Three flavonoids targeting the β-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: Crystal structure characterization with enzymatic inhibition assay

Protein Science

Volumn 17, Issue 11, 2008, Pages 1971-1978

  Zhang, Liang ^a   Kong, Yunhua ^a   Wu, Dalei ^a   Zhang, Haitao ^a   Wu, Jian ^b   Chen, Jing ^a   Ding, Jianping ^b   Hu, Lihong ^a   Jiang, Hualiang ^a   Shen, Xu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

(S) sakuranetin; Apigenin; Complex structure; HpFabz; Inhibitory mechanism; Quercetin

Indexed keywords

APIGENIN; BETA HYDROXYACYL ACYL CARRIER PROTEIN DEHYDRATASE; CARRIER PROTEIN; FLAVONOID; HYDROLYASE; QUERCETIN; SAKURANETIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HELICOBACTER PYLORI; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

APIGENIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLAVONOIDS; HELICOBACTER PYLORI; HYDRO-LYASES; PROTEIN BINDING; PROTEIN CONFORMATION; QUERCETIN;

HELICOBACTER PYLORI; HEXAPODA;

EID: 55549098939     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.036186.108     Document Type: Article

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