-
1
-
-
21844462331
-
A multiple scale model for tumor growth
-
T. Alarcón, H. M. Byrne and P. K. Maini, A multiple scale model for tumor growth, Multiscale Modeling and Simulation, 3 (2005), 440-475.
-
(2005)
Multiscale Modeling and Simulation
, vol.3
, pp. 440-475
-
-
Alarcón, T.1
Byrne, H.M.2
Maini, P.K.3
-
2
-
-
34047118103
-
Mathematical models of the VEGF receptor and its role in cancer therapy
-
T. Alarcón and K. M. Page, Mathematical models of the VEGF receptor and its role in cancer therapy, Journal of The Royal Society Interface, 4 (2007), 283-304.
-
(2007)
Journal of the Royal Society Interface
, vol.4
, pp. 283-304
-
-
Alarcón, T.1
Page, K.M.2
-
3
-
-
33750533388
-
Physicochemical modelling of cell signalling pathways
-
B. B. Aldridge, J. M. Burke, D. A. Lauffenburger and P. K. Sorger, Physicochemical modelling of cell signalling pathways, Nature Cell Biology, 8 (2006), 1195-1203.
-
(2006)
Nature Cell Biology
, vol.8
, pp. 1195-1203
-
-
Aldridge, B.B.1
Burke, J.M.2
Lauffenburger, D.A.3
Sorger, P.K.4
-
4
-
-
33745075591
-
Tools for kinetic modeling of biochemical networks
-
R. Alves, F. Antunes and A. Salvador, Tools for kinetic modeling of biochemical networks, Nature Biotechnology, 24 (2006), 667-672.
-
(2006)
Nature Biotechnology
, vol.24
, pp. 667-672
-
-
Alves, R.1
Antunes, F.2
Salvador, A.3
-
5
-
-
0032170064
-
Continuous and discrete mathematical models of tumor-induced angiogenesis
-
A. R. A. Anderson and M. A. J. Chaplain, Continuous and discrete mathematical models of tumor-induced angiogenesis, Bulletin of Mathematical Biology, 60 (1998), 857-899.
-
(1998)
Bulletin of Mathematical Biology
, vol.60
, pp. 857-899
-
-
Anderson, A.R.A.1
Chaplain, M.A.J.2
-
6
-
-
3843079723
-
A history of the study of solid tumour growth: The contribution of mathematical modelling
-
R. P. Araujo and D. L. S McElwain, A history of the study of solid tumour growth: the contribution of mathematical modelling, Bulletin of Mathematical Biology, 66 (2004) 1039-1091.
-
(2004)
Bulletin of Mathematical Biology
, vol.66
, pp. 1039-1091
-
-
Araujo, R.P.1
McElwain, D.L.S.2
-
7
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
U. S. Bhalla, R. Iyengar and others, Emergent properties of networks of biological signaling pathways, Science, 283 (1999), 381-387.
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
8
-
-
33746260079
-
Vascular network remodeling via vessel cooption, regression and growth in tumors
-
K. Bartha and H. Rieger, Vascular network remodeling via vessel cooption, regression and growth in tumors, Journal of Theoretical Biology, 241 (2006), 903-918.
-
(2006)
Journal of Theoretical Biology
, vol.241
, pp. 903-918
-
-
Bartha, K.1
Rieger, H.2
-
9
-
-
70249113326
-
A pharmacologically based multiscale mathematical model of angiogenesis and its use in investigating the efficacy of a new cancer treatment strategy
-
F. Billy, B. Ribba, O. Saut, H. Morre-Trouilhet, T. Colin, D. Bresch, J. P. Boissel, E. Grenier and J. P. Flandrois, A pharmacologically based multiscale mathematical model of angiogenesis and its use in investigating the efficacy of a new cancer treatment strategy, Journal of Theoretical Biology, 260 (2009), 545-562.
-
(2009)
Journal of Theoretical Biology
, vol.260
, pp. 545-562
-
-
Billy, F.1
Ribba, B.2
Saut, O.3
Morre-Trouilhet, H.4
Colin, T.5
Bresch, D.6
Boissel, J.P.7
Grenier, E.8
Flandrois, J.P.9
-
10
-
-
43049177744
-
Modelling methodology in physiopathology
-
J. P. Boissel, B. Ribba, E. Grenier, G. Chapuisat and M-A. Dronne, Modelling methodology in physiopathology, Progress in Biophysics and Molecular Biology, 97 (2008), 28-39.
