Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance

Journal of the American College of Cardiology

Volumn 33, Issue 4, 1999, Pages 959-965

  Adams, Volker ^a   Jiang, Hong ^a   Yu, Jiangtao ^a   Möbius Winkler, Sven ^a   Fiehn, Eduard ^a   Linke, Axel ^a   Weigl, Claudia ^a   Schuler, Gerhard ^a   Hambrecht, Rainer ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA NUCLEOTIDYLEXOTRANSFERASE; NITRIC OXIDE SYNTHASE; PROTEIN BCL 2;

ADULT; AGED; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; HEART FAILURE; HEART MUSCLE BIOPSY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; VIDEODENSITOMETRY;

ADULT; AGED; APOPTOSIS; BIOPSY; CHRONIC DISEASE; EXERCISE TEST; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL;

EID: 0033558684     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(98)00626-3     Document Type: Article

References (37)

1. Szlachcic J, Massie BM, Kramer BL, Topic N, Tubau J. Correlates and prognostic implication of exercise capacity in chronic heart failure. Am J Cardiol 1985;55:1037-42.
2. Higginbotham MB, Morris KG, Conn EH, Coleman RE, Cobb FR. Determinants of variable exercise performance among patients with severe left ventricular dysfunction. Am J Cardiol 1983;51:52-60.
3. Minotti JR, Pillay P, Oka R, Wells I, Christoph I, Massie BM. Skeletal muscle size: relationship to muscle function in heart failure. J Appl Physiol 1993;75:373-81.
4. Minotti JR, Christoph I, Oka R, Weiner MW, Wells I, Massie BM. Impaired skeletal muscle function in patients with congestive heart failure: relationship to systemic exercise performance. J Clin Invest 1991;88:2077-82.
5. Massie BM, Simonini A, Sahgal P, Wells L, Dudley GA. Relation of systemic and local muscle exercise capacity to skeletal muscle characteristics in men with congestive heart failure.) Am Coll Cardiol 1996-27:140-51.
6. Drexler H, Riede U, Münzel T, König H, Funke E, Just H. Alterations of skeletal muscle in chronic heart failure. Circulation 1992;85:1751-9.
7. Sullivan MJ, Green HJ, Cobb FR. Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure. Circulation 1990;81:518-27.
8. Massie BM, Conway M, Yonge R, et al. Skeletal muscle metabolism in patients with congestive heart failure: relation to clinical severity and blood flow. Circulation 1987;78:1009-19.
9. Ralston MA, Merola AJ, Leier CV. Depressed aerobic enzyme activity of skeletal muscle in severe chronic heart failure. J Lab Clin Med 1991;117:370-2.
10. Sullivan MJ, Green HJ, Cobb FR. Altered skeletal muscle metabolic response to exercise in chronic heart failure. Circulation 1991;84:1597-607.
11. Mallat Z, Tedgui A, Fontaliran F, Frank R, Durigon M, Fontaine G. Evidence for apoptosis in arrhythmogenic right ventricular dysplasia. N Engl J Med 1996;335:1190-6.
12. Narula J, Haider N, Virmani R, et al. Apoptosis in myocytes in end-stage heart failure. N Engl J Med 1996;335:1182-9.
13. Olivetti G, Abbi R, Quaini F, et al. Apoptosis in the failing human heart. N Engl J Med 1997;336:1131-41.
14. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1994;267:1456-62.
15. Bennett MR, Evan GI. The molecular basis of apoptosis. Heart Failure 1994;9:199-212.
16. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 1997;3:614-20.
17. Dimmeler S, Zeiher AM. Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric Oxide Biol Chem 1997;1:275-81.
18. Messmer UK, Lapetina EG, Brüne B. Nitric oxide-induced apoptosis in RAW 264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. Mol Pharmacol 1996;47:757-65.
19. Fehsel K, Kröncke KL, Meyer KL, Huber H, Wahn V, Kolb-Bachofen V. Nitric oxide induces apoptosis in mouse thymocytes. J Immunol 1995;155:2858-65.
20. Adams V, Yu J, Möbius-Winkler S, et al. Increased nitric oxide synthase in skeletal muscle biopsies from patients with chronic heart failure. Biochem Mol Med 1997;61:152-60.
21. Hambrecht R, Fiehn E, Yu J, et al. Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol 1997;29:1067-73.
22. Hambrecht R, Niebauer J, Fiehn E, et al. Effect of an acute beta-adrenergic blockade on the relationship between ventilatory and plasma lactate threshold. Int J Sports Med 1995;16: 219-24.
23. Bergström J. Muscle electrolytes in man. Scand J Clin Lab Invest 1962;68 Suppl 14:7-110.
24. Fliss H, Gattinger D. Apoptosis in ischemic and reperfused rat myocardium. Cire Res 1996;79:949-56.
25. Meltzer JC, Grimm PC, Nance DM. Enhanced immunohistochemical detection of autonomic nerve fibres, cytokine and inducible nitric oxide synthase by light and flourescent microscopy in rat spleen. J Histochem Cytochem 1997;45:599-610.
26. Togashi H, Sasaki M, Frohman E, Taira E, Ratan RR, Dawson VL. Neuronal (type I) nitric oxide synthase regulates nuclear factor kappa B activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci USA 1997;94:2676-80.
27. Cattoretti G, Pileri S, Parravicini C, et al. Antigen unmasking on formalin-fixed paraffin-embedded tissue sections. J Pathol 1993;171:83-98.
28. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 1993;262: 695-700.
29. Martinou JC, Dubois-Dauphin M, Staple JK, et al. Overexpression of bcl-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994;13:1017-30.
30. Laurent-Crawford AG, Krust B, Müller S, et al. The cytophatic effect of HIV is associated with apoptosis. Virology 1991;185:829-39.
31. Banda NK, Bernier J, Kurahara DK, et al. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med 1992;176:1099-106.
32. Steller H. Mechanisms and genes of cellular suicide. Science 1995;267:1445-9.
33. Gottlieb RA, Burleson KO, Kloner RA, Babior B, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 1994;94:1621-8.
34. Colucci WS. Apoptosis in the heart. N Engl J Med 1996;335: 1224-6.
35. Colucci WS. Molecular and cellular mechanisms of myocardial failure. Am J Cardiol 1998;80:15L-25L.
36. Iadecola C, Zhang F, Xu S, Casey R, Ross ME. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab 1995;15:378-84.
37. Förstermann U, Closs EI, Pollock JS, et al. Nitric oxide synthase isoenzymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994;23:1121-31.