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Volumn 53, Issue 10, 2012, Pages 2041-2050

Involvement of miR17 pathway in glucocorticoid-induced cell death in pediatric acute lymphoblastic leukemia

Author keywords

Cell cycle and apoptosis; Changes; Chemotherapeutic approaches; Drug resistance; Lymphoid leukemia; Molecular genetics; Pharmacotherapeutics

Indexed keywords

BIM PROTEIN; DEXAMETHASONE; MICRORNA; MICRORNA 17; UNCLASSIFIED DRUG;

EID: 84865756287     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.678004     Document Type: Article
Times cited : (42)

References (42)
  • 1
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • Pui CH, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet 2008;371:1030-1043.
    • (2008) Lancet , vol.371 , pp. 1030-1043
    • Pui, C.H.1    Robison, L.L.2    Look, A.T.3
  • 2
    • 78049529488 scopus 로고    scopus 로고
    • Glucocorticoid use in acute lymphoblastic leukaemia
    • Inaba H, Pui CH. Glucocorticoid use in acute lymphoblastic leukaemia. Lancet Oncol 2010;11:1096-1106.
    • (2010) Lancet Oncol , vol.11 , pp. 1096-1106
    • Inaba, H.1    Pui, C.H.2
  • 3
    • 84873216998 scopus 로고    scopus 로고
    • General information about childhood acute lymphoblastic leukemia (ALL) [Internet]. Available from
    • General information about childhood acute lymphoblastic leukemia (ALL) [Internet]. 2011. Available from: http://www.cancer. gov/cancertopics/pdq/ treatment/childALL/HealthProfessional
    • (2011)
  • 4
    • 18144424777 scopus 로고    scopus 로고
    • Gene regulation by the glucocorticoid receptor: structure:function relationship
    • Kumar R, Thompson EB. Gene regulation by the glucocorticoid receptor: structure:function relationship. JSteroid Biochem Mol Biol 2005;94:383-394.
    • (2005) JSteroid Biochem Mol Biol , vol.94 , pp. 383-394
    • Kumar, R.1    Thompson, E.B.2
  • 5
    • 34547884315 scopus 로고    scopus 로고
    • Crosstalk between the glucocorticoid receptor and other transcription factors: Molecular aspects
    • Kassel O, Herrlich P. Crosstalk between the glucocorticoid receptor and other transcription factors: molecular aspects. Mol Cell Endocrinol 2007;275:13-29.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 13-29
    • Kassel, O.1    Herrlich, P.2
  • 6
    • 80052535611 scopus 로고    scopus 로고
    • Coactivation of grand nfkbalters the repertoire of their binding sites and target genes
    • Rao NA, McCalman MT, Moulos P, et al. Coactivation of GRand NFKBalters the repertoire of their binding sites and target genes. Genome Res 2011;21:1404-1416.
    • (2011) Genome Res , vol.21 , pp. 1404-1416
    • Rao, N.A.1    McCalman, M.T.2    Moulos, P.3
  • 7
    • 80555156759 scopus 로고    scopus 로고
    • Glucocorticoid receptormediated apoptosis: Mechanisms of resistance in cancer cells
    • Schlossmacher G, Stevens A, White A. Glucocorticoid receptormediated apoptosis: mechanisms of resistance in cancer cells. JEndocrinol 2011;211:17-25.
    • (2011) JEndocrinol , vol.211 , pp. 17-25
    • Schlossmacher, G.1    Stevens, A.2    White, A.3
  • 8
    • 39049170755 scopus 로고    scopus 로고
    • Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids
    • Miller AL, Komak S, Webb MS, et al. Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids. Cancer Cell Int 2007;7:18.
    • (2007) Cancer Cell Int , vol.7 , pp. 18
    • Miller, A.L.1    Komak, S.2    Webb, M.S.3
  • 9
    • 0038404712 scopus 로고    scopus 로고
    • Glucocorticoid regulation of human eosinophil gene expression
    • Chauhan S, Leach CH, Kunz S, et al. Glucocorticoid regulation of human eosinophil gene expression. JSteroid Biochem Mol Biol 2003;84:441-452.
    • (2003) JSteroid Biochem Mol Biol , vol.84 , pp. 441-452
    • Chauhan, S.1    Leach, C.H.2    Kunz, S.3
  • 10
    • 0035913191 scopus 로고    scopus 로고
    • Expression profiling of glucocorticoid-treated t-allcell lines: Rapid repression of multiple genes involved in rna-, protein-and nucleotide synthesis
