-
1
-
-
0025056721
-
Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6-sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides
-
Revankar GR, Hanna NB, Imamura N, Lewis AF, Larson SB, et al. (1990) Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6-sulfenamide,-sulfinamide, and-sulfonamide and related purine ribonucleosides. J Med Chem 33: 121-128.
-
(1990)
J Med Chem
, vol.33
, pp. 121-128
-
-
Revankar, G.R.1
Hanna, N.B.2
Imamura, N.3
Lewis, A.F.4
Larson, S.B.5
-
2
-
-
0025278171
-
Chemotherapeutic characterization in mice of 2-amino-9-beta-D-ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties
-
Avery TL, Finch RA, Vasquez KM, Radparvar S, Hanna NB, et al. (1990) Chemotherapeutic characterization in mice of 2-amino-9-beta-D-ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties. Cancer Res 50: 2625-2630.
-
(1990)
Cancer Res
, vol.50
, pp. 2625-2630
-
-
Avery, T.L.1
Finch, R.A.2
Vasquez, K.M.3
Radparvar, S.4
Hanna, N.B.5
-
3
-
-
33644647219
-
Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer
-
Bosch TM, Meijerman I, Beijnen JH, Schellens JH, (2006) Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. Clin Pharmacokinet 45: 253-285.
-
(2006)
Clin Pharmacokinet
, vol.45
, pp. 253-285
-
-
Bosch, T.M.1
Meijerman, I.2
Beijnen, J.H.3
Schellens, J.H.4
-
4
-
-
0036054299
-
Anti-angiogenic activity of the purine analog 6-thioguanine
-
Presta M, Belleri M, Vacca A, Ribatti D, (2002) Anti-angiogenic activity of the purine analog 6-thioguanine. Leukemia 16: 1490-1499.
-
(2002)
Leukemia
, vol.16
, pp. 1490-1499
-
-
Presta, M.1
Belleri, M.2
Vacca, A.3
Ribatti, D.4
-
5
-
-
66949148061
-
Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R)
-
Pesić M, Andjelković T, Banković J, Marković ID, Rakić L, et al. (2009) Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R). Invest New Drugs 27: 99-110.
-
(2009)
Invest New Drugs
, vol.27
, pp. 99-110
-
-
Pesić, M.1
Andjelković, T.2
Banković, J.3
Marković, I.D.4
Rakić, L.5
-
6
-
-
47949104284
-
S: Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)
-
Andjelkovic T, Pesic M, Bankovic J, Tanic N, Markovic ID, et al. (2008) S: Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R). Cancer Biol Ther 7: 1024-1032.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1024-1032
-
-
Andjelkovic, T.1
Pesic, M.2
Bankovic, J.3
Tanic, N.4
Markovic, I.D.5
-
7
-
-
77956632815
-
Purine analogs sensitize the multidrug resistant cell line (NCI-H460/R) to doxorubicin and stimulate the cell growth inhibitory effect of verapamil
-
Pesić M, Podolski A, Rakić L, Ruzdijić S, (2010) Purine analogs sensitize the multidrug resistant cell line (NCI-H460/R) to doxorubicin and stimulate the cell growth inhibitory effect of verapamil. Invest New Drugs 28: 482-492.
-
(2010)
Invest New Drugs
, vol.28
, pp. 482-492
-
-
Pesić, M.1
Podolski, A.2
Rakić, L.3
Ruzdijić, S.4
-
8
-
-
84867419830
-
Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression
-
doi:10.1002/med.20239
-
Nobili S, Landini I, Mazzei T, Mini E (2011) Overcoming tumor multidrug resistance using drugs able to evade P-glycoprotein or to exploit its expression. Med Res Rev, doi:10.1002/med.20239.
-
(2011)
Med Res Rev
-
-
Nobili, S.1
Landini, I.2
Mazzei, T.3
Mini, E.4
-
9
-
-
33645109974
-
Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs
-
Pesic M, Markovic JZ, Jankovic D, Kanazir S, Markovic ID, et al. (2006) Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs. J Chemother 18: 66-73.
-
(2006)
J Chemother
, vol.18
, pp. 66-73
-
-
Pesic, M.1
Markovic, J.Z.2
Jankovic, D.3
Kanazir, S.4
Markovic, I.D.5
-
10
-
-
79960967691
-
The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines
-
Podolski-Renić A, Andelković T, Banković J, Tanić N, Ruždijić S, et al. (2011) The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines. Biomed Pharmacother 65: 345-353.
