Effective treatment of mouse experimental colitis by alpha 2 integrin antibody: Comparison with alpha 4 antibody and conventional therapy

Acta Physiologica

Volumn 207, Issue 2, 2013, Pages 326-336

  Gillberg, L ^a   Berg, S ^a   de Verdier, P J ^b   Lindbom, L ^a   Werr, J ^a   Hellstrom P M ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

CD49b antigen; CD49d antigen; Dextran sulphate; Inflammatory bowel disease

Indexed keywords

ALPHA2 INTEGRIN ANTIBODY; ALPHA4 INTEGRIN ANTIBODY; AZATHIOPRINE; CXCL2 CHEMOKINE; DEXTRAN SULFATE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MESALAZINE; MESSENGER RNA; METHOTREXATE; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLOPATHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; HISTOLOGY; LEUKOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RECTUM HEMORRHAGE; REMISSION; TREATMENT DURATION; WEIGHT REDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; COLITIS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTEGRIN ALPHA2; INTEGRIN ALPHA4; MICE; MICE, INBRED BALB C; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84872190628     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12017     Document Type: Article

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