-
1
-
-
0025675811
-
Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells
-
Zambruno, G.; Girolomoni, G.; Manca, V.; Segre, A.; Giannetti, A. Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells. Arch. Dermatol. Res. 1990, 282, 544-548.
-
(1990)
Arch. Dermatol. Res.
, vol.282
, pp. 544-548
-
-
Zambruno, G.1
Girolomoni, G.2
Manca, V.3
Segre, A.4
Giannetti, A.5
-
2
-
-
46749122327
-
Beyond wavy hairs: The epidermal growth factor receptor and its ligands in skin biology and pathology
-
Schneider, M.R.; Werner, S.; Paus, R.; Wolf, E. Beyond wavy hairs: The epidermal growth factor receptor and its ligands in skin biology and pathology. Am. J. Pathol. 2008, 173, 14-24.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 14-24
-
-
Schneider, M.R.1
Werner, S.2
Paus, R.3
Wolf, E.4
-
3
-
-
73149098115
-
Growth factors and corneal epithelial wound healing
-
Yu, F.S.; Yin, J.; Xu, K.; Huang, J. Growth factors and corneal epithelial wound healing. Brain Res. Bull. 2010, 81, 229-235.
-
(2010)
Brain Res. Bull.
, vol.81
, pp. 229-235
-
-
Yu, F.S.1
Yin, J.2
Xu, K.3
Huang, J.4
-
4
-
-
0029064203
-
Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
-
Threadgill, D.W.; Dlugosz, A.A.; Hansen, L.A.; Tennenbaum, T.; Lichti, U.; Yee, D.; LaMantia, C.; Mourton, T.; Herrup, K.; Harris, R.C.; et al. Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype. Science 1995, 269, 230-234.
-
(1995)
Science
, vol.269
, pp. 230-234
-
-
Threadgill, D.W.1
Dlugosz, A.A.2
Hansen, L.A.3
Tennenbaum, T.4
Lichti, U.5
Yee, D.6
La Mantia, C.7
Mourton, T.8
Herrup, K.9
Harris, R.C.10
-
5
-
-
0032795261
-
Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
-
Luetteke, N.C.; Qiu, T.H.; Fenton, S.E.; Troyer, K.L.; Riedel, R.F.; Chang, A.; Lee, D.C. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development 1999, 126, 2739-2750.
-
(1999)
Development
, vol.126
, pp. 2739-2750
-
-
Luetteke, N.C.1
Qiu, T.H.2
Fenton, S.E.3
Troyer, K.L.4
Riedel, R.F.5
Chang, A.6
Lee, D.C.7
-
6
-
-
1542329005
-
The erbB Family: Targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors
-
Rowinsky, E.K. The erbB Family: Targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors. Ann. Rev. Med. 2004, 55, 433-457.
-
(2004)
Ann. Rev. Med.
, vol.55
, pp. 433-457
-
-
Rowinsky, E.K.1
-
7
-
-
34547114456
-
Pathways of clathrin-independent endocytosis
-
Mayor, S.; Pagano, R.E. Pathways of clathrin-independent endocytosis. Nat. Rev. Mol. Cell Biol. 2007, 8, 603-612.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 603-612
-
-
Mayor, S.1
Pagano, R.E.2
-
8
-
-
14544306526
-
Clathrin-independent endocytosis of ubiquinated cargos
-
Sigismund, S.; Woelk, T.; Puri, C.; Maspero, E.; Tacchetti, C.; Transidico, P.; Di Fiore, P.P.; Polo, S. Clathrin-independent endocytosis of ubiquinated cargos. Proc. Natl. Acad. Sci. USA 2005, 102, 2760-2765.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2760-2765
-
-
Sigismund, S.1
Woelk, T.2
Puri, C.3
Maspero, E.4
Tacchetti, C.5
Transidico, P.6
Di Fiore, P.P.7
Polo, S.8
-
9
-
-
0028224965
-
Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions
-
French, A.R.; Sudlow, G.P.; Wiley, H.S.; Lauffenburger, D.A. Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions. J. Biol. Chem. 1994, 269, 15749-15755.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15749-15755
-
-
French, A.R.1
Sudlow, G.P.2
Wiley, H.S.3
Lauffenburger, D.A.4
-
10
-
-
0021219986
-
Characterization of the metabolic turnover of epidermal growth factor receptor protein in A431 cells
-
Stoscheck, C.M.; Carpenter, G. Characterization of the metabolic turnover of epidermal growth factor receptor protein in A431 cells. J. Cell Phys. 1984, 120, 296-302.