-
(2011)
Biomed Pharmacother
, vol.65
, pp. 345-353
-
-
Podolski-Renić, A.1
Andelković, T.2
Banković, J.3
Tanić, N.4
Ruždijić, S.5
-
11
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, et al. (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
-
12
-
-
22344442480
-
Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer
-
Kang W, Nielsen O, Fenger C, Leslie G, Holmskov U, et al. (2005) Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. Carcinogenesis 26: 1129-1137.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1129-1137
-
-
Kang, W.1
Nielsen, O.2
Fenger, C.3
Leslie, G.4
Holmskov, U.5
-
13
-
-
0027711809
-
The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells
-
O'Driscoll L, Daly C, Saleh M, Clynes M, (1993) The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells. Cytotechnology 12: 289-314.
-
(1993)
Cytotechnology
, vol.12
, pp. 289-314
-
-
O'Driscoll, L.1
Daly, C.2
Saleh, M.3
Clynes, M.4
-
14
-
-
0033178714
-
Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
-
Harada H, Nakagawa K, Iwata S, Saito M, Kumon Y, et al. (1999) Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas. Cancer Res 59: 3783-3789.
-
(1999)
Cancer Res
, vol.59
, pp. 3783-3789
-
-
Harada, H.1
Nakagawa, K.2
Iwata, S.3
Saito, M.4
Kumon, Y.5
-
15
-
-
2642690680
-
Correlation between multidrug resistance and the degree of differentiation of non-small-cell bronchopulmonary carcinoma (NSCLC) in vitro and in vivo
-
Bosch S, Siavoshian S, Jacquot C, Tomasoni C, Dabouis G, et al. (1997) Correlation between multidrug resistance and the degree of differentiation of non-small-cell bronchopulmonary carcinoma (NSCLC) in vitro and in vivo. Anticancer Res 17: 4595-4598.
-
(1997)
Anticancer Res
, vol.17
, pp. 4595-4598
-
-
Bosch, S.1
Siavoshian, S.2
Jacquot, C.3
Tomasoni, C.4
Dabouis, G.5
-
16
-
-
61349121467
-
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis
-
Nardinocchi L, Puca R, Sacchi A, D'Orazi G, (2009) Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis. Mol Cancer 8: 1.
-
(2009)
Mol Cancer
, vol.8
, pp. 1
-
-
Nardinocchi, L.1
Puca, R.2
Sacchi, A.3
D'Orazi, G.4
-
17
-
-
0033046903
-
Altered expression of mRNAs for apoptosis-modulating proteins in a low level multidrug resistant variant of a human lung carcinoma cell line that also expresses mdr1 mRNA
-
NicAmhlaoibh R, Heenan M, Cleary I, Touhey S, O'Loughlin C, et al. (1999) Altered expression of mRNAs for apoptosis-modulating proteins in a low level multidrug resistant variant of a human lung carcinoma cell line that also expresses mdr1 mRNA. Int J Cancer 82: 368-376.
-
(1999)
Int J Cancer
, vol.82
, pp. 368-376
-
-
NicAmhlaoibh, R.1
Heenan, M.2
Cleary, I.3
Touhey, S.4
O'Loughlin, C.5
-
18
-
-
0028151418
-
Monitoring mRNA expression by polymerase chain reaction: the "primer-dropping" method
-
Wong H, Anderson WD, Cheng T, Riabowol KT, (1994) Monitoring mRNA expression by polymerase chain reaction: the "primer-dropping" method. Anal Biochem 223: 251-258.
-
(1994)
Anal Biochem
, vol.223
, pp. 251-258
-
-
Wong, H.1
Anderson, W.D.2
Cheng, T.3
Riabowol, K.T.4
-
19
-
-
79953683704
-
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma
-
Walbert T, Gilbert MR, Groves MD, Puduvalli VK, Yung WK, et al. (2011) Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma. J Neurooncol 102: 273-280.
-
(2011)
J Neurooncol
, vol.102
, pp. 273-280
-
-
Walbert, T.1
Gilbert, M.R.2
Groves, M.D.3
Puduvalli, V.K.4
Yung, W.K.5
-
21
-
-
44849106090
-
Induction of genetic instability by gain-of-function p53 cancer mutants
-
Xu Y, (2008) Induction of genetic instability by gain-of-function p53 cancer mutants. Oncogene 27: 3501-3507.
-
(2008)
Oncogene
, vol.27
, pp. 3501-3507
-
-
Xu, Y.1
-
22
-
-
47949088823
-
Cellular metabolism of the antitumor nucleoside, sulfinosine, 2-amino-9-(β-D-ribofuranosyl) purine-6-sulfinamide
-
Fujitaki JM, Nord LD, Willis RC, (1989) Cellular metabolism of the antitumor nucleoside, sulfinosine, 2-amino-9-(β-D-ribofuranosyl) purine-6-sulfinamide. Proc Am Assoc Cancer Res 30: 596.
