메뉴 건너뛰기




Volumn 180, Issue 8, 2009, Pages 692-700

Chronic obstructive pulmonary disease and obstructive sleep apnea: Overlaps in pathophysiology, systemic inflammation, and cardiovascular disease

Author keywords

Cardiovascular disease; Chronic obstructive pulmonary disease; Hypoxia; Obstructive sleep apnea; Systemic inflammation

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; C REACTIVE PROTEIN; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; THEOPHYLLINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 70349873349     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200903-0347PP     Document Type: Review
Times cited : (206)

References (96)
  • 2
    • 17844395226 scopus 로고    scopus 로고
    • There is no relationship between chronic obstructive pulmonary disease and obstructive sleep apnea syndrome: A population study
    • DOI 10.1159/000084044
    • Bednarek M, Plywaczewski R, Jonczak L, Zielinski J. There is no relationship between chronic obstructive pulmonary disease and obstructive sleep apnea syndrome: a population study. Respiration 2005;72:142-149. (Pubitemid 40591526)
    • (2005) Respiration , vol.72 , Issue.2 , pp. 142-149
    • Bednarek, M.1    Plywaczewski, R.2    Jonczak, L.3    Zielinski, J.4
  • 4
    • 39849107819 scopus 로고    scopus 로고
    • Cardiovascular morbidity in obstructive sleep apnea: Oxidative stress, inflammation, and much more
    • DOI 10.1164/rccm.200608-1190PP
    • Gozal D, Kheirandish-Gozal L. Cardiovascular morbidity in obstructive sleep apnea: oxidative stress, inflammation, and much more. Am J Respir Crit Care Med 2008;177:369-375. (Pubitemid 351317579)
    • (2008) American Journal of Respiratory and Critical Care Medicine , vol.177 , Issue.4 , pp. 369-375
    • Gozal, D.1    Kheirandish-Gozal, L.2
  • 5
    • 17644397560 scopus 로고    scopus 로고
    • Local and systemic inflammation in chronic obstructive pulmonary disease
    • DOI 10.1513/pats.200408-039MS
    • Wouters EFM. Local and systemic inflammation in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:26-33. (Pubitemid 40562960)
    • (2005) Proceedings of the American Thoracic Society , vol.2 , Issue.1 , pp. 26-33
    • Wouters, E.F.M.1
  • 6
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685-1695.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 7
    • 17644407378 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality
    • DOI 10.1513/pats.200404-032MS
    • Sin DD, Man SFP. Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality. Proc Am Thorac Soc 2005;2:8-11. (Pubitemid 40562956)
    • (2005) Proceedings of the American Thoracic Society , vol.2 , Issue.1 , pp. 8-11
    • Sin, D.D.1    Man, S.F.P.2
  • 8
    • 33846188093 scopus 로고    scopus 로고
    • Sleep apnoea as an independent risk for cardiovascular disease: Current evidence, basic mechanisms and research priorities
    • DOI 10.1183/09031936.00027406
    • McNicholas WT, Bonsignore MR. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 2007;29:156-178. (Pubitemid 46092013)
    • (2007) European Respiratory Journal , vol.29 , Issue.1 , pp. 156-178
    • McNicholas, W.T.1    Bonsignore, M.R.2
  • 9
    • 48949085757 scopus 로고    scopus 로고
    • Sleep apnea and cardiovascular disease: An American Heart Association/American College of Cardiology Foundation scientific statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing
    • Somers VK, White DP, Amin R, Abraham WT, Costa F, Culebras A, Daniels S, Floras JS, Hunt CE, Olson LJ, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation scientific statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol 2008;52:686-717.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 686-717
    • Somers, V.K.1    White, D.P.2    Amin, R.3    Abraham, W.T.4    Costa, F.5    Culebras, A.6    Daniels, S.7    Floras, J.S.8    Hunt, C.E.9    Olson, L.J.10
  • 10
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature 2000;407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 11
    • 57349184081 scopus 로고    scopus 로고
    • Cardiovascular injury and repair in chronic obstructive pulmonary disease
    • MacNee W, Maclay J, McAllister D. Cardiovascular injury and repair in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5: 824-833.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 824-833
    • MacNee, W.1    Maclay, J.2    McAllister, D.3
  • 12
    • 66749187756 scopus 로고    scopus 로고
    • Novel concepts in atherogenesis: Angiogenesis and hypoxia in atherosclerosis
    • Sluimer JC, Daemen MJ. Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis. J Pathol 2009;218:7-29.
