Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics

Toxicology Letters

Volumn 217, Issue 1, 2013, Pages 1-13

  Schmeits, Peter C J ^a,b   Volger, Oscar L ^a   Zandvliet, Ella T ^a   van Loveren, Henk ^b,c   Peijnenburg, Ad A C M ^a   Hendriksen, Peter J M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

CTLL 2; Deoxynivalenol; Toxicogenomics; Transcriptomics; Tributyltin oxide

Indexed keywords

BIS(TRIBUTYLTIN) OXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; VOMITOXIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOTOXICITY; IN VITRO STUDY; LEUKEMIA CELL LINE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCREENING; T LYMPHOCYTE ACTIVATION; THYMOCYTE; TOXICITY TESTING; TRANSCRIPTOMICS;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; TECHNOLOGY, PHARMACEUTICAL; TOXICOGENETICS; TRANSCRIPTOME; TRIALKYLTIN COMPOUNDS; TRICHOTHECENES;

MURINAE;

EID: 84872149527     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.12.005     Document Type: Article

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