-
(2008)
Progress in Biophysics and Molecular Biology
, vol.97
, pp. 28-39
-
-
Boissel, J.P.1
Ribba, B.2
Grenier, E.3
Chapuisat, G.4
Dronne, M.-A.5
-
11
-
-
0028790729
-
Growth of nonnecrotic tumors in the presence and absence of inhibitors
-
H. M. Byrne and M. A. J. Chaplain, Growth of nonnecrotic tumors in the presence and absence of inhibitors, Mathematical Biosciences, 130 (1995), 151-181.
-
(1995)
Mathematical Biosciences
, vol.130
, pp. 151-181
-
-
Byrne, H.M.1
Chaplain, M.A.J.2
-
12
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
P. Carmeliet and R. K. Jain, Angiogenesis in cancer and other diseases, Nature, 407 (2000), 249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
13
-
-
33645056182
-
The role of VEGF receptors in angiogenesis; Complex partnerships
-
S. Cebe-Suarez, A. Zehnder-Fjällman and K. Ballmer-Hofer, The role of VEGF receptors in angiogenesis; complex partnerships, Cellular and Molecular Life Sciences, 63 (2006), 601-615.
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, pp. 601-615
-
-
Cebe-Suarez, S.1
Zehnder-Fjällman, A.2
Ballmer-Hofer, K.3
-
15
-
-
0642306485
-
VEGF-receptor signal transduction
-
M. J. Cross, J. Dixelius, T. Matsumoto and L. Claesson-Welsh, VEGF-receptor signal transduction, Trends in Biochemical Sciences, 28 (2003), 488-494.
-
(2003)
Trends in Biochemical Sciences
, vol.28
, pp. 488-494
-
-
Cross, M.J.1
Dixelius, J.2
Matsumoto, T.3
Claesson-Welsh, L.4
-
16
-
-
79953782986
-
Combining epitope-distinct antibodies to HER2: Cooperative inhibitory effects on invasive growth
-
A. Emde, C. R. Pradeep, D. A. Ferraro, N. Ben-Chetrit, M. Sela, B. Ribba, Z. Kam and Y. Yarden, Combining epitope-distinct antibodies to HER2: cooperative inhibitory effects on invasive growth, Oncogene, 30 (2010), 1631-1642.
-
(2010)
Oncogene
, vol.30
, pp. 1631-1642
-
-
Emde, A.1
Pradeep, C.R.2
Ferraro, D.A.3
Ben-Chetrit, N.4
Sela, M.5
Ribba, B.6
Kam, Z.7
Yarden, Y.8
-
17
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
S. Faivre, G. Demetri, W. Sargent and E. Raymond, Molecular basis for sunitinib efficacy and future clinical development, Nature Reviews Drug Discovery, 6 (2007), 734-745.
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
18
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
N. Ferrara, VEGF and the quest for tumour angiogenesis factors, Nature Reviews Cancer, 2 (2002), 795-803.
-
(2002)
Nature Reviews Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
19
-
-
4143136640
-
Vascular endothelial growth factor: Basic science and clinical progress
-
N. Ferrara, Vascular endothelial growth factor: basic science and clinical progress, Endocrine Reviews, 25 (2004), 581-611.
-
(2004)
Endocrine Reviews
, vol.25
, pp. 581-611
-
-
Ferrara, N.1
-
20
-
-
20544455330
-
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
-
N. Ferrara, K. J. Hillan and W. Novotny, Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy, Biochemical and Biophysical Research Communications, 333 (2005), 326-335.
-
(2005)
Biochemical and Biophysical Research Communications
, vol.333
, pp. 326-335
-
-
Ferrara, N.1
Hillan, K.J.2
Novotny, W.3
-
21
-
-
0016256685
-
Tumor angiogenesis factor
-
J. Folkman, Tumor angiogenesis factor, Cancer Research, 34 (1974), 2109.
-
(1974)
Cancer Research
, vol.34
, pp. 2109
-
-
Folkman, J.1
-
22
-
-
0030500450
-
New perspectives in clinical oncology from angiogenesis research
-
J. Folkman, New perspectives in clinical oncology from angiogenesis research, European Journal of Cancer (Oxford, England: 1990), 32 (1996), 2534.