-
(1984)
J. Cell Phys.
, vol.120
, pp. 296-302
-
-
Stoscheck, C.M.1
Carpenter, G.2
-
11
-
-
79960720320
-
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
-
McMahon, H.T.; Boucrot, E. Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat. Rev. Mol. Cell Biol. 2011, 12, 517-533.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 517-533
-
-
McMahon, H.T.1
Boucrot, E.2
-
12
-
-
0017103026
-
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts
-
Carpenter, G.; Cohen, S. 125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts. J. Cell Biol. 1976, 71, 159-171.
-
(1976)
J. Cell Biol.
, vol.71
, pp. 159-171
-
-
Carpenter, G.1
Cohen, S.2
-
13
-
-
0026574126
-
Kinetics of binding, endocytosis, and recycling of EGF receptor mutants
-
Felder, S.; La Vin, J.; Ullrich, A.; Schlessinger, J. Kinetics of binding, endocytosis, and recycling of EGF receptor mutants. J. Cell Biol. 1992, 117, 203-212.
-
(1992)
J. Cell Biol.
, vol.117
, pp. 203-212
-
-
Felder, S.1
La Vin, J.2
Ullrich, A.3
Schlessinger, J.4
-
14
-
-
73649140612
-
Epidermal growth factor receptor translocation to the mitochondria: Regulation and effect
-
Demory, M.L.; Boerner, J.L.; Davidson, R.; Faust, W.; Miyake, T.; Lee, I.; Huttemann, M.; Douglas, R.; Haddad, G.; Parsons, S.J. Epidermal growth factor receptor translocation to the mitochondria: Regulation and effect. J. Biol. Chem. 2009, 284, 36592-36604.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 36592-36604
-
-
Demory, M.L.1
Boerner, J.L.2
Davidson, R.3
Faust, W.4
Miyake, T.5
Lee, I.6
Huttemann, M.7
Douglas, R.8
Haddad, G.9
Parsons, S.J.10
-
15
-
-
77951746203
-
Rab7b controls trafficking from endosomes to the TGN
-
Progida, C.; Cogli, L.; Piro, F.; De Luca, A.; Bakke, O.; Bucci, C. Rab7b controls trafficking from endosomes to the TGN. J. Cell Sci. 2010, 123, 1480-1491.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1480-1491
-
-
Progida, C.1
Cogli, L.2
Piro, F.3
de Luca, A.4
Bakke, O.5
Bucci, C.6
-
16
-
-
0036500994
-
Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum
-
Haj, F.G.; Verveer, P.J.; Squire, A.; Neel, B.G.; Bastiaens, P.I. Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Science 2002, 295, 1708-1711.
-
(2002)
Science
, vol.295
, pp. 1708-1711
-
-
Haj, F.G.1
Verveer, P.J.2
Squire, A.3
Neel, B.G.4
Bastiaens, P.I.5
-
17
-
-
33947118714
-
Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression
-
Liao, H.J.; Carpenter, G. Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression. Mol. Biol. Cell. 2007, 18, 1064-1072.
-
(2007)
Mol. Biol. Cell.
, vol.18
, pp. 1064-1072
-
-
Liao, H.J.1
Carpenter, G.2
-
18
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
Lin, S.Y.; Makino, K.; Xia, W.; Matin, A.; Wen, Y.; Kwong, K.Y.; Bourguignon, L.; Hung, M.C. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell Biol. 2001, 3, 802-808.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
Makino, K.2
Xia, W.3
Matin, A.4
Wen, Y.5
Kwong, K.Y.6
Bourguignon, L.7
Hung, M.C.8
-
19
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira, A.V.; Lamaze, C.; Schmid, S.L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 1996, 274, 2086-2089.