-
(1989)
Proc Am Assoc Cancer Res
, vol.30
, pp. 596
-
-
Fujitaki, J.M.1
Nord, L.D.2
Willis, R.C.3
-
23
-
-
47949107157
-
Isolation, identification, synthesis and therapeutic evaluation of selected metabolites of sulfinosine a novel purine nucleoside analog active against thiopurine refractory experimental leukemia
-
Riley TA, Finch RA, Vasquez KM, (1989) Isolation, identification, synthesis and therapeutic evaluation of selected metabolites of sulfinosine a novel purine nucleoside analog active against thiopurine refractory experimental leukemia. Proc Am Assoc Cancer Res 30: 599.
-
(1989)
Proc Am Assoc Cancer Res
, vol.30
, pp. 599
-
-
Riley, T.A.1
Finch, R.A.2
Vasquez, K.M.3
-
24
-
-
0037439691
-
Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance
-
Rudin CM, Yang Z, Schumaker LM, VanderWeele DJ, Newkirk K, et al. (2003) Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance. Cancer Res 63: 312-318.
-
(2003)
Cancer Res
, vol.63
, pp. 312-318
-
-
Rudin, C.M.1
Yang, Z.2
Schumaker, L.M.3
VanderWeele, D.J.4
Newkirk, K.5
-
25
-
-
0032723945
-
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis
-
Ghibelli L, Coppola S, Fanelli C, Rotilio G, Civitareale P, et al. (1999) Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis. FASEB J 13: 2031-2036.
-
(1999)
FASEB J
, vol.13
, pp. 2031-2036
-
-
Ghibelli, L.1
Coppola, S.2
Fanelli, C.3
Rotilio, G.4
Civitareale, P.5
-
26
-
-
82955212778
-
Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation
-
doi:10.1007/s11060-011-0632-3
-
Chang CY, Shen CC, Su HL, Chen CJ (2011) Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation. J Neurooncol. doi:10.1007/s11060-011-0632-3.
-
(2011)
J Neurooncol
-
-
Chang, C.Y.1
Shen, C.C.2
Su, H.L.3
Chen, C.J.4
-
27
-
-
79958002572
-
HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation
-
Li G, Xu Y, Guan D, Liu Z, Liu DX, (2011) HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation. J Biol Chem 286: 20251-20259.
-
(2011)
J Biol Chem
, vol.286
, pp. 20251-20259
-
-
Li, G.1
Xu, Y.2
Guan, D.3
Liu, Z.4
Liu, D.X.5
-
28
-
-
77955432889
-
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma
-
Voss V, Senft C, Lang V, Ronellenfitsch MW, Steinbach JP, et al. (2010) The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res 8: 1002-1016.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1002-1016
-
-
Voss, V.1
Senft, C.2
Lang, V.3
Ronellenfitsch, M.W.4
Steinbach, J.P.5
-
29
-
-
79958826703
-
Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death
-
Eimer S, Belaud-Rotureau MA, Airiau K, Jeanneteau M, Laharanne E, et al. (2011) Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death. Cancer Biol Ther 11: 1017-1027.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 1017-1027
-
-
Eimer, S.1
Belaud-Rotureau, M.A.2
Airiau, K.3
Jeanneteau, M.4
Laharanne, E.5
-
30
-
-
34548188741
-
Self-eating and self-killing: crosstalk between autophagy and apoptosis
-
Maiuri MC, Zalckvar E, Kimchi A, Kroemer G, (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
31
-
-
33847185842
-
A redox cycle within the cell cycle: ring in the old with the new
-
Menon SG, Goswami PC, (2007) A redox cycle within the cell cycle: ring in the old with the new. Oncogene 26: 1101-1109.
-
(2007)
Oncogene
, vol.26
, pp. 1101-1109
-
-
Menon, S.G.1
Goswami, P.C.2
-
32
-
-
0038368985
-
Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide
-
Zhao H, Kalivendi S, Zhang H, Joseph J, Nithipatikom K, et al. (2003) Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. Free Radic Biol Med 34: 1359-1368.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1359-1368
-
-
Zhao, H.1
Kalivendi, S.2
Zhang, H.3
Joseph, J.4
Nithipatikom, K.5
-
33
-
-
0037733975
-
The importance of glutathione in human disease. Biomed
-
Townsend DM, Tew KD, Tapiero H, (2003) The importance of glutathione in human disease. Biomed. Pharmacother 57: 145-155.
