Substrate translocation and stimulated ATP hydrolysis of human ABC transporter MRP3 show positive cooperativity and are half-coupled

Biophysical Chemistry

Volumn 171, Issue , 2013, Pages 31-37

  Seelheim, Patrick ^a   Wüllner, Adriane ^a   Galla, Hans Joachim ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

ABC transporter; Cooperativity; Enzyme kinetic; MRP3; Proteoliposomes; Transport mechanism

Indexed keywords

5(6) CARBOXY 2' 7' DICHLOROFLUORESCEIN; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; DICHLOROFLUORESCEIN; MULTIDRUG RESISTANCE PROTEIN 3; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; HUMANS; HYDROLYSIS; KINETICS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84872288353     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2012.10.001     Document Type: Article

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