메뉴 건너뛰기




Volumn 9, Issue 4, 2012, Pages 354-362

Prevalence and importance of comorbidities in patients with heart failure

Author keywords

Comorbidities; Heart failure; Inflammation

Indexed keywords

AMIODARONE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; THYROID HORMONE; VASOACTIVE AGENT;

EID: 84872189040     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-012-0110-z     Document Type: Article
Times cited : (38)

References (94)
  • 1
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2011 update: A report from the american heart association
    • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2011 update: A report from the american heart association. Circulation. 2011;123:e18-e209.
    • (2011) Circulation. , vol.123
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 2
    • 34249289422 scopus 로고    scopus 로고
    • Non-cardiac comorbidities in chronic heart failure
    • Lang CC, Mancini DM. Non-cardiac comorbidities in chronic heart failure. Heart. 2007;93:665-71.
    • (2007) Heart. , vol.93 , pp. 665-661
    • Lang, C.C.1    Mancini, D.M.2
  • 3
    • 84862562144 scopus 로고    scopus 로고
    • The cardiorenal syndrome in heart failure: Cardiac? Renal? Syndrome?
    • Interesting review article emphasizing the bidirectional associations between heart failure and coexisting morbidities and the lack of evidence regarding the presence of the cardiorenal syndrome
    • Triposkiadis F, Starling RC, Boudoulas H, et al. The cardiorenal syndrome in heart failure: Cardiac? Renal? Syndrome? Hear Fail Rev. 2012;17:355-66. Interesting review article emphasizing the bidirectional associations between heart failure and coexisting morbidities and the lack of evidence regarding the presence of the cardiorenal syndrome.
    • (2012) Hear Fail Rev. , vol.17 , pp. 355-356
    • Triposkiadis, F.1    Starling, R.C.2    Boudoulas, H.3
  • 4
    • 84857857236 scopus 로고    scopus 로고
    • Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
    • Important study which demonstrated a higher noncardiac comorbidity burden associated with higher non-heart failure (HF) hospitalizations in patients with HF and preserved (n02,843) vs. those with HF and depressed (n06,599) left ventricular ejection fraction during a 2-year follow-up
    • Ather S, Chan W, Bozkurt B, et al. Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction. J Am Coll Cardiol. 2012;59:998-1005. Important study which demonstrated a higher noncardiac comorbidity burden associated with higher non-heart failure (HF) hospitalizations in patients with HF and preserved (n02,843) vs. those with HF and depressed (n06,599) left ventricular ejection fraction during a 2-year follow-up.
    • (2012) J Am Coll Cardiol. , vol.59 , pp. 998-990
    • Ather, S.1    Chan, W.2    Bozkurt, B.3
  • 5
    • 0035678936 scopus 로고    scopus 로고
    • Pulmonary function test abnormalities in pulmonary vascular disease and chronic heart failure
    • Waxman AB. Pulmonary function test abnormalities in pulmonary vascular disease and chronic heart failure. Clinics in Chest Medicine. 2001;22:751-8. (Pubitemid 34020011)
    • (2001) Clinics in Chest Medicine , vol.22 , Issue.4 , pp. 751-758
    • Waxman, A.B.1
  • 6
    • 1242284319 scopus 로고    scopus 로고
    • The pulmonary manifestations of left heart failure
    • Gehlbach BK, Geppert E. The pulmonary manifestations of left heart failure. Chest. 2004;125:669-82.
    • (2004) Chest. , vol.125 , pp. 669-662
    • Gehlbach, B.K.1    Geppert, E.2
  • 8
    • 84856183215 scopus 로고    scopus 로고
    • Pulmonary hypertension predicts all-cause mortality in patients with heart failure: A retrospective cohort study
    • Record linkage study in Tayside, Scotland utilizing the Tayside echocardiogram database (>50,000 echocardiograms).Patients were included in the analysis if they had left ventricular systolic dysfunction, right ventricular systolic pressure (RVSP) measurement, and a loop diuretic prescription (provided not more than 1 year prior to echocardiogram). Pulmonary hypertension predicted all-cause mortality in this heterogeneous group of patients with heart failure with each 5 mmHg rise in RVSP was associated with a 6% increased risk of death
    • Szwejkowski BR, Elder DH, Shearer F, et al. Pulmonary hypertension predicts all-cause mortality in patients with heart failure: A retrospective cohort study. Eur J Hear Fail. 2012;14:162-7. Record linkage study in Tayside, Scotland utilizing the Tayside echocardiogram database (>50,000 echocardiograms).Patients were included in the analysis if they had left ventricular systolic dysfunction, right ventricular systolic pressure (RVSP) measurement, and a loop diuretic prescription (provided not more than 1 year prior to echocardiogram). Pulmonary hypertension predicted all-cause mortality in this heterogeneous group of patients with heart failure with each 5 mmHg rise in RVSP was associated with a 6% increased risk of death.
    • (2012) Eur J Hear Fail. , vol.14 , pp. 162-167
    • Szwejkowski, B.R.1    Elder, D.H.2    Shearer, F.3
  • 9
    • 84861526249 scopus 로고    scopus 로고
    • Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: Heart failure causes severe lung disease
    • Chen Y, Guo H, Xu D, Xu X, et al. Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: Heart failure causes severe lung disease. Hypertension. 2012;59:1170-8.
    • (2012) Hypertension. , vol.59 , pp. 1170-1178
    • Chen, Y.1    Guo, H.2    Xu, D.3    Xu, X.4
  • 10
    • 80052179132 scopus 로고    scopus 로고
    • Pulmonary hypertension associated with left heart disease: Characteristics, emerging concepts, and treatment strategies
    • Haddad F, Kudelko K, Mercier O, et al. Pulmonary hypertension associated with left heart disease: Characteristics, emerging concepts, and treatment strategies. Prog Cardiovasc Dis. 2011;54:154-67.
