Discovering some novel 7-chloroquinolines carrying a biologically active benzenesulfonamide moiety as a new class of anticancer agents

Chemical and Pharmaceutical Bulletin

Volumn 61, Issue 1, 2013, Pages 50-58

  Al Dosari, Mohammed Salem ^a   Ghorab, Mostafa Mohamed ^a   Al Said, Mansour Sulaiman ^a   Nissan, Yassin Mohammed ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Anticancer activity; Qunioline; Sulfonamide

Indexed keywords

4 (7 CHLOROQUINOLIN 4 YL AMINO) N (1 PHENYL 1H PYRAZOL 5 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (2,6 DIMETHOXY PYRIMIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (3 METHYL ISOXAZOL 5 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (3,4 DIMETHYLISOXAZOL 5 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (4 METHYL PYRIMIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (4,6 DIMETHYL PYRIMIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (5,6 DIMETHOXY PYRIMIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (PHENYLCARBAMOYL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (PYRIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (PYRIMIDIN 2 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO) N (THIAZOL 5 YL)BENZENESULFONAMIDE; 4 (7 CHLOROQUINOLIN 4 YL AMINO)BENZENESULFONAMIDE; 4 AMINO N (7 CHLOROQUINOLIN 4 YL)BENZENESULFONAMIDE; 7 CHLORO 4 ISOTHIOCYANATOQUINOLINE; ANTINEOPLASTIC AGENT; BENZENESULFONAMIDE DERIVATIVE; CHLOROQUINE; DOXORUBICIN; N (7 CHLOROQUINOLIN 4 YL) 4 (3 PHENYLUREIDO)BENZENESULFONAMIDE; N [4 (7 CHLOROQUINOLIN 4 YL AMINO)PHENYLSULFONYL]ACETAMIDE; N CARBAMIMIDOYL 4 (7 CHLOROQUINOLIN 4 YL AMINO)BENZENESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING KINETICS; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; NEUROBLASTOMA; SKIN CANCER; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; MODELS, MOLECULAR; NEOPLASMS; QUINOLINES; SULFONAMIDES;

EID: 84872199624     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00812     Document Type: Article

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