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
20
-
-
0035162703
-
Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
-
Burke, P.; Schooler, K.; Wiley, H.S. Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking. Mol. Biol. Cell. 2001, 12, 1897-1910.
-
(2001)
Mol. Biol. Cell.
, vol.12
, pp. 1897-1910
-
-
Burke, P.1
Schooler, K.2
Wiley, H.S.3
-
21
-
-
33746160962
-
Regulation of EGFR endocytic trafficking by rab proteins
-
Ceresa, B.P. Regulation of EGFR endocytic trafficking by rab proteins. Histol. Histopathol. 2006, 21, 987-993.
-
(2006)
Histol. Histopathol.
, vol.21
, pp. 987-993
-
-
Ceresa, B.P.1
-
22
-
-
84870204151
-
The Rab family of proteins: 25 years on
-
Kelly, E.E.; Horgan, C.P.; Goud, B.; McCaffrey, M.W. The Rab family of proteins: 25 years on. Biochem. Soc. Trans. 2012, 40, 1337-1347.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 1337-1347
-
-
Kelly, E.E.1
Horgan, C.P.2
Goud, B.3
McCaffrey, M.W.4
-
23
-
-
84856111189
-
Dynamin, a membrane-remodelling GTPase
-
Ferguson, S.M.; De Camilli, P. Dynamin, a membrane-remodelling GTPase. Nat. Rev. Mol. Cell Biol. 2012, 13, 75-88.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 75-88
-
-
Ferguson, S.M.1
de Camilli, P.2
-
24
-
-
0032217156
-
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
Levkowitz, G.; Waterman, H.; Zamir, E.; Kam, Z.; Oved, S.; Langdon, W.Y.; Beguinot, L.; Geiger, B.; Yarden, Y. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev. 1998, 12, 3663-3674.
-
(1998)
Genes Dev.
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
Waterman, H.2
Zamir, E.3
Kam, Z.4
Oved, S.5
Langdon, W.Y.6
Beguinot, L.7
Geiger, B.8
Yarden, Y.9
-
25
-
-
0036469898
-
A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
-
Waterman, H.; Katz, M.; Rubin, C.; Shtiegman, K.; Lavi, S.; Elson, A.; Jovin, T.M.; Yarden, Y. A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling. EMBO J. 2002, 21, 303-313.
-
(2002)
EMBO J.
, vol.21
, pp. 303-313
-
-
Waterman, H.1
Katz, M.2
Rubin, C.3
Shtiegman, K.4
Lavi, S.5
Elson, A.6
Jovin, T.M.7
Yarden, Y.8
-
26
-
-
4744342856
-
Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation
-
Grovdal, L.M.; Stang, E.; Sorkin, A.; Madshus, I.H. Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation. Exp. Cell Res. 2004, 300, 388-395.
-
(2004)
Exp. Cell Res.
, vol.300
, pp. 388-395
-
-
Grovdal, L.M.1
Stang, E.2
Sorkin, A.3
Madshus, I.H.4
-
27
-
-
0348014544
-
Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor
-
Oksvold, M.P.; Thien, C.B.; Widerberg, J.; Chantry, A.; Huitfeldt, H.S.; Langdon, W.Y. Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor. Oncogene 2003, 22, 8509-8518.
-
(2003)
Oncogene
, vol.22
, pp. 8509-8518
-
-
Oksvold, M.P.1
Thien, C.B.2
Widerberg, J.3
Chantry, A.4
Huitfeldt, H.S.5
Langdon, W.Y.6
-
28
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
Fallon, L.; Belanger, C.M.; Corera, A.T.; Kontogiannea, M.; Regan-Klapisz, E.; Moreau, F.; Voortman, J.; Haber, M.; Rouleau, G.; Thorarinsdottir, T.; et al. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat. Cell Biol. 2006, 8, 834-842.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
-
29
-
-
3342970389
-
Cbl-dependent ubituination is required for progression of EGF receptors into clathrin-coated pits
-
Stang, E.; Blystad, F.D.; Kazazic, M.; Bertelsen, V.; Brodahl, T.; Raiborg, C.; Stenmark, H.; Madshus, I.H. Cbl-dependent ubituination is required for progression of EGF receptors into clathrin-coated pits. Mol. Biol. Cell. 2006, 15, 3591-3604.