    • (2011) Prog Cardiovasc Dis. , vol.54 , pp. 154-157
    • Haddad, F.1    Kudelko, K.2    Mercier, O.3
  • 11
    • 84857375082 scopus 로고    scopus 로고
    • Bosentan effects on hemodynamics and clinical outcome in heart failure patients with pulmonary hypertension awaiting cardiac transplantation
    • Hefke T, Zittermann A, Fuchs U, et al. Bosentan effects on hemodynamics and clinical outcome in heart failure patients with pulmonary hypertension awaiting cardiac transplantation. Thorac Cardiovasc Surg. 2012;60:26-34.
    • (2012) Thorac Cardiovasc Surg. , vol.60 , pp. 26-24
    • Hefke, T.1    Zittermann, A.2    Fuchs, U.3
  • 12
    • 64549121146 scopus 로고    scopus 로고
    • Heart failure and chronic obstructive pulmonary disease: Diagnostic pitfalls and epidemiology
    • Hawkins NM, Petrie MC, Jhund PS, et al. Heart failure and chronic obstructive pulmonary disease: Diagnostic pitfalls and epidemiology. Eur J Hear Fail. 2009;11:130-9.
    • (2009) Eur J Hear Fail. , vol.11 , pp. 130-139
    • Hawkins, N.M.1    Petrie, M.C.2    Jhund, P.S.3
  • 13
    • 78649638728 scopus 로고    scopus 로고
    • Prognosis of heart failure patients with reduced and preserved ejection fraction and coexistent chronic obstructive pulmonary disease
    • This study demonstrated in 184 patients with coexistent heart failure (HF) and chronic obstructive pulmonary disease that cardiovascular and pulmonary event-free survival of HF with preserved left ventricular ejection fraction (LVEF) is similar to that of HF with depressed LVEF over 3 years follow-up
    • Kwon BJ, Kim DB, Jang SW, et al. Prognosis of heart failure patients with reduced and preserved ejection fraction and coexistent chronic obstructive pulmonary disease. Eur J Hear Fail. 2010;12:1339-44. This study demonstrated in 184 patients with coexistent heart failure (HF) and chronic obstructive pulmonary disease that cardiovascular and pulmonary event-free survival of HF with preserved left ventricular ejection fraction (LVEF) is similar to that of HF with depressed LVEF over 3 years follow-up.
    • (2010) Eur J Hear Fail. , vol.12 , pp. 1339-1334
    • Kwon, B.J.1    Kim, D.B.2    Jang, S.W.3
  • 14
    • 84864465267 scopus 로고    scopus 로고
    • Update in diagnosis and therapy of coexistent chronic obstructive pulmonary disease and chronic heart failure
    • Zeng Q, Jiang S. Update in diagnosis and therapy of coexistent chronic obstructive pulmonary disease and chronic heart failure. Journal of Thoracic Disease. 2012;4:310-5.
    • (2012) Journal of Thoracic Disease. , vol.4 , pp. 310-315
    • Zeng, Q.1    Jiang, S.2
  • 15
    • 30344480217 scopus 로고    scopus 로고
    • Pathogenesis of obstructive and central sleep apnoea
    • White DP. Pathogenesis of obstructive and central sleep apnoea. Am J Respir Crit Care Med. 2005;172:1363-70.
    • (2005) Am J Respir Crit Care Med. , vol.172 , pp. 1363-1360
    • White, D.P.1
  • 16
    • 78650914394 scopus 로고    scopus 로고
    • Obstructive sleep apnoea and heart failure: Pathophysiologic and therapeutic implications
    • Kasai T, Bradley TD. Obstructive sleep apnoea and heart failure: Pathophysiologic and therapeutic implications. J Am Coll Cardiol. 2011;57:119-27.
    • (2011) J Am Coll Cardiol. , vol.57 , pp. 119-117
    • Kasai, T.1    Bradley, T.D.2
  • 17
    • 0037426425 scopus 로고    scopus 로고
    • Sleep apnea and heart failure - Part II: Central sleep apnea
    • DOI 10.1161/01.CIR.0000061758.05044.64
    • Bradley TD, Floras JS. Sleep apnoea and heart failure: Part ii: Central sleep apnoea. Circulation. 2003;107:1822-6. (Pubitemid 36418366)
    • (2003) Circulation , vol.107 , Issue.13 , pp. 1822-1826
    • Bradley, T.D.1    Floras, J.S.2
  • 18
    • 84862976012 scopus 로고    scopus 로고
    • Central sleep apnoea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure
    • Prospective observational cohort study of hospitalized patients with systolic heart failure (n0784) evaluating the impact of sleep disordered breathing on cardiac readmissions. It demonstrated that central sleep apnoea (CSA) is an independent risk factor for 6 months' cardiac readmissions and that effect size of CSA exceeds that of all known predictors of heart failure readmissions
    • Khayat R, Abraham W, Patt B, et al. Central sleep apnoea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure. J Card Fail. 2012;18:534-40. Prospective observational cohort study of hospitalized patients with systolic heart failure (n0784) evaluating the impact of sleep disordered breathing on cardiac readmissions. It demonstrated that central sleep apnoea (CSA) is an independent risk factor for 6 months' cardiac readmissions and that effect size of CSA exceeds that of all known predictors of heart failure readmissions.