    • (2009) J Pathol , vol.218 , pp. 7-29
    • Sluimer, J.C.1    Daemen, M.J.2
  • 20
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2007;92:347-355.
    • (2007) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 21
    • 33745021680 scopus 로고    scopus 로고
    • Systemic inflammation in COPD: Is genetic susceptibility a key factor?
    • Yanbaeva DG, Dentener MA, Creutzberg EC, Wouters EF. Systemic inflammation in COPD: is genetic susceptibility a key factor? COPD 2006;3:51-61.
    • (2006) COPD , vol.3 , pp. 51-61
    • Yanbaeva, D.G.1    Dentener, M.A.2    Creutzberg, E.C.3    Wouters, E.F.4
  • 22
    • 0034002704 scopus 로고    scopus 로고
    • Impact of sleep in COPD
    • McNicholas WT. Impact of sleep in COPD. Chest 2000;117:48S-53S.
    • (2000) Chest , vol.117
    • McNicholas, W.T.1
  • 23
    • 0021601171 scopus 로고
    • Nocturnal deaths among patients with chronic bronchitis and emphysema
    • McNicholas WT, Fitzgerald MX. Nocturnal deaths among patients with chronic bronchitis and emphysema. Br Med J (Clin Res Ed) 1984;289: 878. (Pubitemid 14006113)
    • (1984) British Medical Journal , vol.289 , Issue.6449 , pp. 878
    • McNicholas, W.T.1    Fitzgerald, M.X.2
  • 24
    • 0037316130 scopus 로고    scopus 로고
    • Obstructive sleep apnoea syndrome - An oxidative stress disorder
    • DOI 10.1053/smrv.2002.0261
    • Lavie L. Obstructive sleep apnoea syndrome: an oxidative stress disorder. Sleep Med Rev 2003;7:35-51. (Pubitemid 36188305)
    • (2003) Sleep Medicine Reviews , vol.7 , Issue.1 , pp. 35-51
    • Lavie, L.1
  • 25
    • 27444448072 scopus 로고    scopus 로고
    • Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
    • DOI 10.1161/CIRCULATIONAHA.105.556746
    • Ryan S, Taylor CT, McNicholas WT. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 2005;112:2660-2667. (Pubitemid 41532603)
    • (2005) Circulation , vol.112 , Issue.17 , pp. 2660-2667
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 26
    • 0029150565 scopus 로고
    • Pathophysiology of obstructive sleep apnoea
    • Deegan PC, McNicholas WT. Pathophysiology of obstructive sleep apnoea. Eur Respir J 1995;8:1161-1178.
    • (1995) Eur Respir J , vol.8 , pp. 1161-1178
    • Deegan, P.C.1    McNicholas, W.T.2
  • 27
    • 0023034812 scopus 로고
    • Role of diffuse airway obstruction in the hypercapnia of obstructive sleep apnea
    • Bradley TD, Rutherford R, Lue F, Moldofsky H, Grossman RF, Zamel N, Phillipson EA. Role of diffuse airway obstruction in the hypercapnia of obstructive sleep apnea. Am Rev Respir Dis 1986;134:920-924. (Pubitemid 17171646)
    • (1986) American Review of Respiratory Disease , vol.134 , Issue.5 , pp. 920-924
    • Bradley, T.D.1    Rutherford, R.2    Lue, F.3
  • 29
    • 15244344823 scopus 로고    scopus 로고
    • Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study
    • DOI 10.1016/S0140-6736(05)71141-7
    • Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-1053. (Pubitemid 40386782)
    • (2005) Lancet , vol.365 , Issue.9464 , pp. 1046-1053
    • Marin, J.M.1    Carrizo, S.J.2    Vicente, E.3    Agusti, A.G.N.4
  • 30
    • 21844465408 scopus 로고    scopus 로고
    • Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome
    • DOI 10.1378/chest.127.6.2076
    • Doherty LS, Kiely JL, Swan V, McNicholas WT. Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome. Chest 2005;127:2076-2084. (Pubitemid 46260099)
    • (2005) Chest , vol.127 , Issue.6 , pp. 2076-2084
    • Doherty, L.S.1    Kiely, J.L.2    Swan, V.3    McNicholas, W.T.4
  • 31
    • 3142517968 scopus 로고    scopus 로고
    • Association between chronic obstructive pulmonary disease and systemic inflammation: A systematic review and a meta-analysis
    • DOI 10.1136/thx.2003.019588
    • Gan WQ, Man SFP, Senthilselvan A, Sin DD. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax 2004;59:574-580. (Pubitemid 38901515)
    • (2004) Thorax , vol.59 , Issue.7 , pp. 574-580
    • Gan, W.Q.1    Man, S.F.P.2    Senthilselvan, A.3    Sin, D.D.4
  • 33
    • 34548222188 scopus 로고    scopus 로고
    • Global burden of COPD: Risk factors, prevalence, and future trends
    • Mannino DM, Buist AS. Global burden of COPD: risk factors, prevalence, and future trends. Lancet 2007;370:765-773.