-
(2006)
Mol. Biol. Cell.
, vol.15
, pp. 3591-3604
-
-
Stang, E.1
Blystad, F.D.2
Kazazic, M.3
Bertelsen, V.4
Brodahl, T.5
Raiborg, C.6
Stenmark, H.7
Madshus, I.H.8
-
30
-
-
84855979997
-
The role of EGF receptor ubiquitination in regulating its intracellular traffic
-
Eden, E.R.; Huang, F.; Sorkin, A.; Futter, C.E. The role of EGF receptor ubiquitination in regulating its intracellular traffic. Traffic 2012, 13, 329-337.
-
(2012)
Traffic
, vol.13
, pp. 329-337
-
-
Eden, E.R.1
Huang, F.2
Sorkin, A.3
Futter, C.E.4
-
31
-
-
0037018146
-
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies
-
Longva, K.E.; Blystad, F.D.; Stang, E.; Larsen, A.M.; Johannessen, L.E.; Madshus, I.H. Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J. Cell Biol. 2002, 156, 843-854.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 843-854
-
-
Longva, K.E.1
Blystad, F.D.2
Stang, E.3
Larsen, A.M.4
Johannessen, L.E.5
Madshus, I.H.6
-
32
-
-
0038394715
-
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
-
Haglund, K.; Sigismund, S.; Polo, S.; Szymkiewicz, I.; Di Fiore, P.P.; Dikic, I. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat. Cell Biol. 2003, 5, 461-466.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 461-466
-
-
Haglund, K.1
Sigismund, S.2
Polo, S.3
Szymkiewicz, I.4
Di Fiore, P.P.5
Dikic, I.6
-
33
-
-
36749036679
-
EGF receptor ubiquitination is not necessary for its internalization
-
Huang, F.; Goh, L.K.; Sorkin, A. EGF receptor ubiquitination is not necessary for its internalization. Proc. Natl. Acad. Sci. USA 2007, 104, 16904-16909.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16904-16909
-
-
Huang, F.1
Goh, L.K.2
Sorkin, A.3
-
34
-
-
79952785850
-
A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner
-
Bertelsen, V.; Sak, M.M.; Breen, K.; Rodland, M.S.; Johannessen, L.E.; Traub, L.M.; Stang, E.; Madshus, I.H. A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner. Traffic 2011, 12, 507-520.
-
(2011)
Traffic
, vol.12
, pp. 507-520
-
-
Bertelsen, V.1
Sak, M.M.2
Breen, K.3
Rodland, M.S.4
Johannessen, L.E.5
Traub, L.M.6
Stang, E.7
Madshus, I.H.8
-
35
-
-
54549102284
-
Derailed endocytosis: An emerging feature of cancer
-
Mosesson, Y.; Mills, G.B.; Yarden, Y. Derailed endocytosis: An emerging feature of cancer. Nat. Rev. Cancer 2008, 8, 835-850.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 835-850
-
-
Mosesson, Y.1
Mills, G.B.2
Yarden, Y.3
-
36
-
-
71949085528
-
Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src
-
Chung, B.M.; Raja, S.M.; Clubb, R.J.; Tu, C.; George, M.; Band, V.; Band, H. Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src. BMC Cell Biol. 2009, 10, 84.
-
(2009)
BMC Cell Biol.
, vol.10
, pp. 84
-
-
Chung, B.M.1
Raja, S.M.2
Clubb, R.J.3
Tu, C.4
George, M.5
Band, V.6
Band, H.7
-
37
-
-
77955905060
-
Transforming growth factor-α (TGF-α) enhances corneal epithelial cell migration by promoting EGFR recycling
-
McClintock, J.L.; Ceresa, B.P. Transforming growth factor-α (TGF-α) enhances corneal epithelial cell migration by promoting EGFR recycling. Invest. Opththalmol. Vis. Sci. 2010, 51, 3455-3461.
-
(2010)
Invest. Opththalmol. Vis. Sci.