    • (2012) J Card Fail. , vol.18 , pp. 534-530
    • Khayat, R.1    Abraham, W.2    Patt, B.3
  • 19
    • 78649975790 scopus 로고    scopus 로고
    • Cheyne-stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverterdefibrillator therapies in patients with congestive heart failure
    • Large-scale long-Term study including 472 patients with congestive heart failure after implantation of a cardiac resynchronization device with cardioverter-defibrillator. It demonstrated an association between obstructive sleep apnoea and/or central sleep apnoea and risk for malignant cardiac arrhythmia
    • Bitter T, Westerheide N, Prinz C, et al. Cheyne-stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverterdefibrillator therapies in patients with congestive heart failure. Eur Hear J. 2011;32:61-74. Large-scale long-Term study including 472 patients with congestive heart failure after implantation of a cardiac resynchronization device with cardioverter- defibrillator. It demonstrated an association between obstructive sleep apnoea and/or central sleep apnoea and risk for malignant cardiac arrhythmia.
    • (2011) Eur Hear J. , vol.32 , pp. 61-64
    • Bitter, T.1    Westerheide, N.2    Prinz, C.3
  • 20
    • 84857400330 scopus 로고    scopus 로고
    • Treatment of cheyne-stokes respiration-central sleep apnoea in patients with heart failure
    • Momomura S. Treatment of Cheyne-Stokes respiration-central sleep apnoea in patients with heart failure. J Cardiol. 2012;59:110-6.
    • (2012) J Cardiol. , vol.59 , pp. 110-116
    • Momomura, S.1
  • 21
    • 84868143041 scopus 로고    scopus 로고
    • Adaptive servoventilation for treatment of sleep-disordered breathing in heart failure: A systematic review and meta-Analysis
    • Jun 21. [Epub ahead of print]. A systematic search including 14 studies (n0538) which demonstrated that adaptive servo-ventilation (ASV) in adult patients with heart failure and sleep disordered breathing reduces the apnoea/hypopnoea index and improves cardiac function and exercise capacity, providing a rationale for large-scale randomized controlled trials to assess the clinical impact of ASV on hard outcomes in these patients
    • Sharma BK, Bakker JP, McSharry DG, et al.: Adaptive servoventilation for treatment of sleep-disordered breathing in heart failure: A systematic review and meta-Analysis. Chest. 2012 Jun 21. [Epub ahead of print]. A systematic search including 14 studies (n0538) which demonstrated that adaptive servo-ventilation (ASV) in adult patients with heart failure and sleep disordered breathing reduces the apnoea/hypopnoea index and improves cardiac function and exercise capacity, providing a rationale for large-scale randomized controlled trials to assess the clinical impact of ASV on hard outcomes in these patients.
    • (2012) Chest
    • Sharma, B.K.1    Bakker, J.P.2    McSharry, D.G.3
  • 22
    • 77954521456 scopus 로고    scopus 로고
    • The effects of heart failure on renal function
    • Udani SM, Koyner JL. The effects of heart failure on renal function. Cardiol Clin. 2010;28:453-65.
    • (2010) Cardiol Clin. , vol.28 , pp. 453-455
    • Udani, S.M.1    Koyner, J.L.2
  • 23
    • 77953686335 scopus 로고    scopus 로고
    • Cardio-kidney-damage: A unifying concept
    • A rational theory which claims that the high prevalence of heart failure and chronic kidney disease in the elderly population is likely to reflect the underlying high prevalence of overt and subclinical atherosclerosis and cardiovascular disease
    • El Nahas M. Cardio-Kidney-Damage: a unifying concept. Kidney Int. 2010;78:14-8. A rational theory which claims that the high prevalence of heart failure and chronic kidney disease in the elderly population is likely to reflect the underlying high prevalence of overt and subclinical atherosclerosis and cardiovascular disease.
    • (2010) Kidney Int. , vol.78 , pp. 14-18
    • El Nahas, M.1
  • 24
    • 84861026739 scopus 로고    scopus 로고
    • The complexity of the cardio-renal link: Taxonomy, syndromes, and diseases
    • Review article emphasizing the lack of evidence regarding the presence of the cardiorenal syndrome
    • Zoccali C, Goldsmith D, Agarwal R, et al. The complexity of the cardio-renal link: taxonomy, syndromes, and diseases. Kidney International Supplements. 2011;1:2-5. Review article emphasizing the lack of evidence regarding the presence of the cardiorenal syndrome.
    • (2011) Kidney International Supplements. , vol.1 , pp. 2-5
    • Zoccali, C.1    Goldsmith, D.2    Agarwal, R.3
  • 25
    • 33646270387 scopus 로고    scopus 로고
    • Renal impairment and outcomes in heart failure: Systematic review and meta-Analysis
    • Smith GL, Lichtman JH, Bracken MB, et al. Renal impairment and outcomes in heart failure: Systematic review and meta-Analysis. J Am Coll Cardiol. 2006;47:1987-96.
    • (2006) J Am Coll Cardiol. , vol.47 , pp. 1987-1986
    • Smith, G.L.1    Lichtman, J.H.2    Bracken, M.B.3
  • 26
    • 37148999674 scopus 로고    scopus 로고
    • Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure
    • Gardner RS, Chong KS, O'Meara E, et al. Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure. Eur Hear J. 2007;28:3027-33.
    • (2007) Eur Hear J. , vol.28 , pp. 3027-3023
    • Gardner, R.S.1    Chong, K.S.2    O'Meara, E.3
  • 28
    • 78649448385 scopus 로고    scopus 로고
    • Impact of dopamine infusion on renal function in hospitalized heart failure patients: Results of the dopamine in acute decompensated heart failure (dad-hf) trial
    • Small study in patients with acutely decompensated heart failure which demostrated that the combination of low-dose furosemide and low-dose dopamine (5 μgkg-1min-1 continuous infusion for 8 hours) is equally effective as high-dose furosemide but associated with improved renal function profile and potassium homeostasis
    • Giamouzis G, Butler J, Starling RC, et al. Impact of dopamine infusion on renal function in hospitalized heart failure patients: Results of the dopamine in acute decompensated heart failure (DAD-HF) trial. J Card Fail. 2010;16:922-30. Small study in patients with acutely decompensated heart failure which demostrated that the combination of low-dose furosemide and low-dose dopamine (5 μgkg-1min-1 continuous infusion for 8 hours) is equally effective as high-dose furosemide but associated with improved renal function profile and potassium homeostasis.