-
(1996)
European Journal of Cancer (Oxford, England: 1990)
, vol.32
, pp. 2534
-
-
Folkman, J.1
-
23
-
-
57149102486
-
Systems biology of vascular endothelial growth factors
-
F. M. Gabhann and A. S. Popel, Systems biology of vascular endothelial growth factors, Microcirculation, 15 (2008), 715-738.
-
(2008)
Microcirculation
, vol.15
, pp. 715-738
-
-
Gabhann, F.M.1
Popel, A.S.2
-
24
-
-
14544305077
-
Combination of antiangiogenic therapy with other anticancer therapies: Results, challenges, and open questions
-
G. Gasparini, R. Longo, M. Fanelli and B. A. Teicher, Combination of antiangiogenic therapy with other anticancer therapies: results, challenges, and open questions, Journal of Clinical Oncology, 23 (2005), 1295-1311.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. 1295-1311
-
-
Gasparini, G.1
Longo, R.2
Fanelli, M.3
Teicher, B.A.4
-
25
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway
-
H. P. Gerber, A. McMurtrey, J. Kowalski, M. Yan, B. A. Keyt, V. Dixit and N. Ferrara, Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway, Journal of Biological Chemistry, 273 (1998), 30336-30343.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
26
-
-
0000135489
-
Simulation of biological cell sorting using a two-dimensional extended Potts model
-
F. Graner and J. A. Glazier, Simulation of biological cell sorting using a two-dimensional extended Potts model, Physical Review Letters, 69 (1992), 2013-2016.
-
(1992)
Physical Review Letters
, vol.69
, pp. 2013-2016
-
-
Graner, F.1
Glazier, J.A.2
-
27
-
-
0041344538
-
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling
-
M. Hatakeyama, S. Kimura, T. Naka, T. Kawasaki, N. Yumoto, M. Ichikawa, J. H. Kim, K. Saito, M. Saeki, M. Shirouzu, S. Yokoyama and A. Konagaya, A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling, Biochemical Journal, 373 (2003), 451-463.
-
(2003)
Biochemical Journal
, vol.373
, pp. 451-463
-
-
Hatakeyama, M.1
Kimura, S.2
Naka, T.3
Kawasaki, T.4
Yumoto, N.5
Ichikawa, M.6
Kim, J.H.7
Saito, K.8
Saeki, M.9
Shirouzu, M.10
Yokoyama, S.11
Konagaya, A.12
-
28
-
-
38949102687
-
Analysis of mechanistic pathway models in drug discovery: P38 pathway
-
B. S. Hendriks, F. Hua and J. R. Chabot, Analysis of mechanistic pathway models in drug discovery: p38 pathway, Biotechnology Progress, 24 (2008), 96-109.
-
(2008)
Biotechnology Progress
, vol.24
, pp. 96-109
-
-
Hendriks, B.S.1
Hua, F.2
Chabot, J.R.3
-
30
-
-
7244231301
-
MAP kinases and cell migration
-
C. Huang, K. Jacobson and M. D. Schaller, MAP kinases and cell migration, Journal of Cell Science, 117 (2004), 4619-4628.
-
(2004)
Journal of Cell Science
, vol.117
, pp. 4619-4628
-
-
Huang, C.1
Jacobson, K.2
Schaller, M.D.3
-
31
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
R. K Jain, Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy, Nature Medicine, 7 (2001), 987-989.
-
(2001)
Nature Medicine
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
32
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
R. K Jain, Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy, Science, 307 (2005), 58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
33
-
-
0037079054
-
Computational systems biology
-
H. Kitano, Computational systems biology, Nature, 420 (2002), 206-210.
-
(2002)
Nature
, vol.420
, pp. 206-210
-
-
Kitano, H.1
-
34
-
-
0344010691
-
Cancer robustness: Tumour tactics
-
H. Kitano, Cancer robustness: tumour tactics, Nature, 426 (2003), 125-125.
-
(2003)
Nature
, vol.426
, pp. 125-125
-
-
Kitano, H.1
-
35
-
-
23444439817
-
Using process diagrams for the graphical representation of biological networks
-
H. Kitano, A. Funahashi, Y. Matsuoka and K. Oda, Using process diagrams for the graphical representation of biological networks, Nature Biotechnology, 23 (2005), 961-966.
