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1
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79751531393
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Heart disease and stroke statistics-2011 update: A report from the american heart association
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Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2011 update: A report from the american heart association. Circulation. 2011;123:e18-e209.
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Roger, V.L.1
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Lang CC, Mancini DM. Non-cardiac comorbidities in chronic heart failure. Heart. 2007;93:665-71.
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Lang, C.C.1
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The cardiorenal syndrome in heart failure: Cardiac? Renal? Syndrome?
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Interesting review article emphasizing the bidirectional associations between heart failure and coexisting morbidities and the lack of evidence regarding the presence of the cardiorenal syndrome
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Triposkiadis F, Starling RC, Boudoulas H, et al. The cardiorenal syndrome in heart failure: Cardiac? Renal? Syndrome? Hear Fail Rev. 2012;17:355-66. Interesting review article emphasizing the bidirectional associations between heart failure and coexisting morbidities and the lack of evidence regarding the presence of the cardiorenal syndrome.
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Hear Fail Rev.
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Triposkiadis, F.1
Starling, R.C.2
Boudoulas, H.3
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4
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84857857236
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Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
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Important study which demonstrated a higher noncardiac comorbidity burden associated with higher non-heart failure (HF) hospitalizations in patients with HF and preserved (n02,843) vs. those with HF and depressed (n06,599) left ventricular ejection fraction during a 2-year follow-up
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Ather S, Chan W, Bozkurt B, et al. Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction. J Am Coll Cardiol. 2012;59:998-1005. Important study which demonstrated a higher noncardiac comorbidity burden associated with higher non-heart failure (HF) hospitalizations in patients with HF and preserved (n02,843) vs. those with HF and depressed (n06,599) left ventricular ejection fraction during a 2-year follow-up.
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Ather, S.1
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Waxman AB. Pulmonary function test abnormalities in pulmonary vascular disease and chronic heart failure. Clinics in Chest Medicine. 2001;22:751-8. (Pubitemid 34020011)
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Clinics in Chest Medicine
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Gehlbach, B.K.1
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DOI 10.1016/S0002-9149(98)00784-X, PII S000291499800784X
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Mettauer B, Lampert E, Charloux A, et al. Lung membrane diffusing capacity, heart failure, and heart transplantation. Am J Cardiol. 1999;83:62-7. (Pubitemid 29036649)
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Mettauer, B.1
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84856183215
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Pulmonary hypertension predicts all-cause mortality in patients with heart failure: A retrospective cohort study
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Record linkage study in Tayside, Scotland utilizing the Tayside echocardiogram database (>50,000 echocardiograms).Patients were included in the analysis if they had left ventricular systolic dysfunction, right ventricular systolic pressure (RVSP) measurement, and a loop diuretic prescription (provided not more than 1 year prior to echocardiogram). Pulmonary hypertension predicted all-cause mortality in this heterogeneous group of patients with heart failure with each 5 mmHg rise in RVSP was associated with a 6% increased risk of death
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Szwejkowski BR, Elder DH, Shearer F, et al. Pulmonary hypertension predicts all-cause mortality in patients with heart failure: A retrospective cohort study. Eur J Hear Fail. 2012;14:162-7. Record linkage study in Tayside, Scotland utilizing the Tayside echocardiogram database (>50,000 echocardiograms).Patients were included in the analysis if they had left ventricular systolic dysfunction, right ventricular systolic pressure (RVSP) measurement, and a loop diuretic prescription (provided not more than 1 year prior to echocardiogram). Pulmonary hypertension predicted all-cause mortality in this heterogeneous group of patients with heart failure with each 5 mmHg rise in RVSP was associated with a 6% increased risk of death.
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Szwejkowski, B.R.1
Elder, D.H.2
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9
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Chen Y, Guo H, Xu D, Xu X, et al. Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: Heart failure causes severe lung disease. Hypertension. 2012;59:1170-8.
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Haddad F, Kudelko K, Mercier O, et al. Pulmonary hypertension associated with left heart disease: Characteristics, emerging concepts, and treatment strategies. Prog Cardiovasc Dis. 2011;54:154-67.
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Hefke T, Zittermann A, Fuchs U, et al. Bosentan effects on hemodynamics and clinical outcome in heart failure patients with pulmonary hypertension awaiting cardiac transplantation. Thorac Cardiovasc Surg. 2012;60:26-34.