    • (2010) J Card Fail. , vol.16 , pp. 922-920
    • Giamouzis, G.1    Butler, J.2    Starling, R.C.3
  • 29
    • 77952546653 scopus 로고    scopus 로고
    • Natural course and risk factors for impaired renal function during the first year after heart transplantation
    • Jokinen JJ, Tikkanen J, Kukkonen S, et al. Natural course and risk factors for impaired renal function during the first year after heart transplantation. Journal of Heart and Lung Transplantation. 2010;29:633-40.
    • (2010) Journal of Heart and Lung Transplantation. , vol.29 , pp. 633-630
    • Jokinen, J.J.1    Tikkanen, J.2    Kukkonen, S.3
  • 31
    • 80054724908 scopus 로고    scopus 로고
    • Effects of donor pretreatment with dopamine on survival after heart transplantation: A cohort study of heart transplant recipients nested in a randomized controlled multicenter trial
    • Benck U, Hoeger S, Brinkkoetter PT, et al. Effects of donor pretreatment with dopamine on survival after heart transplantation: A cohort study of heart transplant recipients nested in a randomized controlled multicenter trial. J Am Coll Cardiol. 2011;58:1768-77.
    • (2011) J Am Coll Cardiol. , vol.58 , pp. 1768-1767
    • Benck, U.1    Hoeger, S.2    Brinkkoetter, P.T.3
  • 32
    • 84855505229 scopus 로고    scopus 로고
    • Liver dysfunction in chronic heart failure: Prevalence, characteristics and prognostic significance
    • Poelzl G, Ess M, Mussner-Seeber C, et al. Liver dysfunction in chronic heart failure: Prevalence, characteristics and prognostic significance. Eur J Clin Investig. 2012;42:153-63.
    • (2012) Eur J Clin Investig. , vol.42 , pp. 153-153
    • Poelzl, G.1    Ess, M.2    Mussner-Seeber, C.3
  • 35
    • 64549161586 scopus 로고    scopus 로고
    • Liver function abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure: Assessment of reduction in mortality and morbidity (charm) program
    • Evaluation of prevalence and importance of liver function test (LFT) abnormalities in a large (n02679) cohort of heart failure patients. Elevated total bilirubin was the strongest LFT predictor of adverse outcome for both the composite outcome of cardiovascular death or heart failure hospitalization and allcause mortality
    • Allen LA, Felker GM, Pocock S, et al. Liver function abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure: Assessment of reduction in mortality and morbidity (charm) program. Eur J Hear Fail. 2009;11:170-7. Evaluation of prevalence and importance of liver function test (LFT) abnormalities in a large (n02679) cohort of heart failure patients. Elevated total bilirubin was the strongest LFT predictor of adverse outcome for both the composite outcome of cardiovascular death or heart failure hospitalization and allcause mortality.
    • (2009) Eur J Hear Fail. , vol.11 , pp. 170-177
    • Allen, L.A.1    Felker, G.M.2    Pocock, S.3
  • 36
    • 84857601881 scopus 로고    scopus 로고
    • Clinical course and predictive value of liver function tests in patients hospitalized for worsening heart failure with reduced ejection fraction: An analysis of the everest trial
    • Post-hoc analysis of the placebo group of the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan) trial including patients hospitalized for systolic heart failure which demonstrated that baseline and in-hospital changes in serum albumin and total billirubin provide additional prognostic value
    • Ambrosy AP, Vaduganathan M, Huffman MD, et al. Clinical course and predictive value of liver function tests in patients hospitalized for worsening heart failure with reduced ejection fraction: An analysis of the EVEREST trial. Eur J Hear Fail. 2012;14:302-11. Post-hoc analysis of the placebo group of the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan) trial including patients hospitalized for systolic heart failure which demonstrated that baseline and in-hospital changes in serum albumin and total billirubin provide additional prognostic value.
    • (2012) Eur J Hear Fail. , vol.14 , pp. 302-301
    • Ambrosy, A.P.1    Vaduganathan, M.2    Huffman, M.D.3
  • 37
    • 77953679829 scopus 로고    scopus 로고
    • Pathophysiology of anaemia in heart failure
    • Anand IS. Pathophysiology of anaemia in heart failure. Heart Failure Clinics. 2010;6:279-88.
    • (2010) Heart Failure Clinics. , vol.6 , pp. 279-278
    • Anand, I.S.1
  • 38
    • 37549048168 scopus 로고    scopus 로고
    • Relation of low hemoglobin and anaemia to morbidity and mortality in patients hospitalized with heart failure (insight from the optimize-hf registry)
    • Young JB, Abraham WT, Albert NM, et al. Relation of low hemoglobin and anaemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry). Am J Cardiol. 2008;101:223-30.
    • (2008) Am J Cardiol. , vol.101 , pp. 223-220
    • Young, J.B.1    Abraham, W.T.2    Albert, N.M.3
  • 39
    • 49849088979 scopus 로고    scopus 로고
    • Anaemia and mortality in heart failure patients: A systematic review and metaanalysis
    • Groenveld HF, Januzzi JL, Damman K, et al. Anaemia and mortality in heart failure patients: a systematic review and metaanalysis. J Am Coll Cardiol. 2008;52:818-27.