-
(2003)
Pharmacother
, vol.57
, pp. 145-155
-
-
Townsend, D.M.1
Tew, K.D.2
Tapiero, H.3
-
34
-
-
0023475509
-
Inhibition of the synthesis of glycoproteins and induction of the differentiation of HL-60 promyelocytic leukemia cells by 6-methylmercaptopurine ribonucleoside
-
Sokoloski JA, Sartorelli AC, (1987) Inhibition of the synthesis of glycoproteins and induction of the differentiation of HL-60 promyelocytic leukemia cells by 6-methylmercaptopurine ribonucleoside. Cancer Res 47: 6283-6287.
-
(1987)
Cancer Res
, vol.47
, pp. 6283-6287
-
-
Sokoloski, J.A.1
Sartorelli, A.C.2
-
35
-
-
0030969559
-
Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma
-
Fontanini G, Vignati S, Boldrini L, Chinè S, Silvestri V, et al. (1997) Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma. Clin Cancer Res 3: 861-865.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 861-865
-
-
Fontanini, G.1
Vignati, S.2
Boldrini, L.3
Chinè, S.4
Silvestri, V.5
-
36
-
-
3042556117
-
Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas
-
Jansen M, de Witt Hamer PC, Witmer AN, Troost D, van Noorden CJ, (2004) Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas. Brain Res Rev 45: 143-163.
-
(2004)
Brain Res Rev
, vol.45
, pp. 143-163
-
-
Jansen, M.1
de Witt Hamer, P.C.2
Witmer, A.N.3
Troost, D.4
van Noorden, C.J.5
-
37
-
-
67449107060
-
Emerging data with antiangiogenic therapies in early and advanced non-small-cell lung cancer
-
Horn L, Sandler AB, (2009) Emerging data with antiangiogenic therapies in early and advanced non-small-cell lung cancer. Clin Lung Cancer 10: S7-16.
-
(2009)
Clin Lung Cancer
, vol.10
, pp. 7-16
-
-
Horn, L.1
Sandler, A.B.2
-
38
-
-
1642295074
-
Development of vascular endothelial growth factor receptor (VEGFR) kinase inhibitors as anti-angiogenic agents in cancer therapy
-
Underiner TL, Ruggeri B, Gingrich DE, (2004) Development of vascular endothelial growth factor receptor (VEGFR) kinase inhibitors as anti-angiogenic agents in cancer therapy. Curr Med Chem 11: 731-745.
-
(2004)
Curr Med Chem
, vol.11
, pp. 731-745
-
-
Underiner, T.L.1
Ruggeri, B.2
Gingrich, D.E.3
-
39
-
-
79955987607
-
Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells
-
Jin WS, Kong ZL, Shen ZF, Jin YZ, Zhang WK, et al. (2011) Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells. J Exp Clin Cancer Res 30: 61.
-
(2011)
J Exp Clin Cancer Res
, vol.30
, pp. 61
-
-
Jin, W.S.1
Kong, Z.L.2
Shen, Z.F.3
Jin, Y.Z.4
Zhang, W.K.5
-
40
-
-
84856072503
-
Modulation of P-gp expression by lapatinib
-
Dunne G, Breen L, Collins DM, Roche S, Clynes M, et al. (2011) Modulation of P-gp expression by lapatinib. Invest New Drugs 29: 1284-1293.
-
(2011)
Invest New Drugs
, vol.29
, pp. 1284-1293
-
-
Dunne, G.1
Breen, L.2
Collins, D.M.3
Roche, S.4
Clynes, M.5
-
41
-
-
75349108100
-
Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor
-
Hawkins BT, Sykes DB, Miller DS, (2010) Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor. J Neurosci 30: 1417-1425.
-
(2010)
J Neurosci
, vol.30
, pp. 1417-1425
-
-
Hawkins, B.T.1
Sykes, D.B.2
Miller, D.S.3
-
42
-
-
0242456119
-
Treatment of non-small-cell lung cancer: state of the art and development of new biologic agents
-
Gridelli C, Rossi A, Maione P, (2003) Treatment of non-small-cell lung cancer: state of the art and development of new biologic agents. Oncogene 22: 6629-6638.
-
(2003)
Oncogene
, vol.22
, pp. 6629-6638
-
-
Gridelli, C.1
Rossi, A.2
Maione, P.3
-
43
-
-
34447313404
-
The role of membrane transporters in drug delivery to brain tumors
-
Nies AT, (2007) The role of membrane transporters in drug delivery to brain tumors. Cancer Lett 254: 11-29.
-
(2007)
Cancer Lett
, vol.254
, pp. 11-29
-
-
Nies, A.T.1
-
44
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system
-
Sarkadi B, Homolya L, Szakács G, Váradi A, (2006) Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev 86: 1179-1236.
-
(2006)
Physiol Rev
, vol.86
, pp. 1179-1236
-
-
Sarkadi, B.1
Homolya, L.2
Szakács, G.3
Váradi, A.4
|