    • (2007) Lancet , vol.370 , pp. 765-773
    • Mannino, D.M.1    Buist, A.S.2
  • 35
    • 0042026769 scopus 로고    scopus 로고
    • Population impact of different definitions of airway obstruction
    • DOI 10.1183/09031936.03.00075102
    • Celli BR, Halbert RJ, Isonaka S, Schau B. Population impact of different definitions of airway obstruction. Eur Respir J 2003;22:268-273. (Pubitemid 36986996)
    • (2003) European Respiratory Journal , vol.22 , Issue.2 , pp. 268-273
    • Celli, B.R.1    Halbert, R.J.2    Isonaka, S.3    Schau, B.4
  • 38
    • 0034950449 scopus 로고    scopus 로고
    • Obstructive sleep apnoea syndrome is common in subjects with chronic bronchitis: Report from the obstructive lung disease in northern Sweden studies
    • DOI 10.1159/000050506
    • Larsson LG, Lindberg A, Franklin KA, Lundbäck B. Obstructive sleep apnoea syndrome is common in subjects with chronic bronchitis: report from the Obstructive Lung Disease in Northern Sweden Studies. Respiration 2001;68:250-255. (Pubitemid 32588898)
    • (2001) Respiration , vol.68 , Issue.3 , pp. 250-255
    • Larsson, L.-G.1    Lindberg, A.2    Franklin, K.A.3    Lundback, B.4
  • 39
    • 28244460791 scopus 로고    scopus 로고
    • Systemic effects of chronic obstructive pulmonary disease
    • DOI 10.1513/pats.200504-026SR
    • Agusti AGN. Systemic effects of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:367-370. (Pubitemid 41699698)
    • (2005) Proceedings of the American Thoracic Society , vol.2 , Issue.4 , pp. 367-370
    • Agusti, A.G.N.1
  • 42
    • 0034948984 scopus 로고    scopus 로고
    • Epidemiology of chronic obstructive pulmonary disease
    • DOI 10.1183/09031936.01.17509820
    • Anto JM, Vermeire P, Vestbo J, Sunyer J. Epidemiology of chronic obstructive pulmonary disease. Eur Respir J 2001;17:982-994. (Pubitemid 32600349)
    • (2001) European Respiratory Journal , vol.17 , Issue.5 , pp. 982-994
    • Anto, J.M.1    Vermeire, P.2    Vestbo, J.3    Sunyer, J.4
  • 43
    • 0023036771 scopus 로고
    • Nocturnal hypoxaemia and quality of sleep in patients with chronic obstructive lung disease
    • Cormick W, Olson LG, Hensley MJ, Saunders NA. Nocturnal hypoxaemia and quality of sleep in patients with chronic obstructive lung disease. Thorax 1986;41:846-854. (Pubitemid 17171682)
    • (1986) Thorax , vol.41 , Issue.11 , pp. 846-854
    • Cormick, W.1    Olson, L.G.2    Hensley, M.J.3    Saunders, N.A.4
  • 44
    • 39449139631 scopus 로고    scopus 로고
    • Power spectral analysis of EEG activity during sleep in cigarette smokers
    • DOI 10.1378/chest.07-1190
    • Zhang L, Samet J, Caffo B, Bankman I, Punjabi NM. Power spectral analysis of EEG activity during sleep in cigarette smokers. Chest 2008; 133:427-432. (Pubitemid 351272401)
    • (2008) Chest , vol.133 , Issue.2 , pp. 427-432
    • Zhang, L.1    Samet, J.2    Caffo, B.3    Bankman, I.4    Punjabi, N.M.5
  • 45
    • 0023232336 scopus 로고
    • The effect of sleep loss on breathing in chronic obstructive pulmonary disease
    • Phillips BA, Cooper KR, Burke TV. The effect of sleep loss on breathing in chronic obstructive pulmonary disease. Chest 1987;91: 29-32. (Pubitemid 17215787)
    • (1987) Chest , vol.91 , Issue.1 , pp. 29-32
    • Phillips, B.A.1    Cooper, K.R.2    Burke, T.V.3
  • 46
    • 0018078013 scopus 로고
    • Control of breathing during sleep
    • Phillipson EA. Control of breathing during sleep. Am Rev Respir Dis 1978;118:909-939.