    • (2008) J Am Coll Cardiol. , vol.52 , pp. 818-817
    • Groenveld, H.F.1    Januzzi, J.L.2    Damman, K.3
  • 40
    • 64349107250 scopus 로고    scopus 로고
    • Prospective assessment of the occurrence of anaemia in patients with heart failure: Results from the study of anaemia in a heart failure population (stamina-hfp) registry
    • Adams Jr KF, Patterson JH, Oren RM, et al. Prospective assessment of the occurrence of anaemia in patients with heart failure: Results from the study of anaemia in a heart failure population (STAMINA-HFP) registry. Am Hear J. 2009;157:926-32.
    • (2009) Am Hear J. , vol.157 , pp. 926-922
    • Adams Jr., K.F.1    Patterson, J.H.2    Oren, R.M.3
  • 41
    • 33744477631 scopus 로고    scopus 로고
    • Anaemia in chronic heart failure: Prevalence, etiology, clinical correlates, and treatment options
    • Tang YD, Katz SD. Anaemia in chronic heart failure: Prevalence, etiology, clinical correlates, and treatment options. Circulation. 2006;113:2454-61.
    • (2006) Circulation. , vol.113 , pp. 2454-2451
    • Tang, Y.D.1    Katz, S.D.2
  • 42
    • 0037024202 scopus 로고    scopus 로고
    • Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure
    • DOI 10.1016/S0735-1097(02)01854-5, PII S0735109702018545
    • Horwich TB, Fonarow GC, Hamilton MA, et al. Anaemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J Am Coll Cardiol. 2002;39:1780-6. (Pubitemid 34595288)
    • (2002) Journal of the American College of Cardiology , vol.39 , Issue.11 , pp. 1780-1786
    • Horwich, T.B.1    Fonarow, G.C.2    Hamilton, M.A.3    MacLellan, W.R.4    Borenstein, J.5
  • 43
    • 77953572552 scopus 로고    scopus 로고
    • Mediators of anaemia in chronic heart failure
    • Le Jemtel TH, Arain S. Mediators of anaemia in chronic heart failure. Heart Failure Clinics. 2010;6:289-93.
    • (2010) Heart Failure Clinics. , vol.6 , pp. 289-283
    • Le Jemtel, T.H.1    Arain, S.2
  • 44
    • 78650692186 scopus 로고    scopus 로고
    • Hospitalization epidemic in patients with heart failure: Risk factors, risk prediction, knowledge gaps, and future directions
    • Giamouzis G, Kalogeropoulos A, Georgiopoulou V, et al. Hospitalization epidemic in patients with heart failure: Risk factors, risk prediction, knowledge gaps, and future directions. J Card Fail. 2011;17:54-75.
    • (2011) J Card Fail. , vol.17 , pp. 54-55
    • Giamouzis, G.1    Kalogeropoulos, A.2    Georgiopoulou, V.3
  • 45
    • 38349101846 scopus 로고    scopus 로고
    • Evaluation and long-Term prognosis of new-onset, transient, and persistent anaemia in ambulatory patients with chronic heart failure
    • TangWH, TongW, Jain A, et al. Evaluation and long-Term prognosis of new-onset, transient, and persistent anaemia in ambulatory patients with chronic heart failure. J Am Coll Cardiol. 2008;51:569-76.
    • (2008) J Am Coll Cardiol. , vol.51 , pp. 569-566
    • Tang, W.H.1    Tong, W.2    Jain, A.3
  • 46
    • 84872189898 scopus 로고    scopus 로고
    • Anaemia in heart failure patients
    • Epub 2012 Mar 25
    • Alexandrakis MG, Tsirakis G. Anaemia in heart failure patients. ISRN Hematology. 2012;2012:246915. Epub 2012 Mar 25.
    • (2012) ISRN Hematology. , vol.2012 , pp. 246915
    • Alexandrakis, M.G.1    Tsirakis, G.2
  • 48
    • 0026755208 scopus 로고
    • Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism
    • Ladenson PW, Sherman SI, Baughman KL, et al. Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism. Proc Natl Acad Sci U S A. 1992;89:5251-5.
    • (1992) Proc Natl Acad Sci U S A. , vol.89 , pp. 5251-5255
    • Ladenson, P.W.1    Sherman, S.I.2    Baughman, K.L.3
  • 50
    • 77955130680 scopus 로고    scopus 로고
    • Thyroid replacement therapy and heart failure
    • Gerdes AM, Iervasi G. Thyroid replacement therapy and heart failure. Circulation. 2010;122:385-93.
    • (2010) Circulation. , vol.122 , pp. 385-383
    • Gerdes, A.M.1    Iervasi, G.2
  • 51
    • 73949103448 scopus 로고    scopus 로고
    • Effects of amiodarone therapy on thyroid function
    • Review paper on the pathophyiology identification, and management of amidarone-induced thyroid abnormalities in patients with heart failure
    • Cohen-Lehman J, Dahl P, Danzi S, Klein I. Effects of amiodarone therapy on thyroid function. Nature reviews Endocrinology. 2010;6:34-41. Review paper on the pathophyiology identification, and management of amidarone-induced thyroid abnormalities in patients with heart failure.
    • (2010) Nature reviews Endocrinology. , vol.6 , pp. 34-31
    • Cohen-Lehman, J.1    Dahl, P.2    Danzi, S.3    Klein, I.4
  • 53
    • 29344440492 scopus 로고    scopus 로고
    • Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: A report from the acute decompensated heart failure national registry (adhere) database
    • Yancy CW, Lopatin M, Stevenson LW, et al. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: A report from the acute decompensated heart failure national registry (ADHERE) database. J Am Coll Cardiol. 2006;47:76-84.
