P53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells

Toxicology and Applied Pharmacology

Volumn 267, Issue 1, 2013, Pages 113-124

  Huang, Shi Wei ^a   Wu, Chun Ying ^b   Wang, Yen Ting ^c   Kao, Jun Kai ^a,d   Lin, Chi Chen ^a   Chang, Chia Che ^a   Mu, Szu Wei ^a   Chen, Yu Yu ^a   Chiu, Husan Wen ^e,f   Chang, Chuan Hsun ^c,g   Liang, Shu Mei ^e,f   Chen, Yi Ju ^b   Huang, Jau Ling ^h   Shieh, Jeng Jer ^a,b  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^d CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^f AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^g TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^h CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis and autophagy; Compound C; P53

Indexed keywords

ATM PROTEIN; COMPOUND C; CYCLIN DEPENDENT KINASE 1; ENZYME INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE INHIBITOR; MUTANT PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BASAL CELL CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; M PHASE CELL CYCLE CHECKPOINT; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SKIN CANCER; UPREGULATION; WILD TYPE;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PYRAZOLES; PYRIMIDINES; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

ATAXIA TELANGIECTASIA;

EID: 84872253569     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.12.016     Document Type: Article

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