    • (1978) Am Rev Respir Dis , vol.118 , pp. 909-939
    • Phillipson, E.A.1
  • 48
    • 0030063607 scopus 로고    scopus 로고
    • Ventilation and Gas Exchenge during Sleep and exercise in Severe COPD
    • Mulloy E, McNicholas WT. Ventilation and gas exchange during sleep and exercise in severe COPD. Chest 1996;109:387-394. (Pubitemid 126422091)
    • (1996) Chest , vol.109 , Issue.2 , pp. 387-394
    • Mulloy, E.1    McNicholas, W.T.2
  • 49
    • 0021732302 scopus 로고
    • Accessory muscle activity during sleep in chronic obstructive pulmonary disease
    • Johnson MW, Remmers JE. Accessory muscle activity during sleep in chronic obstructive pulmonary disease. J Appl Physiol 1984;57:1011-1017.
    • (1984) J Appl Physiol , vol.57 , pp. 1011-1017
    • Johnson, M.W.1    Remmers, J.E.2
  • 53
    • 0027372576 scopus 로고
    • Theophylline improves gas exchange during rest, exercise, and sleep in severe chronic obstructive pulmonary disease
    • Mulloy E, McNicholas WT. Theophylline improves gas exchange during rest, exercise, and sleep in severe chronic obstructive pulmonary disease. Am Rev Respir Dis 1993;148:1030-1036. (Pubitemid 23301226)
    • (1993) American Review of Respiratory Disease , vol.148 , Issue.4 , pp. 1030-1036
    • Mulloy, E.1    McNicholas, W.T.2
  • 55
    • 79961130013 scopus 로고    scopus 로고
    • Effects of salmeterol on sleeping oxygen saturation in chronic obstructive pulmonary disease
    • E-pub ahead of print August 14, 2009
    • Ryan S, Doherty LS, Rock C, Nolan G, McNicholas WT. Effects of salmeterol on sleeping oxygen saturation in chronic obstructive pulmonary disease. Respiration 2009; E-pub ahead of print August 14, 2009.
    • (2009) Respiration
    • Ryan, S.1    Doherty, L.S.2    Rock, C.3    Nolan, G.4    McNicholas, W.T.5
  • 57
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
    • DOI 10.1056/NEJM199704033361401
    • Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-979. (Pubitemid 27152782)
    • (1997) New England Journal of Medicine , vol.336 , Issue.14 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 59
    • 26444571326 scopus 로고    scopus 로고
    • High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: The third National Health and Nutrition Examination Survey
    • DOI 10.1001/archinte.165.18.2063
    • Miller M, Zhan M, Havas S. High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey. Arch Intern Med 2005;165:2063-2068. (Pubitemid 41434580)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.18 , pp. 2063-2068
    • Miller, M.1    Zhan, M.2    Havas, S.3
  • 60
    • 33646721744 scopus 로고    scopus 로고
    • The relationship between sleep-disordered breathing and high-sensitivity C-reactive protein in Japanese men
    • Yao M, Tachibana N, Okura M, Ikeda A, Tanigawa T, Yamagishi K, Sato S, Shimamoto T, Iso H. The relationship between sleep-disordered breathing and high-sensitivity C-reactive protein in Japanese men. Sleep 2006;29:661-665. (Pubitemid 43752930)
    • (2006) Sleep , vol.29 , Issue.5 , pp. 661-665
    • Yao, M.1    Tachibana, N.2    Okura, M.3    Ikeda, A.4    Tanigawa, T.5    Yamagishi, K.6    Sato, S.7    Shimamoto, T.8    Iso, H.9
  • 61
    • 0037418181 scopus 로고    scopus 로고
    • Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure
    • DOI 10.1161/01.CIR.0000052627.99976.18
    • Yokoe T, Minoguchi K, Matsuo H, Oda N, Minoguchi H, Yoshino G, Hirano T, Adachi M. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 2003;107:1129-1134. (Pubitemid 36297204)
    • (2003) Circulation , vol.107 , Issue.8 , pp. 1129-1134
    • Yokoe, T.1    Minoguchi, K.2    Matsuo, H.3    Oda, N.4    Minoguchi, H.5    Yoshino, G.6    Hirano, T.7    Adachi, M.8
  • 62
    • 34250339549 scopus 로고    scopus 로고
    • Cardiovascular risk markers in obstructive sleep apnoea syndrome and correlation with obesity
    • DOI 10.1136/thx.2006.066720
    • Ryan S, Nolan GM, Hannigan E, Cunningham S, Taylor C, McNicholas WT. Cardiovascular risk markers in obstructive sleep apnoea syndrome and correlation with obesity. Thorax 2007;62:509-514. (Pubitemid 46910129)
    • (2007) Thorax , vol.62 , Issue.6 , pp. 509-514
    • Ryan, S.1    Nolan, G.M.2    Hannigan, E.3    Cunningham, S.4    Taylor, C.5    McNicholas, W.T.6
  • 63
    • 34547690717 scopus 로고    scopus 로고
    • Correlates of serum C-reactive protein (CRP): No association with sleep duration or sleep disordered breathing
    • Taheri S, Austin D, Lin L, Nieto FJ, Young T, Mignot E. Correlates of serum C-reactive protein (CRP): no association with sleep duration or sleep disordered breathing. Sleep 2007;30:991-996.