    • (2006) J Am Coll Cardiol. , vol.47 , pp. 76-74
    • Yancy, C.W.1    Lopatin, M.2    Stevenson, L.W.3
  • 54
    • 44949172981 scopus 로고    scopus 로고
    • Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: An analysis of the candesartan in heart failure: Assessment of reduction in mortality and morbidity (charm) programme
    • MacDonald MR, Petrie MC, Varyani F, et al. Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: An analysis of the candesartan in heart failure: Assessment of reduction in mortality and morbidity (CHARM) programme. Eur Hear J. 2008;29:1377-85.
    • (2008) Eur Hear J. , vol.29 , pp. 1377-1375
    • MacDonald, M.R.1    Petrie, M.C.2    Varyani, F.3
  • 55
    • 65249170100 scopus 로고    scopus 로고
    • Heart failure due to systolic dysfunction and mortality in diabetes: Pooled analysis of 39,505 subjects
    • Kamalesh M, Cleophas TJ. Heart failure due to systolic dysfunction and mortality in diabetes: Pooled analysis of 39,505 subjects. J Card Fail. 2009;15:305-9.
    • (2009) J Card Fail. , vol.15 , pp. 305-309
    • Kamalesh, M.1    Cleophas, T.J.2
  • 56
    • 60449096969 scopus 로고    scopus 로고
    • Insulin resistance is highly prevalent and is associated with reduced exercise tolerance in nondiabetic patients with heart failure
    • This study demonstrated in a cohort of 129 consecutive nondiabetic heart failure patients that 61% suffer from insulin resistance (IR), IR increases significantly with worsening New York Heart Association functional class, and that the presence of IR is associated with a significantly lower exercise capacity and peak oxygen consumption
    • Al Zadjali MA, Godfrey V, Khan F, et al. Insulin resistance is highly prevalent and is associated with reduced exercise tolerance in nondiabetic patients with heart failure. J Am Coll Cardiol. 2009;53:747-53. This study demonstrated in a cohort of 129 consecutive nondiabetic heart failure patients that 61% suffer from insulin resistance (IR), IR increases significantly with worsening New York Heart Association functional class, and that the presence of IR is associated with a significantly lower exercise capacity and peak oxygen consumption.
    • (2009) J Am Coll Cardiol. , vol.53 , pp. 747-743
    • Al Zadjali, M.A.1    Godfrey, V.2    Khan, F.3
  • 58
    • 34548603259 scopus 로고    scopus 로고
    • Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: Systematic review
    • Epub 2007 Aug 30
    • Eurich DT, McAlister FA, Blackburn DF, et al. Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: Systematic review. British Medical Journal. 2007;335(7618):497. Epub 2007 Aug 30.
    • (2007) British Medical Journal. , vol.335 , Issue.7618 , pp. 497
    • Eurich, D.T.1    McAlister, F.A.2    Blackburn, D.F.3
  • 59
    • 10744221639 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure: A consensus statement from the american heart association and american diabetes association
    • Nesto RW, Bell D, Bonow RO, et al. Thiazolidinedione use, fluid retention, and congestive heart failure: A consensus statement from the American Heart Association and American Diabetes Association. Diabetes Care. 2004;27:256-63.
    • (2004) Diabetes Care. , vol.27 , pp. 256-253
    • Nesto, R.W.1    Bell, D.2    Bonow, R.O.3
  • 62
    • 77957886583 scopus 로고    scopus 로고
    • Advances in understanding and treating cardiac cachexia: Highlights from the 5th cachexia conference
    • von Haehling S, Stepney R, Anker SD. Advances in understanding and treating cardiac cachexia: Highlights from the 5th cachexia conference. Int J Cardiol. 2010;144:347-9.
    • (2010) Int J Cardiol. , vol.144 , pp. 347-349
    • Von Haehling, S.1    Stepney, R.2    Anker, S.D.3
  • 63
    • 37249042851 scopus 로고    scopus 로고
    • Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training
    • Duscha BD, Schulze PC, Robbins JL, Forman DE. Implications of chronic heart failure on peripheral vasculature and skeletal muscle before and after exercise training. Hear Fail Rev. 2008;13:21-37.
    • (2008) Hear Fail Rev. , vol.13 , pp. 21-27
    • Duscha, B.D.1    Schulze, P.C.2    Robbins, J.L.3    Forman, D.E.4
  • 64
    • 0035875771 scopus 로고    scopus 로고
    • Skeletal muscle mass independently predicts peak oxygen consumption and ventilatory response during exercise in noncachectic patients with chronic heart failure
    • DOI 10.1016/S0735-1097(01)01306-7, PII S0735109701013067
    • Cicoira M, Zanolla L, Franceschini L, et al. Skeletal muscle mass independently predicts peak oxygen consumption and ventilatory response during exercise in noncachectic patients with chronic heart failure. J Am Coll Cardiol. 2001;37:2080-5. (Pubitemid 32548001)
    • (2001) Journal of the American College of Cardiology , vol.37 , Issue.8 , pp. 2080-2085
    • Cicoira, M.1    Zanolla, L.2    Franceschini, L.3    Rossi, A.4    Golia, G.5    Zamboni, M.6    Tosoni, P.7    Zardini, P.8
  • 65
    • 0030297046 scopus 로고    scopus 로고
    • The "muscle hypothesis" of chronic heart failure
    • Coats AJ. The "muscle hypothesis" of chronic heart failure. J Mol Cell Cardiol. 1996;28:2255-62.
