586 (Pubitemid 46216282)
10. L. Gorelik, A.H. Cutler, G. Thill, S.D. Miklasz, D.E. Shea, C. Ambrose, S.A. Bixler, L. Su, M.L. Scott, and S.L. Kalled Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function J. Immunol. 172 2004 762 766 (Pubitemid 38113731)
11. J.E. Gottenberg, M. Busson, J. Cohen-Solal, F. Lavie, K. Abbed, R.P. Kimberly, J. Sibilia, and X. Mariette Correlation of serum B lymphocyte stimulator and β2 microglobulin with autoantibody secretion and systemic involvement in primary Sjögren's syndrome Ann. Rheum. Dis. 64 2005 1050 1055 (Pubitemid 40909521)
12. D. Gray, and P. Matzinger T cell memory is short-lived in the absence of antigen J. Exp. Med. 174 1991 969 974
13. J.A. Gross, S.R. Dillon, S. Mudri, J. Johnston, A. Littau, R. Roque, M. Rixon, O. Schou, K.P. Foley, H. Haugen, S. McMillen, K. Waggie, R.W. Schreckhise, K. Shoemaker, T. Vu, M. Moore, A. Grossman, and C.H. Clegg TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS Immunity 15 2001 289 302 (Pubitemid 32816877)
14. S. Ju, D. Zhang, Y. Wang, H. Ni, X. Kong, and R. Zhong Correlation of the expression levels of BLyS and its receptors mRNA in patients with systemic lupus erythematosus Clin. Biochem. 39 2006 1131 1137 (Pubitemid 44838576)
15. S. Ju, Y. Wang, H. Ni, X. Wang, P. Jiang, X. Kong, and R. Zhong Correlation of expression levels of BLyS and its receptors with multiple myeloma Clin. Biochem. 42 2009 387 399
16. M. Kapoor, F. Kojima, M. Qian, L. Yang, and L.J. Crofford Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis FASEB J. 20 2006 2387 2389
17. S.D. Khare, I. Sarosi, X.Z. Xia, S. McCabe, K. Miner, I. Solovyev, N. Hawkins, M. Kelley, D. Chang, G. Van, L. Ross, J. Delaney, L. Wang, D. Lacey, W.J. Boyle, and H. Hsu Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice Proc. Natl Acad. Sci. USA 97 2009 3370 3375
18. Y.H. Kim, B.H. Choi, H.G. Cheon, and M.S. Do B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation Exp. Mol. Med. 41 2009 208 216
19. F. Kojima, H. Naraba, Y. Sasaki, R. Okamoto, T. Koshino, and S. Kawai Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells J. Rheumatol. 29 2002 1836 1842 (Pubitemid 34988689)
20. F. Kojima, S. Kato, and S. Kawai Prostaglandin E synthase in the pathophysiology of arthritis Fundam. Clin. Pharmacol. 19 2005 255 261 (Pubitemid 40769448)
21. F. Kojima, M. Kapoor, S. Kawai, L. Yang, D.M. Aronoff, and L.J. Crofford Prostaglandin E2 activates RAP1 via EP2/EP4 receptors and cAMP-signaling in rheumatoid synovial fibroblasts: involvement of EPAC1 and PKA: the regulation of Rap1 by PGE2 in RSF Prostaglandins Other Lipid Mediat. 89 2009 26 33
22. S. Li, A. Lu, B. Li, and Y. Wang Circadian rhythms on hypothalamic-pituitary-adrenal axis hormones and cytokines of collagen induced arthritis in rats J. Autoimmun. 22 2004 277 285 (Pubitemid 38543219)
23. W. Lu, P. Cao, X. Cai, J. Yu, C. Hu, M. Cao, and S. Zhang Molecular cloning, expression, and bioactivity of dove B lymphocyte stimulator (doBAFF) Vet. Immunol. Immunopathol. 128 2009 374 380
24. + T cells Arthritis Rheum. 46 2002 1671 1682 (Pubitemid 34620216)
25. L. Mandik-Nayak, N. Ridge, M. Fields, A.Y. Park, and J. Erikson Role of B cells in systemic lupus erythematosus and rheumatoid arthritis Curr. Opin. Immunol. 20 2008 639 645
26. L. Martinez-Gamboa, H.P. Brezinschek, G.R. Burmester, and T. Dörner Immunopathologic role of B lymphocytes in rheumatoid arthritis Autoimmun. Rev. 5 2006 437 442
27. + cell depletion hastens the onset of severe disease in collagen-induced arthritis Arthritis Rheum. 48 2003 1452 1460 (Pubitemid 36554546)
28. + regulatory T cells Arthritis Rheum. 52 2005 2212 2221 (Pubitemid 40994344)