-
(2005)
Nature Biotechnology
, vol.23
, pp. 961-966
-
-
Kitano, H.1
Funahashi, A.2
Matsuoka, Y.3
Oda, K.4
-
36
-
-
34250345272
-
Dynamics of tumor growth and combination of anti-angiogenic and cytotoxic therapies
-
M. Kohandel, M. Kardar, M. Milosevic and S. Sivaloganathan, Dynamics of tumor growth and combination of anti-angiogenic and cytotoxic therapies, Physics in Medicine and Biology, 52 (2007), 3665-3677.
-
(2007)
Physics in Medicine and Biology
, vol.52
, pp. 3665-3677
-
-
Kohandel, M.1
Kardar, M.2
Milosevic, M.3
Sivaloganathan, S.4
-
37
-
-
0033570090
-
Quantification of short term signaling by the epidermal growth factor receptor
-
B. N. Kholodenko, O. V. Demin, G. Moehren and J. B. Hoek, Quantification of short term signaling by the epidermal growth factor receptor, Journal of Biological Chemistry, 274 (1999), 30169-30181.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 30169-30181
-
-
Kholodenko, B.N.1
Demin, O.V.2
Moehren, G.3
Hoek, J.B.4
-
38
-
-
0034019315
-
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
-
B. N. Kholodenko, Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades, European Journal of Biochemistry, 267 (2001), 1583-1588.
-
(2001)
European Journal of Biochemistry
, vol.267
, pp. 1583-1588
-
-
Kholodenko, B.N.1
-
39
-
-
34147171490
-
Endothelial cell migration during angiogenesis
-
L. Lamalice, F. Le Boeuf and J. Huot, Endothelial cell migration during angiogenesis, Circulation Research, 100 (2007), 782-794.
-
(2007)
Circulation Research
, vol.100
, pp. 782-794
-
-
Lamalice, L.1
Le Boeuf, F.2
Huot, J.3
-
40
-
-
33144475089
-
Flow correlated percolation during vascular remodeling in growing tumors
-
D. S. Lee, H. Rieger and K. Bartha, Flow correlated percolation during vascular remodeling in growing tumors, Physical Review Letters, 96 (2006), 58104.
-
(2006)
Physical Review Letters
, vol.96
, pp. 58104
-
-
Lee, D.S.1
Rieger, H.2
Bartha, K.3
-
41
-
-
57749092182
-
Combination of antiangiogenesis with chemotherapy for more effective cancer treatment
-
J. Ma and D. J. Waxman, Combination of antiangiogenesis with chemotherapy for more effective cancer treatment, Molecular Cancer Therapeutics, 7 (2008), 3670-3684.
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, pp. 3670-3684
-
-
Ma, J.1
Waxman, D.J.2
-
42
-
-
16644400591
-
Mathematical modeling of tumor-induced angiogenesis
-
N. V. Mantzaris, S. Webb and H. G. Othmer, Mathematical modeling of tumor-induced angiogenesis, Journal of Mathematical Biology, 49 (2004), 111-187.
-
(2004)
Journal of Mathematical Biology
, vol.49
, pp. 111-187
-
-
Mantzaris, N.V.1
Webb, S.2
Othmer, H.G.3
-
43
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors
-
D. B. Mendel, A. D. Laird, X. Xin, S. G. Louie, J. G. Christensen, G. Li, R. E. Schreck, T. J. Abrams, T. J. Ngai, L. B. Lee and others, In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors, Clinical Cancer Research, 9 (2003), 327-337.
-
(2003)
Clinical Cancer Research
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
-
44
-
-
84862537741
-
Unraveling the inuence of endothelial cell density on VEGF-A signaling
-
L. Napione, S. Pavan, A. Veglio, A. Picco, G. Boffetta, A. Celani, G. Seano, L. Primo, A. Gamba and F. Bussolino, Unraveling the inuence of endothelial cell density on VEGF-A signaling, Blood (2012), 5599-5607.