, vol.51
, pp. 3455-3461
-
-
McClintock, J.L.1
Ceresa, B.P.2
-
38
-
-
78651105303
-
Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration
-
Assaker, G.; Ramel, D.; Wculek, S.K.; Gonzalez-Gaitan, M.; Emery, G. Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. Proc. Natl. Acad. Sci. USA 2010, 107, 22558-22563.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22558-22563
-
-
Assaker, G.1
Ramel, D.2
Wculek, S.K.3
Gonzalez-Gaitan, M.4
Emery, G.5
-
39
-
-
84860493602
-
RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans
-
Skorobogata, O.; Rocheleau, C.E. RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans. PLoS One 2012, 7, e36489.
-
(2012)
PLoS One
, vol.7
-
-
Skorobogata, O.1
Rocheleau, C.E.2
-
40
-
-
0028916337
-
Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain
-
Opresko, L.K.; Chang, C.P.; Will, B.H.; Burke, P.M.; Gill, G.N.; Wiley, H.S. Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain. J. Biol. Chem. 1995, 270, 4325-4333.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4325-4333
-
-
Opresko, L.K.1
Chang, C.P.2
Will, B.H.3
Burke, P.M.4
Gill, G.N.5
Wiley, H.S.6
-
41
-
-
0025139326
-
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
-
Wells, A.; Welsh, J.B.; Lazar, C.S.; Wiley, H.S.; Gill, G.N.; Rosenfeld, M.G. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science 1990, 247, 962-964.
-
(1990)
Science
, vol.247
, pp. 962-964
-
-
Wells, A.1
Welsh, J.B.2
Lazar, C.S.3
Wiley, H.S.4
Gill, G.N.5
Rosenfeld, M.G.6
-
42
-
-
0242444471
-
Visualization of acidic organelles in intact cells by electron microscopy
-
Anderson, R.G.; Falck, J.R.; Goldstein, J.L.; Brown, M.S. Visualization of acidic organelles in intact cells by electron microscopy. Proc. Natl. Acad. Sci. USA 1984, 81, 4838-4842.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 4838-4842
-
-
Anderson, R.G.1
Falck, J.R.2
Goldstein, J.L.3
Brown, M.S.4
-
43
-
-
0021702553
-
Monensin, like methylamine, prevents degradation of 125I-epidermal growth factor, causes intracellular accumulation of receptors and blocks the mitogenic response
-
King, A.C. Monensin, like methylamine, prevents degradation of 125I-epidermal growth factor, causes intracellular accumulation of receptors and blocks the mitogenic response. Biochem. Biophys. Res. Commun. 1984, 124, 585-591.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.124
, pp. 585-591
-
-
King, A.C.1
-
44
-
-
0030610528
-
Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling
-
Presly, J.F.; Mayor, S.; McGraw, T.E.; Dunn, K.W.; Maxfield, F.R. Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. J. Biol. Chem. 1997, 272, 13929-13936.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13929-13936
-
-
Presly, J.F.1
Mayor, S.2
McGraw, T.E.3
Dunn, K.W.4
Maxfield, F.R.5
-
45
-
-
4744360232
-
Role of rab5 in EGF receptor-mediated signal transduction
-
Barbieri, M.A.; Fernandez-Pol, S.; Hunker, C.; Horazodovsky, B.F.; Stahl, P.D. Role of rab5 in EGF receptor-mediated signal transduction. Eur. J. Cell Biol. 2004, 83, 305-314.
-
(2004)
Eur. J. Cell Biol.
, vol.83
, pp. 305-314
-
-
Barbieri, M.A.1
Fernandez-Pol, S.2
Hunker, C.3
Horazodovsky, B.F.4
Stahl, P.D.5
-
46
-
-
0028036513
-
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
-
Damke, H.; Baba, T.; Warnock, D.E.; Schmid, S.L. Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J. Cell Biol. 1994, 127, 915-934.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 915-934
-
-
Damke, H.1
Baba, T.2
Warnock, D.E.3
Schmid, S.L.4
-
47
-
-
1542328950
-
Expression of dominant negative rab5 in HeLa cells regulates EGFR endocytic trafficking distal from the plasma membrane
-
Dinneen, J.L.; Ceresa, B.P. Expression of dominant negative rab5 in HeLa cells regulates EGFR endocytic trafficking distal from the plasma membrane. Exp. Cell Res. 2004, 294, 509-522.