29. M. Murakami, H. Naraba, T. Tanioka, N. Semmyo, Y. Nakatani, F. Kojima, T. Ikeda, M. Fueki, A. Ueno, S. Oh, and I. Kudo Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2 J. Biol. Chem. 275 2000 32783 32792
30. M. Murakami, K. Nakashima, D. Kamei, S. Masuda, Y. Ishikawa, T. Ishii, Y. Ohmiya, K. Watanabe, and I. Kudo Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2 J. Biol. Chem. 278 2003 37937 37947 (Pubitemid 37175324)
31. L.M. Nadler, K.C. Anderson, G. Marti, M. Bates, E. Park, J.F. Daley, and S.F. Schlossman B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes J. Immunol. 131 1983 244 250 (Pubitemid 13067888)
32. R. Roque, R. Ponce, F. Burleson, M. Cabrit, H. Broly, and M. Rogge Influenza virus host response of C57Bl/6 mice treated with TACI-Ig Immunopharmacol. Immunotoxicol. 28 2006 13 32 (Pubitemid 43739106)
33. S. Sato, M. Fujimoto, M. Hasegawa, and K. Takehara Altered blood B lymphocyte homeostasis in systemic sclerosis: expanded naive B cells and diminished but activated memory B cells Arthritis Rheum. 50 2004 1918 1927 (Pubitemid 38725103)
34. T.M. Seyler, Y.W. Park, S. Takemura, R.J. Bram, P.J. Kurtin, J.J. Goronzy, and C.M. Weyand BLyS and APRIL in rheumatoid arthritis J. Clin. Invest. 115 2005 3083 3092 (Pubitemid 41567573)
35. D.O. Stichtenoth, S. Thoren, H. Bian, M. Peters-Golden, P.J. Jakobsson, and L.J. Crofford Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells J. Immunol. 167 2001 469 474 (Pubitemid 32567813)
36. P.P. Tak, R.M. Thurlings, C. Rossier, I. Nestorov, A. Dimic, V. Mircetic, M. Rischmueller, E. Nasonov, E. Shmidt, P. Emery, and A. Munafo Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study Arthritis Rheum. 58 2008 61 72
37. T. Tong, W. Zhao, Y.Q. Wu, Y. Chang, Q.T. Wang, L.L. Zhang, and W. Wei Chicken type II collagen induced immune balance of main subtype of helper T cells in mesenteric lymph node lymphocytes in rats with collagen-induced arthritis Inflamm. Res. 59 2010 369 377
38. + regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid Arthritis Rheum. 50 2004 2775 2785 (Pubitemid 39209514)
39. E.M. Vital, and P. Emery The development of targeted therapies in rheumatoid arthritis J. Autoimmun. 31 2008 219 227
40. H. Wang, S.A. Marsters, T. Baker, B. Chan, W.P. Lee, L. Fu, D. Tumas, M. Yan, V.M. Dixit, A. Ashkenazi, and I.S. Grewal TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice Nat. Immunol. 2 2001 632 637 (Pubitemid 32677631)
41. M. Westman, M. Korotkova, E. af Klint, A. Stark, L.P. Audoly, L. Klareskog, A.K. Ulfgren, and P.J. Jakobsson Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium Arthritis Rheum. 50 2004 1774 1780 (Pubitemid 38725089)
42. R.O. Williams, E. Paleolog, and M. Feldmann Cytokine inhibitors in rheumatoid arthritis and other autoimmune diseases Curr. Opin. Pharmacol. 7 2007 412 417 (Pubitemid 47289266)
43. + T cells and the control of autoimmune disease Curr. Opin. Immunol. 16 2004 695 701 (Pubitemid 39423656)
44. S.Y. Xu, R.L. Bian, and X. Chen Methodology of Pharmacological Experiments 3rd Ed 2002 People's Medical Publishing House Beijing 1426 1427
45. H. Xu, L.N. Liew, I.C. Kuo, C.H. Huang, D.L. Goh, and K.Y. Chua The modulatory effects of lipopolysaccharide-stimulated B cells on differential T-cell polarization Immunology 125 2008 218 228
46. + T cell subset is related to Th1/Th2 balance and disease severity in rheumatoid arthritis Arthritis Rheum. 43 2000 617 627 (Pubitemid 30394954)
47. L.L. Zhang, W. Wei, S.X. Yan, X.Y. Hu, and W.Y. Sun Therapeutic effects of glucosides of Cheanomeles speciosa on collagen-induced arthritis in mice Acta Pharmacol. Sin. 25 2004 1495 1501 (Pubitemid 39490896)