-
(2012)
Blood
, pp. 5599-5607
-
-
Napione, L.1
Pavan, S.2
Veglio, A.3
Picco, A.4
Boffetta, G.5
Celani, A.6
Seano, G.7
Primo, L.8
Gamba, A.9
Bussolino, F.10
-
45
-
-
72749111836
-
Target-based therapies in breast cancer: Current status and future perspectives
-
N. Normanno, A. Morabito, A. De Luca, M. C. Piccirillo, M. Gallo, M. R. Maiello and F. Perrone, Target-based therapies in breast cancer: current status and future perspectives, Endocrine-related cancer, 16 (2009), 675-702.
-
(2009)
Endocrine-related Cancer
, vol.16
, pp. 675-702
-
-
Normanno, N.1
Morabito, A.2
De Luca, A.3
Piccirillo, M.C.4
Gallo, M.5
Maiello, M.R.6
Perrone, F.7
-
46
-
-
28644433993
-
Minimum information requested in the annotation of biochemical models (MIRIAM)
-
N. Le Novere, A. Finney, M. Hucka, U. S. Bhalla, F. Campagne, J. Collado-Vides, E. J. Crampin, M. Halstead, E. Klipp, P. Mendes and others, Minimum information requested in the annotation of biochemical models (MIRIAM), Nature Biotechnology, 23 (2005), 1509-1515.
-
(2005)
Nature Biotechnology
, vol.23
, pp. 1509-1515
-
-
Le Novere, N.1
Finney, A.2
Hucka, M.3
Bhalla, U.S.4
Campagne, F.5
Collado-Vides, J.6
Crampin, E.J.7
Halstead, M.8
Klipp, E.9
Mendes, P.10
-
47
-
-
33646107369
-
VEGF receptor signalling-in control of vascular function
-
A. K. Olsson, A. Dimberg, J. Kreuger and L. Claesson-Welsh, VEGF receptor signalling-in control of vascular function, Nat. Rev. Mol. Cell. Biol., 7 (2006), 357-371.
-
(2006)
Nat. Rev. Mol. Cell. Biol.
, vol.7
, pp. 357-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
48
-
-
3042661957
-
Role of cell cycle in mediating sensitivity to radiotherapy
-
T. M Pawlik and K. Keyomarsi, Role of cell cycle in mediating sensitivity to radiotherapy, International Journal of Radiation Oncology, Biology, Physics, 59 (2004), 928-942.
-
(2004)
International Journal of Radiation Oncology, Biology, Physics
, vol.59
, pp. 928-942
-
-
Pawlik, T.M.1
Keyomarsi, K.2
-
49
-
-
33748683966
-
Vascular endothelial growth factor receptors: Molecular mechanisms of activation and therapeutic potentials
-
N. Rahimi, Vascular endothelial growth factor receptors: molecular mechanisms of activation and therapeutic potentials, Experimental Eye Research, 83 (2006), 1005-1016.
-
(2006)
Experimental Eye Research
, vol.83
, pp. 1005-1016
-
-
Rahimi, N.1
-
50
-
-
33751226638
-
A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents
-
B. Ribba, O. Saut, T. Colin, D. Bresch, E. Grenier and J. P. Boissel, A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents, Journal of Theoretical Biology, 243 (2006), 532-541.
-
(2006)
Journal of Theoretical Biology
, vol.243
, pp. 532-541
-
-
Ribba, B.1
Saut, O.2
Colin, T.3
Bresch, D.4
Grenier, E.5
Boissel, J.P.6
-
51
-
-
66249093165
-
Chemotherapy may be delivered based on an integrated view of tumour dynamics
-
B. Ribba, B. You, M. Tod, P. Girard, B. Tranchand, V. Trillet-Lenoir and G. Freyer, Chemotherapy may be delivered based on an integrated view of tumour dynamics, IET Systems Biology, 3 (2009), 180-190.
