Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 2, 2013, Pages

  Townsend II, Guy E ^a,b   Raghavan, Varsha ^a,c   Zwir, Igor ^a,c   Groisman, Eduardo A ^a,b,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d YALE UNIVERSITY   (United States)

Author keywords

Co evolution; Phosphorylation; Protein interactions

Indexed keywords

PROTEIN; PROTEIN KINASE; RESPONSE REGULATOR PROTEIN; SENSOR KINASE; UNCLASSIFIED DRUG;

ARTICLE; BACTEROIDES THETAIOTAOMICRON; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BACTEROIDES; BLOTTING, WESTERN; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; LIKELIHOOD FUNCTIONS; MODELS, GENETIC; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN ENGINEERING; PROTEIN KINASES; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

BACTEROIDES THETAIOTAOMICRON;

EID: 84872177104     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1212102110     Document Type: Article

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