    • (1996) J Mol Cell Cardiol. , vol.28 , pp. 2255-2252
    • Coats, A.J.1
  • 66
    • 84862564658 scopus 로고    scopus 로고
    • Intrinsic skeletal muscle alterations in chronic heart failure patients: A disease-specific myopathy or a result of deconditioning?
    • Critical review of the evidence for skeletal muscle alterations in CHF, the underlying mechanisms of such alterations and how skeletal muscle responds to training in this patient group
    • Rehn TA, Munkvik M, Lunde PK, et al. Intrinsic skeletal muscle alterations in chronic heart failure patients: A disease-specific myopathy or a result of deconditioning? Hear Fail Rev. 2012;17:421-36. Critical review of the evidence for skeletal muscle alterations in CHF, the underlying mechanisms of such alterations and how skeletal muscle responds to training in this patient group.
    • (2012) Hear Fail Rev. , vol.17 , pp. 421-426
    • Rehn, T.A.1    Munkvik, M.2    Lunde, P.K.3
  • 67
    • 33749531197 scopus 로고    scopus 로고
    • Depression in heart failure a meta-Analytic review of prevalence, intervention effects, and associations with clinical outcomes
    • Rutledge T, Reis VA, Linke SE, et al. Depression in heart failure a meta-Analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006;48:1527-37.
    • (2006) J Am Coll Cardiol. , vol.48 , pp. 1527-1527
    • Rutledge, T.1    Reis, V.A.2    Linke, S.E.3
  • 68
    • 0031822289 scopus 로고    scopus 로고
    • The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
    • Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment. Arch Gen Psychiatry. 1998;55:580-92.
    • (1998) Arch Gen Psychiatry. , vol.55 , pp. 580-582
    • Musselman, D.L.1    Evans, D.L.2    Nemeroff, C.B.3
  • 69
    • 0034881130 scopus 로고    scopus 로고
    • Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure
    • Jiang W, Alexander J, Christopher E, et al. Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med. 2001;161:1849-56.
    • (2001) Arch Intern Med. , vol.161 , pp. 1849-1846
    • Jiang, W.1    Alexander, J.2    Christopher, E.3
  • 70
    • 63049092819 scopus 로고    scopus 로고
    • Depression and clinical outcomes in heart failure: An optimize-hf analysis
    • Albert NM, Fonarow GC, Abraham WT, et al. Depression and clinical outcomes in heart failure: An OPTIMIZE-HF analysis. Am J Med. 2009;122:366-73.
    • (2009) Am J Med. , vol.122 , pp. 366-363
    • Albert, N.M.1    Fonarow, G.C.2    Abraham, W.T.3
  • 72
    • 77955862043 scopus 로고    scopus 로고
    • Safety and efficacy of sertraline for depression in patients with heart failure: Results of the sadhart-chf (sertraline against depression and heart disease in chronic heart failure) trial
    • The SADHART-CHF trial was a randomized, double-blind, placebocontrolled trial of sertraline 50 to 200 mg/day (n0234) versus matching placebo (n0235) for 12 weeks in patients with systolic heart failure and clinical depression. Although, sertraline was safe, it did not provide greater reduction in depression or improved cardiovascular status among patients with HF and depression
    • O'Connor CM, Jiang W, Kuchibhatla M, et al. Safety and efficacy of sertraline for depression in patients with heart failure: Results of the SADHART-CHF (sertraline against depression and heart disease in chronic heart failure) trial. J Am Coll Cardiol. 2010;56:692-9. The SADHART-CHF trial was a randomized, double-blind, placebocontrolled trial of sertraline 50 to 200 mg/day (n0234) versus matching placebo (n0235) for 12 weeks in patients with systolic heart failure and clinical depression. Although, sertraline was safe, it did not provide greater reduction in depression or improved cardiovascular status among patients with HF and depression.
    • (2010) J Am Coll Cardiol. , vol.56 , pp. 692-699
    • O'Connor, C.M.1    Jiang, W.2    Kuchibhatla, M.3
  • 74
    • 35748969276 scopus 로고    scopus 로고
    • Profile of cognitive impairment in chronic heart failure
    • Vogels RL, Oosterman JM, van Harten B, et al. Profile of cognitive impairment in chronic heart failure. J Am Geriatr Soc. 2007;55:1764-70.
    • (2007) J Am Geriatr Soc. , vol.55 , pp. 1764-1760
    • Vogels, R.L.1    Oosterman, J.M.2    Van Harten, B.3
  • 75
    • 1642471668 scopus 로고    scopus 로고
    • Cognitive impairment: A key feature of congestive heart failure in the elderly
    • Trojano L. Antonelli Incalzi R, Acanfora D, et al.: Cognitive impairment: A key feature of congestive heart failure in the elderly. J Neurol. 2003;250:1456-63.
    • (2003) J Neurol. , vol.250 , pp. 1456-1453
    • Trojano, L.1    Antonelli Incalzi, R.2    Acanfora, D.3
  • 76
    • 13544250575 scopus 로고    scopus 로고
    • Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure
    • Zuccala G, Onder G, Marzetti E, et al. Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure. Eur Hear J. 2005;26:226-33.
    • (2005) Eur Hear J. , vol.26 , pp. 226-223
    • Zuccala, G.1    Onder, G.2    Marzetti, E.3
  • 78
    • 67649397446 scopus 로고    scopus 로고
    • Inflammation in chronic kidney disease: Role in the progression of renal and cardiovascular disease
    • Silverstein DM. Inflammation in chronic kidney disease: Role in the progression of renal and cardiovascular disease. Pediatr Nephrol. 2009;24:1445-52.
