Utility of 4-(5,5-dimethyl-3-oxo-cyclohex-1-enylamino)benzenesulfonamide in the synthesis of novel quinolines as possible anticancer and radioprotective agents

Arzneimittel-Forschung/Drug Research

Volumn 58, Issue 1, 2008, Pages 35-41

  Ghorab, Mostafa M ^a   Ragab, Fatma A ^b   Noaman, Eman ^a   Heiba, Helmy I ^a   El Hossary, Ebaa M ^a  

^a NATIONAL CENTER FOR RADIATION RESEARCH AND TECHNOLOGY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Anticancer drugs; Quinolines, anticancer activity, radioprotective activity, sulfonamide moiety; Radioprotective drugs; Sulfonamides

Indexed keywords

4 (2 AMINO 3 CYANO 7,7 DIMETHYL 5 OXO 4 4 TOLYL 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL)BENZENESULFONAMIDE; 4 (2 AMINO 3 CYANO 7,7 DIMETHYL 5 OXO 4 PHENYL 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL)BENZENESULFONAMIDE; 4 (2 AMINO 3 CYANO 7,7 DIMETHYL 5 OXO 4 THIOPHEN 2 YL 5,6,7,8 TETRAHDYRO 4H QUINOLIN 1 YL) BENZENESULFONAMIDE; 4 (2 AMINO 3 CYANO 7,7 DIMETHYL 5 OXO 4 THIOPHEN 3 YL 5,6,7,8 TETRAHDYRO 4H QUINOLIN 1 YL) BENZENESULFONAMIDE; 4 (5,5 DIMETHYL 3 OXO CYLOHEX 1 ENYLAMINO)BENZENESULFONAMIDE; 4 [2 AMINO 3 (3 BROMO PHENYL) 3 CYANO 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 4 (2 METHOXY PHENYL) 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 4 (2,4 DICHLORO PHENYL) 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 4 (4 FLUORO PHENYL) 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 4 (4 HYDROXY PHENYL) 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 4 (4 METHOXY PHENYL) 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 7,7 DIMETHYL 4 (3 NITROPHENYL) 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 3 CYANO 7,7 DIMETHYL 4 (4 NITROPHENYL) 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 4 (2 CHLORO PHENYL) 3 CYANO 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 4 (4 BROMO PHENYL) 3 CYANO 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; 4 [2 AMINO 4 (4 CHLORO PHENYL) 3 CYANO 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H QUINOLIN 1 YL] BENZENESULFONAMIDE; ANTINEOPLASTIC AGENT; DOXORUBICIN; GLUTATHIONE; LIPID PEROXIDE; QUINOLONE DERIVATIVE; RADIOPROTECTIVE AGENT; SULFONAMIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; GAMMA IRRADIATION; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 38949207188     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296464     Document Type: Article

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