-
(2009)
IET Systems Biology
, vol.3
, pp. 180-190
-
-
Ribba, B.1
You, B.2
Tod, M.3
Girard, P.4
Tranchand, B.5
Trillet-Lenoir, V.6
Freyer, G.7
-
52
-
-
33646249607
-
A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies
-
B. Ribba, T. Colin and S. Schnell, A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies, Theoretical Biology and Medical Modelling, 3 (2006).
-
(2006)
Theoretical Biology and Medical Modelling
, vol.3
-
-
Ribba, B.1
Colin, T.2
Schnell, S.3
-
53
-
-
33750715409
-
Mathematical modeling of cancer progression and response to chemotherapy
-
S. Sanga, J. P. Sinek, H. B. Frieboes, M. Ferrari, J. P. Fruehauf and V. Cristini, Mathematical modeling of cancer progression and response to chemotherapy, Expert review of anticancer therapy, 6 (2006), 1361-1376.
-
(2006)
Expert Review of Anticancer Therapy
, vol.6
, pp. 1361-1376
-
-
Sanga, S.1
Sinek, J.P.2
Frieboes, H.B.3
Ferrari, M.4
Fruehauf, J.P.5
Cristini, V.6
-
54
-
-
0036212767
-
Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
-
B. Schoeberl, C. Eichler-Jonsson, E. D. Gilles and G. Muller, Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors, Nature biotechnology, 20 (2002), 370-375.
-
(2002)
Nature Biotechnology
, vol.20
, pp. 370-375
-
-
Schoeberl, B.1
Eichler-Jonsson, C.2
Gilles, E.D.3
Muller, G.4
-
55
-
-
80051671525
-
A multiscale hybrid approach for vasculogenesis and related potential blocking therapies
-
M. Scianna, L. Munaron and L. Preziosi, A multiscale hybrid approach for vasculogenesis and related potential blocking therapies, Progress in Biophysics and Molecular Biology, 106 (2011), 450-462.
-
(2011)
Progress in Biophysics and Molecular Biology
, vol.106
, pp. 450-462
-
-
Scianna, M.1
Munaron, L.2
Preziosi, L.3
-
56
-
-
34247899028
-
Design of clinical trials of radiation combined with antiangiogenic therapy
-
S. Senan and E. F. Smit, Design of clinical trials of radiation combined with antiangiogenic therapy, The Oncologist, 12 (2007), 465-477.
-
(2007)
The Oncologist
, vol.12
, pp. 465-477
-
-
Senan, S.1
Smit, E.F.2
-
57
-
-
33750842076
-
Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
-
M. Shibuya, Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis., Journal of biochemistry and molecular biology, 39 (2006), 469-478.
-
(2006)
Journal of Biochemistry and Molecular Biology
, vol.39
, pp. 469-478
-
-
Shibuya, M.1
-
58
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
M. Shibuya and L. Claesson-Welsh, Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis, Experimental cell research, 312 (2006), 549-560.
-
(2006)
Experimental Cell Research
, vol.312
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
59
-
-
0842282616
-
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents
-
M. Simeoni, P. Magni, C. Cammia, G. De Nicolao, V. Croci, E. Pesenti, M. Germani, I. Poggesi and M. Rocchetti, Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents, Cancer Research, 64 (2004), 1094-1101.
-
(2004)
Cancer Research
, vol.64
, pp. 1094-1101
-
-
Simeoni, M.1
Magni, P.2
Cammia, C.3
De Nicolao, G.4
Croci, V.5
Pesenti, E.6
Germani, M.7
Poggesi, I.8
Rocchetti, M.9
-
60
-
-
25144511910
-
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
-
H. Takahashi and M. Shibuya, The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions, Clinical Science, 109 (2005), 227-241.
-
(2005)
Clinical Science
, vol.109
, pp. 227-241
-
-
Takahashi, H.1
Shibuya, M.2
-
61
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
R. T. Tong, Y. Boucher, S. V. Kozin, F. Winkler, D. J. Hicklin and R. K. Jain, Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors, Cancer research, 64 (2004), 3731-3736.
