Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Galperin, Emilia ^a   Abdelmoti, Lina ^a   Sorkin, Alexander ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLATHRIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; PROTEIN SHOC2; RAB7 PROTEIN; RAF PROTEIN; RAS PROTEIN; RECOMBINANT PROTEIN; RED FLUORESCENT PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; CLATHRIN HEAVY CHAIN; HYBRID PROTEIN; SHOC2 PROTEIN, HUMAN; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

ARTICLE; CELL FUNCTION; CELL STIMULATION; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; RNA INTERFERENCE; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; DRUG ANTAGONISM; GENETICS; HELA CELL; METABOLISM; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; CLATHRIN HEAVY CHAINS; COS CELLS; ENDOSOMES; EPIDERMAL GROWTH FACTOR; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MUTANT PROTEINS; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84861000109     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036469     Document Type: Article

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