Functional reconstitution of human ABCC3 into proteoliposomes reveals a transport mechanism with positive cooperativity

Biochemistry

Volumn 48, Issue 20, 2009, Pages 4423-4430

  Zehnpfennig, Britta ^a   Urbatsch, Ina L ^b   Galla, Hans Joachim ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTICANCER DRUG; ATP BINDING CASSETTE TRANSPORTERS; ATP-ASE ACTIVITY; CELL-FREE; COOPERATIVITY; DETAILED KINETICS; ETOPOSIDE; HILL COEFFICIENT; MAXIMUM TRANSPORT; MEMBRANE TRANSPORT PROTEINS; MICROMOLAR RANGE; MILLIMOLAR RANGE; MULTIDRUG RESISTANCE; ORGANIC ANIONS; OVER-EXPRESSION; PHYSIOLOGICAL SUBSTRATE; PICHIA PASTORIS; PROTEOLIPOSOMES; TECHNICAL ADVANCES; TRANSPORT MECHANISM;

BIOCHEMISTRY; CELL MEMBRANES; PROTEINS; PURIFICATION;

SUBSTRATES;

ETOPOSIDE; LEUKOTRIENE C4; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 3;

ARTICLE; CELL FREE SYSTEM; DRUG UPTAKE; GENE OVEREXPRESSION; HUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEOLIPOSOME; TRANSPORT KINETICS;

ALLOSTERIC SITE; CELL-FREE SYSTEM; DETERGENTS; ETOPOSIDE; HUMANS; HYDROLYSIS; KINETICS; LEUKOTRIENE C4; MICROSOMES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PICHIA; PROTEIN BINDING; PROTEOLIPIDS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

PICHIA PASTORIS;

EID: 66149189424     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9001908     Document Type: Article

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