-
(2004)
Cancer Research
, vol.64
, pp. 3731-3736
-
-
Tong, R.T.1
Boucher, Y.2
Kozin, S.V.3
Winkler, F.4
Hicklin, D.J.5
Jain, R.K.6
-
62
-
-
0016836859
-
Proliferation-dependent cytotoxicity of anticancer agents: A review
-
F. Valeriote and L. van Putten, Proliferation-dependent cytotoxicity of anticancer agents: a review, Cancer Research, 35 (1975), 2619-2630.
-
(1975)
Cancer Research
, vol.35
, pp. 2619-2630
-
-
Valeriote, F.1
Van Putten, L.2
-
63
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
I. Vivanco and C. L. Sawyers, The phosphatidylinositol 3-Kinase AKT pathway in human cancer., Nature Reviews. Cancer, 2 (2002), 489-501.
-
(2002)
Nature Reviews. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
64
-
-
40149101292
-
Simulating non-small cell lung cancer with a multiscale agent-based model
-
Y. Wang, L. Zhang, J. Sagotsky and T. S. Deisboeck, Simulating non-small cell lung cancer with a multiscale agent-based model, Theoretical Biology and Medical Modelling, 4 (2007), 50.
-
(2007)
Theoretical Biology and Medical Modelling
, vol.4
, pp. 50
-
-
Wang, Y.1
Zhang, L.2
Sagotsky, J.3
Deisboeck, T.S.4
-
65
-
-
84866388429
-
Identification of critical molecular components in a multiscale cancer model based on the integration of Monte Carlo, resampling, and ANOVA
-
Z. Wang, V. Bordas and T. Deisboeck, Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA, Frontiers in Computational Physiology And Medicine, 2 (2011).
-
(2011)
Frontiers in Computational Physiology and Medicine
, vol.2
-
-
Wang, Z.1
Bordas, V.2
Deisboeck, T.3
-
66
-
-
37349011512
-
Emergent vascular network inhomogeneities and resulting blood ow patterns in a growing tumor
-
M. Welter, K. Bartha and H. Rieger, Emergent vascular network inhomogeneities and resulting blood ow patterns in a growing tumor, Journal of Theoretical Biology, 250 (2008), 257-280.
-
(2008)
Journal of Theoretical Biology
, vol.250
, pp. 257-280
-
-
Welter, M.1
Bartha, K.2
Rieger, H.3
-
67
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
C. G. Willett, Y. Boucher, F. Di Tomaso, D. G. Duda, L. L. Munn, R. T. Tong, D. C. Chung, D. V. Sahani, S. P. Kalva, S. V. Kozin, and others, Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer, Nature medicine, 10 (2004), 145-147.
-
(2004)
Nature Medicine
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
Di Tomaso, F.3
Duda, D.G.4
Munn, L.L.5
Tong, R.T.6
Chung, D.C.7
Sahani, D.V.8
Kalva, S.P.9
Kozin, S.V.10
-
68
-
-
19944422751
-
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
-
F. Winkler, S. V. Kozin, R. T. Tong, S. S. Chae, M. F. Booth, I. Garkavtsev, L. Xu, D. J. Hicklin, D. Fukumura, E. di Tomaso, L. L. Munn and R. K. Jain, Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation Role of oxygenation, angiopoietin-1, and matrix metalloproteinases, Cancer Cell, 6 (2004), 553-563.
-
(2004)
Cancer Cell
, vol.6
, pp. 553-563
-
-
Winkler, F.1
Kozin, S.V.2
Tong, R.T.3
Chae, S.S.4
Booth, M.F.5
Garkavtsev, I.6
Xu, L.7
Hicklin, D.J.8
Fukumura, D.9
Di Tomaso, E.10
Munn, L.L.11
Jain, R.K.12
-
69
-
-
13744255578
-
Nonlinear simulation of tumor necrosis, neovascularization and tissue invasion via an adaptive finite-element/level-set method
-
X. Zheng, S. M Wise and V. Cristini, Nonlinear simulation of tumor necrosis, neovascularization and tissue invasion via an adaptive finite-element/level-set method, Bulletin of mathematical biology, 67 (2005), 211-259.
-
(2005)
Bulletin of Mathematical Biology
, vol.67
, pp. 211-259
-
-
Zheng, X.1
Wise, S.M.2
Cristini, V.3
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