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Hawkins NM, Petrie MC, Jhund PS, et al. Heart failure and chronic obstructive pulmonary disease: Diagnostic pitfalls and epidemiology. Eur J Hear Fail. 2009;11:130-9.
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Hawkins, N.M.1
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13
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78649638728
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Prognosis of heart failure patients with reduced and preserved ejection fraction and coexistent chronic obstructive pulmonary disease
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This study demonstrated in 184 patients with coexistent heart failure (HF) and chronic obstructive pulmonary disease that cardiovascular and pulmonary event-free survival of HF with preserved left ventricular ejection fraction (LVEF) is similar to that of HF with depressed LVEF over 3 years follow-up
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Kwon BJ, Kim DB, Jang SW, et al. Prognosis of heart failure patients with reduced and preserved ejection fraction and coexistent chronic obstructive pulmonary disease. Eur J Hear Fail. 2010;12:1339-44. This study demonstrated in 184 patients with coexistent heart failure (HF) and chronic obstructive pulmonary disease that cardiovascular and pulmonary event-free survival of HF with preserved left ventricular ejection fraction (LVEF) is similar to that of HF with depressed LVEF over 3 years follow-up.
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Kwon, B.J.1
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Zeng Q, Jiang S. Update in diagnosis and therapy of coexistent chronic obstructive pulmonary disease and chronic heart failure. Journal of Thoracic Disease. 2012;4:310-5.
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DOI 10.1161/01.CIR.0000061758.05044.64
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Bradley TD, Floras JS. Sleep apnoea and heart failure: Part ii: Central sleep apnoea. Circulation. 2003;107:1822-6. (Pubitemid 36418366)
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Bradley, T.D.1
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84862976012
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Central sleep apnoea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure
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Prospective observational cohort study of hospitalized patients with systolic heart failure (n0784) evaluating the impact of sleep disordered breathing on cardiac readmissions. It demonstrated that central sleep apnoea (CSA) is an independent risk factor for 6 months' cardiac readmissions and that effect size of CSA exceeds that of all known predictors of heart failure readmissions
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Khayat R, Abraham W, Patt B, et al. Central sleep apnoea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure. J Card Fail. 2012;18:534-40. Prospective observational cohort study of hospitalized patients with systolic heart failure (n0784) evaluating the impact of sleep disordered breathing on cardiac readmissions. It demonstrated that central sleep apnoea (CSA) is an independent risk factor for 6 months' cardiac readmissions and that effect size of CSA exceeds that of all known predictors of heart failure readmissions.
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J Card Fail.
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Khayat, R.1
Abraham, W.2
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19
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78649975790
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Cheyne-stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverterdefibrillator therapies in patients with congestive heart failure
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Large-scale long-Term study including 472 patients with congestive heart failure after implantation of a cardiac resynchronization device with cardioverter-defibrillator. It demonstrated an association between obstructive sleep apnoea and/or central sleep apnoea and risk for malignant cardiac arrhythmia
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Bitter T, Westerheide N, Prinz C, et al. Cheyne-stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverterdefibrillator therapies in patients with congestive heart failure. Eur Hear J. 2011;32:61-74. Large-scale long-Term study including 472 patients with congestive heart failure after implantation of a cardiac resynchronization device with cardioverter- defibrillator. It demonstrated an association between obstructive sleep apnoea and/or central sleep apnoea and risk for malignant cardiac arrhythmia.
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Bitter, T.1
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Momomura S. Treatment of Cheyne-Stokes respiration-central sleep apnoea in patients with heart failure. J Cardiol. 2012;59:110-6.
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Jun 21. [Epub ahead of print]. A systematic search including 14 studies (n0538) which demonstrated that adaptive servo-ventilation (ASV) in adult patients with heart failure and sleep disordered breathing reduces the apnoea/hypopnoea index and improves cardiac function and exercise capacity, providing a rationale for large-scale randomized controlled trials to assess the clinical impact of ASV on hard outcomes in these patients
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Sharma BK, Bakker JP, McSharry DG, et al.: Adaptive servoventilation for treatment of sleep-disordered breathing in heart failure: A systematic review and meta-Analysis. Chest. 2012 Jun 21. [Epub ahead of print]. A systematic search including 14 studies (n0538) which demonstrated that adaptive servo-ventilation (ASV) in adult patients with heart failure and sleep disordered breathing reduces the apnoea/hypopnoea index and improves cardiac function and exercise capacity, providing a rationale for large-scale randomized controlled trials to assess the clinical impact of ASV on hard outcomes in these patients.
