Modelling methodology in physiopathology

Progress in Biophysics and Molecular Biology

Volumn 97, Issue 1, 2008, Pages 28-39

  Boissel, Jean Pierre ^a,b,c   Ribba, Benjamin ^b   Grenier, Emmanuel ^b,d   Chapuisat, Guillemette ^b,e   Dronne, Marie Aimée ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ LYON 1   (France)

^c CENTRE LÉON BÉRARD   (France)

^d UNITÉ DE MATHÉMATIQUES PURES ET APPLIQUÉES   (France)

^e UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Methodology; Modelling; Strategy; Systems physiopathology

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENERAL ASPECTS OF DISEASE; HUMAN; METHODOLOGY; REVIEW; SYSTEMS BIOLOGY;

ANIMALS; COMPUTER SIMULATION; DISEASE; HUMANS; MODELS, BIOLOGICAL; SYSTEMS BIOLOGY;

EID: 43049177744     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2007.10.005     Document Type: Review

References (18)

1. Brenner S. Biological computation. In: Bock G., and Goode J.A. (Eds). The Limits of Reductionism in Biology. Proceedings of the Novartis Foundation Symposium (1998), Chichester, Wiley 106-116
2. Chapuisat, G., Dronne, M.A., Grenier, E., Hommel, M., Gilquin, H., Boissel, J.P., 2007. A global phenomenological model of ischemic stroke with stress on spreading depressions. Progress Biophys. Mol. Biol., in press, doi:10.1016/j.pbiomolbio.2007.10.004.
3. Descombes, S., Dumont, T., 2007. Numerical simulation of a stroke: computational problems and methodology. Progress Biophys. Mol. Biol., in press, doi:10.1016/j.pbiomolbio.2007.10.003.
4. Dronne M.A., Boissel J.P., and Grenier E. A mathematical model of ion movements in grey matter during a stroke. J. Theor. Biol. 240 (2006) 599-615
5. Dronne M.A., Boissel J.P., Grenier E., Gilquin H., Cucherat M., Hommel M., Barbier E., and Bricca G. Mathematical modelling of an ischemic stroke: an integrative approach. Acta Biotheor. 52 (2004) 255-272
6. Dronne, M.A., Grenier, E., Chapuisat, G., Hommel, M., Boissel, J.P., 2007a. A modelling approach to explore some hypotheses of the failure of neuroprotective trials in ischemic stroke patients. Progress Biophys. Mol. Biol., in press, doi:10.1016/j.pbiomolbio.2007.10.001.
7. Dronne M.A., Grenier E., Dumont T., Hommel M., and Boissel J.P. Role of astrocytes in grey matter during stroke: a modelling approach. Brain Res. 1138 (2007) 231-242
8. Gray D.S., Tien J., and Chen C.S. Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus. J. Biomed. Mater. Res. A 66 (2003) 605-614
9. Grenier, E., Descombes, S., Dronne, M.A., Jaillard, A., Hommel, M., Boissel, J.P., 2007. A numerical study of the blocking of migraine by Rolando sulcus. Progress Biophys. Mol. Biol., in press, doi:10.1016/j.pbiomolbio.2007.10.002.
10. Hodgkin A.L., and Huxley A.F. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117 (1952) 500-544
11. Huang H., Kamm R.D., and Lee R.T. Cell mechanics and mechanotransduction: pathways, probes, and physiology. Am. J. Physiol. Cell. Physiol. 287 (2004) C1-C11
12. Janmey P.A., and Weitz D.A. Dealing with mechanics: mechanisms of force transduction in cells. Trends Biochem. Sci. 29 (2004) 364-370
13. Noble, D., 2002. Final discussion. Is there a theoretical biology? In: Bock, G., Goode, J.A. (Eds.), "In silico" Simulation of Biological Processes. Proceedings of the Novartis Foundation Symposium. Wiley, Chichester, pp. 244-252.
14. Noble D. The future: putting Humpty-Dumpty together again. Biochem. Soc. Trans. 31 (2003) 156-158
15. Ribba B., Marron K., Agur Z., Alarcón T., and Maini P.K. A mathematical model of Doxorubicin treatment efficacy for non-Hodgkin's lymphoma: investigation of the current protocol through theoretical modelling results. Bull. Math. Biol. 67 (2005) 79-99
16. Ribba B., Colin T., and Schnell S. A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies. Theor. Biol. Med. Model. 10 (2006) 3-7
17. Ribba B., Saut O., Colin T., Bresch D., Grenier E., and Boissel J.P. A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents. J. Theor. Biol. 243 (2006) 532-541
18. Ribba B., Tracqui P., Boix J.-L., Boissel J.-P., and Thomas S.R. Generic database for modelling-QxDB: a generic database to support mathematical modeling in biology. Philos. Trans. A 364 (2006) 1517-1532