-
(2004)
Exp. Cell Res.
, vol.294
, pp. 509-522
-
-
Dinneen, J.L.1
Ceresa, B.P.2
-
48
-
-
71049118063
-
Rab5 isoforms differentially regulate the trafficking and degradation of epidermal growth factor receptors
-
Chen, P.I.; Kong, C.; Su, X.; Stahl, P.D. Rab5 isoforms differentially regulate the trafficking and degradation of epidermal growth factor receptors. J. Biol. Chem. 2009, 284, 30328-30338.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30328-30338
-
-
Chen, P.I.1
Kong, C.2
Su, X.3
Stahl, P.D.4
-
49
-
-
0020601856
-
Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells
-
Hopkins, C.R.; Trowbridge, I.S. Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells. J. Cell Biol. 1983, 97, 508-521.
-
(1983)
J. Cell Biol.
, vol.97
, pp. 508-521
-
-
Hopkins, C.R.1
Trowbridge, I.S.2
-
50
-
-
67649889124
-
Differential effects of EGFR ligands on endocytic sorting of the receptor
-
Roepstorff, K.; Grandal, M.V.; Henriksen, L.; Knudsen, S.L.; Lerdrup, M.; Grovdal, L.; Willumsen, B.M.; van Deurs, B. Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic 2009, 10, 1115-1127.
-
(2009)
Traffic
, vol.10
, pp. 1115-1127
-
-
Roepstorff, K.1
Grandal, M.V.2
Henriksen, L.3
Knudsen, S.L.4
Lerdrup, M.5
Grovdal, L.6
Willumsen, B.M.7
van Deurs, B.8
-
51
-
-
0041885279
-
Local signaling by the EGF receptor
-
Kempiak, S.J.; Yip, S.-C.; Backer, J.M.; Segall, J.E. Local signaling by the EGF receptor. J. Cell Biol. 2003, 162, 781-787.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 781-787
-
-
Kempiak, S.J.1
Yip, S.-C.2
Backer, J.M.3
Segall, J.E.4
-
52
-
-
0038732770
-
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation
-
Reynolds, A.R.; Tischer, C.; Verveer, P.J.; Rocks, O.; Bastiaens, P.I.H. EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation. Nat. Cell Biol. 2003, 5, 447-453.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 447-453
-
-
Reynolds, A.R.1
Tischer, C.2
Verveer, P.J.3
Rocks, O.4
Bastiaens, P.I.H.5
-
53
-
-
0034711405
-
Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane
-
Verveer, P.J.; Wouters, F.S.; Reynolds, A.R.; Bastiaens, P.I.H. Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane. Science 2000, 290, 1567-1570.
-
(2000)
Science
, vol.290
, pp. 1567-1570
-
-
Verveer, P.J.1
Wouters, F.S.2
Reynolds, A.R.3
Bastiaens, P.I.H.4
-
54
-
-
36248989579
-
Immobilized gradients of epidermal growth factor promote accelerated and directed keratinocyte migration
-
Stefonek, T.J.; Masters, K.S. Immobilized gradients of epidermal growth factor promote accelerated and directed keratinocyte migration. Wound Repair Regen. 2007, 15, 847-855.
-
(2007)
Wound Repair Regen.
, vol.15
, pp. 847-855
-
-
Stefonek, T.J.1
Masters, K.S.2
-
55
-
-
36349008570
-
Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparin-binding EGF-like growth factor protects cells from anoikis while maintainaing an epithelial phenotype
-
Singh, A.B.; Sugimoto, K.; Harris, R.C. Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparin-binding EGF-like growth factor protects cells from anoikis while maintainaing an epithelial phenotype. J. Biol. Chem. 2007, 282, 32890-32901.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32890-32901
-
-
Singh, A.B.1
Sugimoto, K.2
Harris, R.C.3
-
56
-
-
77955627615
-
Structural basis for negative cooperativity in growth factor binding to an EGF receptor
-
Alvarado, D.; Klein, D.E.; Lemmon, M.A. Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell 2010, 142, 568-579.