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(2012)
Chest
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Sharma, B.K.1
Bakker, J.P.2
McSharry, D.G.3
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22
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Udani SM, Koyner JL. The effects of heart failure on renal function. Cardiol Clin. 2010;28:453-65.
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Udani, S.M.1
Koyner, J.L.2
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23
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77953686335
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Cardio-kidney-damage: A unifying concept
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A rational theory which claims that the high prevalence of heart failure and chronic kidney disease in the elderly population is likely to reflect the underlying high prevalence of overt and subclinical atherosclerosis and cardiovascular disease
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El Nahas M. Cardio-Kidney-Damage: a unifying concept. Kidney Int. 2010;78:14-8. A rational theory which claims that the high prevalence of heart failure and chronic kidney disease in the elderly population is likely to reflect the underlying high prevalence of overt and subclinical atherosclerosis and cardiovascular disease.
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El Nahas, M.1
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24
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84861026739
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Review article emphasizing the lack of evidence regarding the presence of the cardiorenal syndrome
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Zoccali C, Goldsmith D, Agarwal R, et al. The complexity of the cardio-renal link: taxonomy, syndromes, and diseases. Kidney International Supplements. 2011;1:2-5. Review article emphasizing the lack of evidence regarding the presence of the cardiorenal syndrome.
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Smith GL, Lichtman JH, Bracken MB, et al. Renal impairment and outcomes in heart failure: Systematic review and meta-Analysis. J Am Coll Cardiol. 2006;47:1987-96.
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Gardner RS, Chong KS, O'Meara E, et al. Renal dysfunction, as measured by the modification of diet in renal disease equations, and outcome in patients with advanced heart failure. Eur Hear J. 2007;28:3027-33.
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28
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Impact of dopamine infusion on renal function in hospitalized heart failure patients: Results of the dopamine in acute decompensated heart failure (dad-hf) trial
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Small study in patients with acutely decompensated heart failure which demostrated that the combination of low-dose furosemide and low-dose dopamine (5 μgkg-1min-1 continuous infusion for 8 hours) is equally effective as high-dose furosemide but associated with improved renal function profile and potassium homeostasis
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Giamouzis G, Butler J, Starling RC, et al. Impact of dopamine infusion on renal function in hospitalized heart failure patients: Results of the dopamine in acute decompensated heart failure (DAD-HF) trial. J Card Fail. 2010;16:922-30. Small study in patients with acutely decompensated heart failure which demostrated that the combination of low-dose furosemide and low-dose dopamine (5 μgkg-1min-1 continuous infusion for 8 hours) is equally effective as high-dose furosemide but associated with improved renal function profile and potassium homeostasis.
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Evaluation of prevalence and importance of liver function test (LFT) abnormalities in a large (n02679) cohort of heart failure patients. Elevated total bilirubin was the strongest LFT predictor of adverse outcome for both the composite outcome of cardiovascular death or heart failure hospitalization and allcause mortality
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Allen LA, Felker GM, Pocock S, et al. Liver function abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure: Assessment of reduction in mortality and morbidity (charm) program. Eur J Hear Fail. 2009;11:170-7. Evaluation of prevalence and importance of liver function test (LFT) abnormalities in a large (n02679) cohort of heart failure patients. Elevated total bilirubin was the strongest LFT predictor of adverse outcome for both the composite outcome of cardiovascular death or heart failure hospitalization and allcause mortality.
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Post-hoc analysis of the placebo group of the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan) trial including patients hospitalized for systolic heart failure which demonstrated that baseline and in-hospital changes in serum albumin and total billirubin provide additional prognostic value
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Ambrosy AP, Vaduganathan M, Huffman MD, et al. Clinical course and predictive value of liver function tests in patients hospitalized for worsening heart failure with reduced ejection fraction: An analysis of the EVEREST trial. Eur J Hear Fail. 2012;14:302-11. Post-hoc analysis of the placebo group of the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan) trial including patients hospitalized for systolic heart failure which demonstrated that baseline and in-hospital changes in serum albumin and total billirubin provide additional prognostic value.
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