    • (2007) Sleep , vol.30 , pp. 991-996
    • Taheri, S.1    Austin, D.2    Lin, L.3    Nieto, F.J.4    Young, T.5    Mignot, E.6
  • 65
    • 33747600439 scopus 로고    scopus 로고
    • Systemic inflammation in patients with COPD and pulmonary hypertension
    • DOI 10.1378/chest.130.2.326
    • Joppa P, Petrasova D, Stancak B, Tkacova R. Systemic inflammation in patients with COPD and pulmonary hypertension. Chest 2006;130: 326-333. (Pubitemid 44266997)
    • (2006) Chest , vol.130 , Issue.2 , pp. 326-333
    • Joppa, P.1    Petrasova, D.2    Stancak, B.3    Tkacova, R.4
  • 66
    • 0037465734 scopus 로고    scopus 로고
    • Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? the potential role of systemic inflammation in chronic obstructive pulmonary disease
    • Sin DD, Man SFP. Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease. Circulation 2003;107:1514-1519.
    • (2003) Circulation , vol.107 , pp. 1514-1519
    • Sin, D.D.1    Man, S.F.P.2
  • 68
    • 34250362194 scopus 로고    scopus 로고
    • Systemic inflammation and decline in lung function in a general population: A prospective study
    • DOI 10.1136/thx.2006.066969
    • Fogarty AW, Jones S, Britton JR, Lewis SA, McKeever TM. Systemic inflammation and decline in lung function in a general population: a prospective study. Thorax 2007;62:515-520. (Pubitemid 46910130)
    • (2007) Thorax , vol.62 , Issue.6 , pp. 515-520
    • Fogarty, A.W.1    Jones, S.2    Britton, J.R.3    Lewis, S.A.4    McKeever, T.M.5
  • 74
    • 66749190028 scopus 로고    scopus 로고
    • Cardiovascular disease in obstructive sleep apnoea syndrome: The role of intermittent hypoxia and inflammation
    • Garvey JF, Taylor CT, McNicholas WT. Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation. Eur Respir J 2009;33:1195-1205.
    • (2009) Eur Respir J , vol.33 , pp. 1195-1205
    • Garvey, J.F.1    Taylor, C.T.2    McNicholas, W.T.3
  • 75
    • 44849100198 scopus 로고    scopus 로고
    • NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
    • DOI 10.1038/nature06905, PII NATURE06905
    • Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α. Nature 2008;453:807-811. (Pubitemid 351793778)
    • (2008) Nature , vol.453 , Issue.7196 , pp. 807-811
    • Rius, J.1    Guma, M.2    Schachtrup, C.3    Akassoglou, K.4    Zinkernagel, A.S.5    Nizet, V.6    Johnson, R.S.7    Haddad, G.G.8    Karin, M.9
  • 76
    • 2942662046 scopus 로고    scopus 로고
    • NF-κB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight
    • DOI 10.1136/thx.2003.017640
    • Agusti A, Morla M, Sauleda J, Saus C, Busquets X. NF-κB activation and i-NOS upregulation in skeletal muscle of patients with COPD and low body weight. Thorax 2004;59:483-487. (Pubitemid 38797520)
    • (2004) Thorax , vol.59 , Issue.6 , pp. 483-487
    • Agusti, A.1    Morla, M.2    Sauleda, J.3    Saus, C.4    Busquets, X.5
  • 78
    • 16844364420 scopus 로고    scopus 로고
    • Oxidative stress and airway inflammation in severe exacerbations of COPD
    • DOI 10.1136/thx.2004.027946
    • Drost EM, Skwarski KM, Sauleda J, Soler N, Roca J, Agusti A, MacNee W. Oxidative stress and airway inflammation in severe exacerbations of COPD. Thorax 2005;60:293-300. (Pubitemid 40522365)
    • (2005) Thorax , vol.60 , Issue.4 , pp. 293-300
    • Drost, E.M.1    Skwarski, K.M.2    Sauleda, J.3    Soler, N.4    Roca, J.5    Agusti, A.6    MacNee, W.7
  • 82
    • 0034034334 scopus 로고    scopus 로고
    • Oxidants/antioxidants and COPD
    • MacNee W. Oxidants/antioxidants and COPD. Chest 2000;117:303S- 317S.