    • Obexer P, Certa U, Kofler R, et al. Expression profiling of glucocorticoid-treated T-ALLcell lines: rapid repression of multiple genes involved in RNA-, protein-and nucleotide synthesis. Oncogene 2001;20:4324-4336.
    • (2001) Oncogene , vol.20 , pp. 4324-4336
    • Obexer, P.1    Certa, U.2    Kofler, R.3
  • 11
    • 64849103952 scopus 로고    scopus 로고
    • Glucocorticoid-regulated micrornas and mirtrons in acute lymphoblastic leukemia
    • Rainer J, Ploner C, Jesacher S, et al. Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukemia. Leukemia 2009;23:746-752.
    • (2009) Leukemia , vol.23 , pp. 746-752
    • Rainer, J.1    Ploner, C.2    Jesacher, S.3
  • 12
    • 77955593347 scopus 로고    scopus 로고
    • Microrna: A master regulator of cellular processes for bioengineering systems
    • Sun W, Julie Li YS, Huang HD, et al. microRNA: a master regulator of cellular processes for bioengineering systems. Annu Rev Biomed Eng 2010;12:1-27.
    • (2010) Annu Rev Biomed Eng , vol.12 , pp. 1-27
    • Sun, W.1    Julie Li, Y.S.2    Huang, H.D.3
  • 13
    • 34250877841 scopus 로고    scopus 로고
    • Amammalian micrornaexpression atlas based on small rnalibrary sequencing
    • Landgraf P, Rusu M, Sheridan R, et al. Amammalian microRNAexpression atlas based on small RNAlibrary sequencing. Cell 2007;129:1401-1414.
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 15
    • 77949267058 scopus 로고    scopus 로고
    • Mycn/c-myc-induced micrornas repress coding gene networks associated with poor outcome in mycn/c-myc-activated tumors
    • Mestdagh P, Fredlund E, Pattyn F, et al. MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors. Oncogene 2010;29: 1394-1404.
    • (2010) Oncogene , vol.29 , pp. 1394-1404
    • Mestdagh, P.1    Fredlund, E.2    Pattyn, F.3
  • 16
    • 77953469799 scopus 로고    scopus 로고
    • Multiple e2finduced micrornas prevent replicative stress in response to mitogenic signaling
    • Bueno MJ, Gomez de Cedron M, Laresgoiti U, et al. Multiple E2Finduced microRNAs prevent replicative stress in response to mitogenic signaling. Mol Cell Biol 2010;30:2983-2995.
    • (2010) Mol Cell Biol , vol.30 , pp. 2983-2995
    • Bueno, M.J.1    Gomez De Cedron, M.2    Laresgoiti, U.3
  • 17
    • 67349091738 scopus 로고    scopus 로고
    • The ups and downs of p53: Understanding protein dynamics in single cells
    • Batchelor E, Loewer A, Lahav G. The ups and downs of p53: understanding protein dynamics in single cells. Nat Rev Cancer 2009; 9:371-377.
    • (2009) Nat Rev Cancer , vol.9 , pp. 371-377
    • Batchelor, E.1    Loewer, A.2    Lahav, G.3
  • 18
    • 70450237022 scopus 로고    scopus 로고
    • Mechanism of chemoresistance mediated by mir-140 in human osteosarcoma and colon cancer cells
    • Song B, Wang Y, Xi Y, et al. Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene 2009;28:4065-4074.
    • (2009) Oncogene , vol.28 , pp. 4065-4074
    • Song, B.1    Wang, Y.2    Xi, Y.3
  • 19
    • 70349750196 scopus 로고    scopus 로고
    • Mir-21: An androgen receptorregulated micrornathat promotes hormone-dependent and hormone-independent prostate cancer growth
    • Ribas J, Ni X, Haffner M, et al. miR-21: an androgen receptorregulated microRNAthat promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Res 2009;69: 7165-7169.
    • (2009) Cancer Res , vol.69 , pp. 7165-7169
    • Ribas, J.1    Ni, X.2    Haffner, M.3
  • 20
    • 82855177909 scopus 로고    scopus 로고
    • Let-7 micrornas induce tamoxifen sensitivity by down-regulation of estrogen receptor alpha signaling in breast cancer
    • Zhao Y, Deng C, Lu W, et al. let-7 microRNAs induce tamoxifen sensitivity by down-regulation of estrogen receptor alpha signaling in breast cancer. Mol Med 2011;17:1233-1241.
    • (2011) Mol Med , vol.17 , pp. 1233-1241
    • Zhao, Y.1    Deng, C.2    Lu, W.3
  • 21
    • 0032506243 scopus 로고    scopus 로고
    • C-myc target gene specificity is determined by a post-dnabinding mechanism
