Long-term treatment with anti-α4 integrin antibodies aggravates colitis in Gαi2-deficient mice

European Journal of Immunology

Volumn 35, Issue 8, 2005, Pages 2274-2283

  Bjursten, Malin ^a   Bland, Paul W ^a,b   Willén, Roger ^c   Hörnquist, Elisabeth Hultgren ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell trafficking; Colitis; Inflammation; Mucosa; Rodent

Indexed keywords

ALPHA4 INTEGRIN; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HOMING RECEPTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CRL19.11; MONOCLONAL ANTIBODY DATK32; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOMA IN SITU; CELL PROLIFERATION; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG DOSE REGIMEN; DRUG MECHANISM; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; LONG TERM CARE; MOUSE; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; COLITIS; COLON; DISEASE MODELS, ANIMAL; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFLAMMATORY BOWEL DISEASES; INTEGRIN ALPHA4; LYMPHOID TISSUE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; SPLEEN; T-LYMPHOCYTES; TIME FACTORS;

EID: 23944465992     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200526022     Document Type: Article

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