    • (2000) Chest , vol.117
    • MacNee, W.1
  • 83
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95. (Pubitemid 34654215)
    • (2002) Physiological Reviews , vol.82 , Issue.1 , pp. 47-95
    • Droge, W.1
  • 86
    • 2442674412 scopus 로고    scopus 로고
    • Evidence for lipid peroxidation in obstructive sleep apnea
    • Lavie L, Vishnevsky A, Lavie P. Evidence for lipid peroxidation in obstructive sleep apnea. Sleep 2004;27:123-128. (Pubitemid 43906323)
    • (2004) Sleep , vol.27 , Issue.1 , pp. 123-128
    • Lavie, L.1    Vishnevsky, A.2    Lavie, P.3
  • 90
  • 91
    • 25444479083 scopus 로고    scopus 로고
    • Lymphocyte activation as a possible measure of atherosclerotic risk in patients with sleep apnea
    • DOI 10.1196/annals.1361.076
    • Dyugovskaya L, Lavie P, Lavie L. Lymphocyte activation as a possible measure of atherosclerotic risk in patients with sleep apnea. Ann N Y Acad Sci 2005;1051:340-350. (Pubitemid 41362764)
    • (2005) Annals of the New York Academy of Sciences , vol.1051 , pp. 340-350
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 92
    • 0036528981 scopus 로고    scopus 로고
    • Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients
    • Dyugovskaya L, Lavie P, Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 2002;165:934-939. (Pubitemid 34774660)
    • (2002) American Journal of Respiratory and Critical Care Medicine , vol.165 , Issue.7 , pp. 934-939
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 94
    • 2442461939 scopus 로고    scopus 로고
    • Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD
    • DOI 10.1378/chest.125.5.1837
    • Noguera A, Sala E, Pons AR, Iglesias J, MacNee W, Agusti AGN. Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD. Chest 2004;125:1837-1842. (Pubitemid 38648419)
    • (2004) Chest , vol.125 , Issue.5 , pp. 1837-1842
    • Noguera, A.1    Sala, E.2    Pons, A.R.3    Iglesias, J.4    MacNee, W.5    Agusti, A.G.N.6
  • 95
    • 0033956851 scopus 로고    scopus 로고
    • The activity of cytochrome oxidase is increased in circulating lymphocytes of patients with chronic obstructive pulmonary disease, asthma, and chronic arthritis
    • Sauleda J, Garcia-Palmer FJ, Gonzalez G, Palou A, Agusti AGN. The activity of cytochrome oxidase is increased in circulating lymphocytes of patients with chronic obstructive pulmonary disease, asthma, and chronic arthritis. Am J Respir Crit Care Med 2000;161:32-35. (Pubitemid 30055899)
    • (2000) American Journal of Respiratory and Critical Care Medicine , vol.161 , Issue.1 , pp. 32-35
    • Sauleda, J.1    Garcia-Palmer, F.J.2    Gonzalez, G.3    Palou, A.4    Agusti, A.G.N.5
  • 96
    • 39049084736 scopus 로고    scopus 로고
    • Diagnosis of obstructive sleep apnea in adults
    • DOI 10.1513/pats.200708-118MG
    • McNicholas WT. Diagnosis of obstructive sleep apnea in adults. Proc Am Thorac Soc 2008;5:154-160. (Pubitemid 351237873)
    • (2008) Proceedings of the American Thoracic Society , vol.5 , Issue.2 , pp. 154-160
    • McNicholas, W.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.