    • Boyd KE, Wells J, Gutman J, et al. c-Myc target gene specificity is determined by a post-DNAbinding mechanism. Proc Natl Acad Sci USA1998;95:13887-13892.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13887-13892
    • Boyd, K.E.1    Wells, J.2    Gutman, J.3
  • 22
    • 67549135481 scopus 로고    scopus 로고
    • Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
    • Laane E, Tamm KP, Buentke E, et al. Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ 2009;16:1018-1029.
    • (2009) Cell Death Differ , vol.16 , pp. 1018-1029
    • Laane, E.1    Tamm, K.P.2    Buentke, E.3
  • 23
    • 36348993737 scopus 로고    scopus 로고
    • Dexamethasoneinduced apoptosis in acute lymphoblastic leukemia involves differential regulation of bcl-2 family members
    • Laane E, Panaretakis T, Pokrovskaja K, et al. Dexamethasoneinduced apoptosis in acute lymphoblastic leukemia involves differential regulation of Bcl-2 family members. Haematologica 2007; 92:1460-1469.
    • (2007) Haematologica , vol.92 , pp. 1460-1469
    • Laane, E.1    Panaretakis, T.2    Pokrovskaja, K.3
  • 24
    • 20444460289 scopus 로고    scopus 로고
    • Micrornaexpression profiles classify human cancers
    • Lu J, Getz G, Miska EA, et al. MicroRNAexpression profiles classify human cancers. Nature 2005;435:834-838.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 25
    • 77950348609 scopus 로고    scopus 로고
    • Genome-wide dissection of micrornafunctions and cotargeting networks using gene set signatures
    • Tsang JS, Ebert MS, van Oudenaarden A. Genome-wide dissection of microRNAfunctions and cotargeting networks using gene set signatures. Mol Cell 2010;38:140-153.
    • (2010) Mol Cell , vol.38 , pp. 140-153
    • Tsang, J.S.1    Ebert, M.S.2    Van Oudenaarden, A.3
  • 26
    • 20444467290 scopus 로고    scopus 로고
    • Amicrornapolycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT, et al. AmicroRNApolycistron as a potential human oncogene. Nature 2005;435:828-833.
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 27
    • 27544495514 scopus 로고    scopus 로고
    • Apolycistronic micrornacluster, mir-17-92, is overexpressed in human lung cancers andenhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, et al. Apolycistronic microRNAcluster, miR-17-92, is overexpressed in human lung cancers andenhances cell proliferation. Cancer Res 2005;65:9628-9632.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 28
    • 41949102707 scopus 로고    scopus 로고
    • Miriad roles for the mir-17-9 2 cluster in development and disease
    • Mendell JT. miRiad roles for the miR-17-9 2 cluster in development and disease. Cell 2008;133:217-222.
    • (2008) Cell , vol.133 , pp. 217-222
    • Mendell, J.T.1
  • 29
    • 73549124785 scopus 로고    scopus 로고
    • Tumorigenicity of the mir-17-92 cluster distilled
    • van Haaften G, Agami R. Tumorigenicity of the miR-17-92 cluster distilled. Genes Dev 2010;24:1-4.
    • (2010) Genes Dev , vol.24 , pp. 1-4
    • Van Haaften, G.1    Agami, R.2
  • 30
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the mir-17 through 92 family of mirnaclusters
    • Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNAclusters. Cell 2008;132:875-886.
    • (2008) Cell , vol.132 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3
  • 31
    • 58249088751 scopus 로고    scopus 로고
    • Micrornas: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 32
    • 39149095948 scopus 로고    scopus 로고
    • The bcl2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia
    • Ploner C, Rainer J, Niederegger H, et al. The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia. Leukemia 2008;22:370-377.
    • (2008) Leukemia , vol.22 , pp. 370-377
    • Ploner, C.1    Rainer, J.2    Niederegger, H.3
  • 33
    • 48249098902 scopus 로고    scopus 로고
    • Antagomir-17-5 p abolishes the growth of therapy-resistant neuroblastoma through p21 and bim.