    • (2009) Pediatr Nephrol. , vol.24 , pp. 1445-1442
    • Silverstein, D.M.1
  • 79
    • 50049130554 scopus 로고    scopus 로고
    • Oxidative stress, inflammation and cardiovascular disease in chronic renal failure
    • Cottone S, Lorito MC, Riccobene R, et al. Oxidative stress, inflammation and cardiovascular disease in chronic renal failure. Journal of Nephrology. 2008;21:175-9.
    • (2008) Journal of Nephrology. , vol.21 , pp. 175-179
    • Cottone, S.1    Lorito, M.C.2    Riccobene, R.3
  • 80
    • 70349873349 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and obstructive sleep apnoea: Overlaps in pathophysiology, systemic inflammation, and cardiovascular disease
    • McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnoea: Overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med. 2009;180:692-700.
    • (2009) Am J Respir Crit Care Med. , vol.180 , pp. 692-690
    • McNicholas, W.T.1
  • 81
    • 27444448072 scopus 로고    scopus 로고
    • Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
    • DOI 10.1161/CIRCULATIONAHA.105.556746
    • Ryan S, Taylor CT, McNicholas WT. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnoea syndrome. Circulation. 2005;112:2660-7. (Pubitemid 41532603)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2660-2667
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 82
    • 79954596966 scopus 로고    scopus 로고
    • Liver x receptors in atherosclerosis and inflammation
    • Im SS, Osborne TF. Liver x receptors in atherosclerosis and inflammation. Circ Res. 2011;108:996-1001.
    • (2011) Circ Res. , vol.108 , pp. 996-990
    • Im, S.S.1    Osborne, T.F.2
  • 83
    • 33847363203 scopus 로고    scopus 로고
    • Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ
    • Iredale JP. Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ. The Journal of Cclinical Investigation. 2007;117:539-48.
    • (2007) The Journal of Cclinical Investigation. , vol.117 , pp. 539-538
    • Iredale, J.P.1
  • 84
    • 0025000652 scopus 로고
    • Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
    • Maher JJ, McGuire RF. Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest. 1990;86:1641-8. (Pubitemid 20372615)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.5 , pp. 1641-1648
    • Maher, J.J.1    McGuire, R.F.2
  • 86
    • 84864352214 scopus 로고    scopus 로고
    • Inflammation and anaemia in a broad spectrum of patients with heart failure
    • Jun 22. [Epub ahead of print]. Multicentre randomised clinical trial including patients admitted for heart failure (n0326), which demonstrated that anaemia (Hb <13 g/dl (men) and <12 g/dl (women)) was present in 40% (130/326) of the study population and that that the levels of IL-6, hsCRP and sTNFR-1 were significantly higher in anaemic than in non-Anaemic patients emphasizing the association between anaemia and inflammation
    • Kleijn L, Belonje AM, Voors AA, et al.: Inflammation and anaemia in a broad spectrum of patients with heart failure. Heart. 2012 Jun 22. [Epub ahead of print]. Multicentre randomised clinical trial including patients admitted for heart failure (n0326), which demonstrated that anaemia (Hb <13 g/dl (men) and <12 g/dl (women)) was present in 40% (130/326) of the study population and that that the levels of IL-6, hsCRP and sTNFR-1 were significantly higher in anaemic than in non-Anaemic patients emphasizing the association between anaemia and inflammation.
    • (2012) Heart.
    • Kleijn, L.1    Belonje, A.M.2    Voors, A.A.3
  • 87
    • 78649442666 scopus 로고    scopus 로고
    • Diabetes and inflammation: Fundamental aspects and clinical implications
    • Garcia C, Feve B, Ferre P, et al. Diabetes and inflammation: Fundamental aspects and clinical implications. Diabetes & Metabolism. 2010;36:327-38.
    • (2010) Diabetes & Metabolism. , vol.36 , pp. 327-328
    • Garcia, C.1    Feve, B.2    Ferre, P.3
  • 88
    • 70449394029 scopus 로고    scopus 로고
    • Pancreatic islet inflammation in type 2 diabetes: From alpha and beta cell compensation to dysfunction
    • Ehses JA, Ellingsgaard H, Boni-Schnetzler M, DonathMY. Pancreatic islet inflammation in type 2 diabetes: From alpha and beta cell compensation to dysfunction. Arch Physiol Biochem. 2009;115:240-7.
    • (2009) Arch Physiol Biochem. , vol.115 , pp. 240-247
    • Ehses, J.A.1    Ellingsgaard, H.2    Boni-Schnetzler, M.3    Donath, M.Y.4
  • 90
    • 0033558684 scopus 로고    scopus 로고
    • Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance
    • Adams V, Jiang H, Yu J, et al. Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance. J Am Coll Cardiol. 1999;33:959-65.
    • (1999) J Am Coll Cardiol. , vol.33 , pp. 959-955
    • Adams, V.1    Jiang, H.2    Yu, J.3
  • 92
    • 0027921994 scopus 로고
    • Neuroendocrine-immune interactions
    • Reichlin S. Neuroendocrine-immune interactions. N Engl J Med. 1993;329:1246-53.
    • (1993) N Engl J Med. , vol.329 , pp. 1246-1243
    • Reichlin, S.1
  • 94
    • 78149245073 scopus 로고    scopus 로고
    • Role of inflammation in cognitive impairment: Results of observational epidemiological studies and clinical trials
    • Review of the observations that have led to the establishment of an association of systemic and brain inflammatory markers on cognitive impairment and dementia
    • Gorelick PB. Role of inflammation in cognitive impairment: Results of observational epidemiological studies and clinical trials. Ann N Y Acad Sci. 2010;1207:155-62. Review of the observations that have led to the establishment of an association of systemic and brain inflammatory markers on cognitive impairment and dementia.
    • (2010) Ann N Y Acad Sci. , vol.1207 , pp. 155-152
    • Gorelick, P.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.