Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening

Toxicology and Applied Pharmacology

Volumn 226, Issue 1, 2008, Pages 46-59

  Baken, Kirsten A ^a,b   Pennings, Jeroen L A ^b   Jonker, Martijs J ^c   Schaap, Mirjam M ^b,d   de Vries, Annemieke ^b   van Steeg, Harry ^b,d   Breit, Timo M ^c   van Loveren, Henk ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Gene expression profiling; Immunotoxicogenomics; Immunotoxicology; Local lymph node assay; Toxicogenomics

Indexed keywords

BENZO[A]PYRENE; BIS(TRIBUTYLTIN) OXIDE; BRCA1 PROTEIN; CYCLOSPORIN A; GENE PRODUCT; PARACETAMOL; PROTEIN BIRC5; PROTEIN CCNA2; PROTEIN INCENP; PROTEIN P21; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL DIVISION; CONTACT SENSITIZATION; CONTROLLED STUDY; EXPOSURE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IMMUNOTOXICITY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; SCREENING; SPLEEN; TOXICOGENETICS; WEIGHT GAIN;

ACETAMINOPHEN; ANIMALS; BENZO(A)PYRENE; BODY WEIGHT; CELL CYCLE; CYCLOSPORINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNE SYSTEM; LYMPH NODES; MALE; MICE; MICE, INBRED C57BL; SPLEEN; TRIALKYLTIN COMPOUNDS;

MUS;

EID: 36849071959     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.08.026     Document Type: Article

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