    • Fontana L, Fiori ME, Albini S, et al. Antagomir-17-5 p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoSOne 2008;3:e2236.
    • (2008) PLoSOne , vol.3
    • Fontana, L.1    Fiori, M.E.2    Albini, S.3
  • 34
    • 78449239272 scopus 로고    scopus 로고
    • Glucocorticoids modulate micrornaexpression and processing during lymphocyte apoptosis
    • Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNAexpression and processing during lymphocyte apoptosis. JBiol Chem 2010;285:36698-36708.
    • (2010) JBiol Chem , vol.285 , pp. 36698-36708
    • Smith, L.K.1    Shah, R.R.2    Cidlowski, J.A.3
  • 35
    • 79958051537 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 beta (gsk3beta) phosphorylates the rnaase iiienzyme drosha at s300 and s302
    • Tang X, Li M, Tucker L, et al. Glycogen synthase kinase 3 beta (GSK3beta) phosphorylates the RNAase IIIenzyme Drosha at S300 and S302. PLoSOne 2011;6:e20391.
    • (2011) PLoSOne , vol.6
    • Tang, X.1    Li, M.2    Tucker, L.3
  • 36
    • 34948894886 scopus 로고    scopus 로고
    • Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum-and glucocorticoid-induced protein kinase and akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cells
    • Failor KL, Desyatnikov Y, Finger LA, et al. Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum-and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cells. Mol Endocrinol 2007;21:2403-2415.
    • (2007) Mol Endocrinol , vol.21 , pp. 2403-2415
    • Failor, K.L.1    Desyatnikov, Y.2    Finger, L.A.3
  • 37
    • 84859643687 scopus 로고    scopus 로고
    • An oncogenic role of mir-142-3p in human t-cell acute lymphoblastic leukemia (t-all) by targeting glucocorticoid receptor-alpha and camp/pkapathways
    • Lv M, Zhang X, Jia H, et al. An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-alpha and cAMP/PKApathways. Leukemia 2012;26:769-777.
    • (2012) Leukemia , vol.26 , pp. 769-777
    • Lv, M.1    Zhang, X.2    Jia, H.3
  • 38
    • 79952281614 scopus 로고    scopus 로고
    • Microrna-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
    • Rao X, Di Leva G, Li M, et al. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene 2011;30:1082-1097.
    • (2011) Oncogene , vol.30 , pp. 1082-1097
    • Rao, X.1    Di Leva, G.2    Li, M.3
  • 39
    • 77952944048 scopus 로고    scopus 로고
    • Microrna-155 regulates cell survival, growth, and chemosensitivity by targeting foxo3a in breast cancer
    • Kong W, He L, Coppola M, et al. MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. JBiol Chem 2010;285:17869-17879.
    • (2010) JBiol Chem , vol.285 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3
  • 40
    • 79952165235 scopus 로고    scopus 로고
    • Glucocorticoidmediated repression of the oncogenic micrornacluster mir-17 ~?92 contributes to the induction of bim and initiation of apoptosis
    • Molitoris JK, McColl KS, Distelhorst CW. Glucocorticoidmediated repression of the oncogenic microRNAcluster miR-17 ~?92 contributes to the induction of Bim and initiation of apoptosis. Mol Endocrinol 2011;25:409-420.
    • (2011) Mol Endocrinol , vol.25 , pp. 409-420
    • Molitoris, J.K.1    McColl, K.S.2    Distelhorst, C.W.3
  • 41
    • 80052169985 scopus 로고    scopus 로고
    • Upregulation of microrna-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia
    • Zhang H, Luo XQ, Feng DD, et al. Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia. Mol Cancer 2011;10:108.
    • (2011) Mol Cancer , vol.10 , pp. 108
    • Zhang, H.1    Luo, X.Q.2    Feng, D.D.3
  • 42
    • 33746391136 scopus 로고    scopus 로고
    • P38-mapkinase activation followed by biminduction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells
    • Lu J, Quearry B, Harada H. p38-MAPkinase activation followed by BIMinduction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells. FEBSLett 2006;580:3539-3544.
    • (2006) FEBSLett , vol.580 , pp. 3539-3544
    • Lu, J.1    Quearry, B.2    Harada, H.3


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