-
(2010)
Cell
, vol.142
, pp. 568-579
-
-
Alvarado, D.1
Klein, D.E.2
Lemmon, M.A.3
-
57
-
-
84863601338
-
A single ligand is sufficient to activate EGFR dimers
-
Liu, P.; Cleveland, T.E.T.; Bouyain, S.; Byrne, P.O.; Longo, P.A.; Leahy, D.J. A single ligand is sufficient to activate EGFR dimers. Proc. Natl. Acad. Sci. USA 2012, 109, 10861-10866.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 10861-10866
-
-
Liu, P.1
Cleveland, T.E.T.2
Bouyain, S.3
Byrne, P.O.4
Longo, P.A.5
Leahy, D.J.6
-
58
-
-
84868320002
-
Global snapshot of the influence of endocytosis upon EGF receptor signaling output
-
Omerovic, J.; Hammond, D.E.; Prior, I.A.; Clague, M.J. Global snapshot of the influence of endocytosis upon EGF receptor signaling output. J. Proteome Res. 2012, 11, 5157-5166.
-
(2012)
J. Proteome Res.
, vol.11
, pp. 5157-5166
-
-
Omerovic, J.1
Hammond, D.E.2
Prior, I.A.3
Clague, M.J.4
-
59
-
-
84866124328
-
Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation
-
Luwor, R.B.; Chin, X.; McGeachie, A.B.; Robinson, P.J.; Zhu, H.J. Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation. Growth Factors 2012, 30, 220-229.
-
(2012)
Growth Factors
, vol.30
, pp. 220-229
-
-
Luwor, R.B.1
Chin, X.2
McGeachie, A.B.3
Robinson, P.J.4
Zhu, H.J.5
-
60
-
-
0033607542
-
Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts
-
Haugh, J.M.; Huang, A.C.; Wiley, H.S.; Wells, A.; Lauffenburger, D.A. Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts. J. Biol. Chem. 1999, 274, 34350-343560.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34350-343560
-
-
Haugh, J.M.1
Huang, A.C.2
Wiley, H.S.3
Wells, A.4
Lauffenburger, D.A.5
-
61
-
-
0033605563
-
Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway
-
Haugh, J.M.; Schooler, K.; Wells, A.; Wiley, H.S.; Lauffenburger, D.A. Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway. J. Biol. Chem. 1999, 274, 8958-8965.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8958-8965
-
-
Haugh, J.M.1
Schooler, K.2
Wells, A.3
Wiley, H.S.4
Lauffenburger, D.A.5
-
62
-
-
84860165740
-
Mammalian MAPK signal transduction pathways activated by stress and inflammation: A 10-year update
-
Kyriakis, J.M.; Avruch, J. Mammalian MAPK signal transduction pathways activated by stress and inflammation: A 10-year update. Physiol. Rev. 2012, 92, 689-737.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 689-737
-
-
Kyriakis, J.M.1
Avruch, J.2
-
63
-
-
0031806620
-
Regulation of insulin receptor signaling pathways by clathrin mediated endocytosis
-
Ceresa, B.P.; Kao, A.W.; Santeler, S.R.; Pessin, J.E. Regulation of insulin receptor signaling pathways by clathrin mediated endocytosis. Mol. Cell. Biol. 1998, 18, 3862-3870.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3862-3870
-
-
Ceresa, B.P.1
Kao, A.W.2
Santeler, S.R.3
Pessin, J.E.4
-
64
-
-
51849163694
-
Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis
-
Galperin, E.; Sorkin, A. Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis. Traffic 2008, 9, 1776-1790.
-
(2008)
Traffic
, vol.9
, pp. 1776-1790
-
-
Galperin, E.1
Sorkin, A.2
-
65
-
-
0028046412
-
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
-
Printen, J.A.; Sprague, G.F., Jr. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 1994, 138, 609-619.
-
(1994)
Genetics
, vol.138
, pp. 609-619
-
-
Printen, J.A.1
Sprague Jr., G.F.2
-
66
-
-
84861000109
-
Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells
-
Galperin, E.; Abdelmoti, L.; Sorkin, A. Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells. PLoS One 2012, 7, e36469.
