G2 arrest and apoptosis by 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound

Biochemical Pharmacology

Volumn 69, Issue 9, 2005, Pages 1333-1341

  Kim, Yun Hee ^a   Shin, Kum Joo ^a   Lee, Taehoon G ^b   Kim, Euikyung ^a   Lee, Myoung Shik ^c   Ryu, Sung Ho ^a   Suh, Pann Ghill ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Sigmol Incorporation   (South Korea)

^c Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Apoptosis; DNA damage; G2 arrest; Library screening; Quinolinesulfonamide

Indexed keywords

2 AMINO N QUINOLIN 8 YLBENZENESULFONAMIDE; 4 METHYL N 4 QUINOLINESULFONAMIDE; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; N 4 DIMETHYL N 8 QUINOLINYLBENZENESULFONAMIDE; N 8 QUINOLINYLBENZENESULFONAMIDE; N PHENYL 4 QUINOLINESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL CYCLE G2 PHASE; CELL SUBPOPULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIPLOIDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LONG TERM CARE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION;

EID: 17044419485     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.12.019     Document Type: Article

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