-
(2012)
PLoS One
, vol.7
-
-
Galperin, E.1
Abdelmoti, L.2
Sorkin, A.3
-
67
-
-
33644854068
-
Erbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complex
-
Dai, P.; Xiong, W.C.; Mei, L. Erbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complex. J. Biol. Chem. 2006, 281, 927-933.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 927-933
-
-
Dai, P.1
Xiong, W.C.2
Mei, L.3
-
68
-
-
84858174818
-
Regulation of the EGF transcriptional response by endocytic sorting
-
doi:10.1126/scisignal.2002351
-
Brankatschk, B.; Wichert, S.P.; Johnson, S.D.; Schaad, O.; Rossner, M.J.; Gruenberg, J. Regulation of the EGF transcriptional response by endocytic sorting. Sci. Signal. 2012, 5, doi:10.1126/scisignal.2002351.
-
(2012)
Sci. Signal.
, vol.5
-
-
Brankatschk, B.1
Wichert, S.P.2
Johnson, S.D.3
Schaad, O.4
Rossner, M.J.5
Gruenberg, J.6
-
69
-
-
84866326406
-
Differential regulation of transcription factors by location-specific EGF receptor signaling via a spatio-temporal interplay of ERK activation
-
Wu, P.; Wee, P.; Jiang, J.; Chen, X.; Wang, Z. Differential regulation of transcription factors by location-specific EGF receptor signaling via a spatio-temporal interplay of ERK activation. PLoS One 2012, 7, e41354.
-
(2012)
PLoS One
, vol.7
-
-
Wu, P.1
Wee, P.2
Jiang, J.3
Chen, X.4
Wang, Z.5
-
70
-
-
2342446235
-
Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells
-
Singh, A.B.; Tsukada, T.; Zent, R.; Harris, R.C. Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells. J. Cell Sci. 2004, 117, 1365-1379.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1365-1379
-
-
Singh, A.B.1
Tsukada, T.2
Zent, R.3
Harris, R.C.4
-
71
-
-
54249140899
-
Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells
-
Hyatt, D.C.; Ceresa, B.P. Cellular localization of the activated EGFR determines its effect on cell growth in MDA-MB-468 cells. Exp. Cell Res. 2008, 314, 3415-3425.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 3415-3425
-
-
Hyatt, D.C.1
Ceresa, B.P.2
-
72
-
-
0021804944
-
MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF
-
Filmus, J.; Pollak, M.N.; Cailleau, R.; Buick, R.N. MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF. Biochem. Biophys. Res. Commun. 1985, 128, 898-905.
-
(1985)
Biochem. Biophys. Res. Commun.
, vol.128
, pp. 898-905
-
-
Filmus, J.1
Pollak, M.N.2
Cailleau, R.3
Buick, R.N.4
-
73
-
-
84855275538
-
Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis
-
Rush, J.S.; Quinalty, L.M.; Engelman, L.; Sherry, D.M.; Ceresa, B.P. Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis. J. Biol. Chem. 2012, 287, 712-722.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 712-722
-
-
Rush, J.S.1
Quinalty, L.M.2
Engelman, L.3
Sherry, D.M.4
Ceresa, B.P.5
-
74
-
-
50349092363
-
Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis
-
Overmeyer, J.H.; Kaul, A.; Johnson, E.E.; Maltese, W.A. Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis. Mol. Cancer Res. 2008, 6, 965-977.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 965-977
-
-
Overmeyer, J.H.1
Kaul, A.2
Johnson, E.E.3
Maltese, W.A.4
-
75
-
-
84858032579
-
Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death
-
Robinson, M.W.; Overmeyer, J.H.; Young, A.M.; Erhardt, P.W.; Maltese, W.A. Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death. J. Med. Chem. 2012, 55, 1940-1956.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 1940-1956
-
-
Robinson, M.W.1
Overmeyer, J.H.2
Young, A.M.3
Erhardt, P.W.4
Maltese, W.A.5
-
76
-
-
79957854823
-
A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells
-
Overmeyer, J.H.; Young, A.M.; Bhanot, H.; Maltese, W.A. A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells. Mol. Cancer 2011, 10, 1-17.
-
(2011)
Mol. Cancer
, vol.10
, pp. 1-17
-
-
Overmeyer, J.H.1
Young, A.M.2
Bhanot, H.3
Maltese, W.A.4
|