Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences

Journal of the American Chemical Society

Volumn 135, Issue 1, 2013, Pages 354-366

  Leu, Kevin ^a   Kervio, Eric ^c   Obermayer, Benedikt ^b   Turk Macleod, Rebecca M ^a   Yuan, Caterina ^a   Luevano, Jesus Mario ^a   Chen, Eric ^a   Gerland, Ulrich ^d   Richert, Clemens ^c   Chen, Irene A ^a,e  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF STUTTGART   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACKBONE STRUCTURES; BASE PAIRS; COOPERATIVITY; EVOLUTIONARY DYNAMICS; EVOLVABILITY; IN-SILICO; MOLECULAR EVOLUTION; MONOMER INSERTION; MUTATION RATES; NON-ENZYMATIC; ORDERS OF MAGNITUDE; POINT MUTATIONS; REPLICATION SYSTEMS; SELF-REPLICATING SYSTEM; SEQUENCE SPACE; TEMPLATE-DIRECTED SYNTHESIS;

ENZYMES; MOLECULAR BIOLOGY; RNA;

ERRORS;

IMIDAZOLE DERIVATIVE; IMIDAZOLIDE DERIVATIVE; MONOMER; NUCLEOSIDE 5' PHOSPHORIMIDAZOLIDE; OXYAZABENZOTRIAZOLIDE DERIVATIVE; PRIMER DNA; PRIMER RNA; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; DNA STRUCTURE; DNA TEMPLATE; GENE INSERTION; KINETICS; NUCLEOTIDE SEQUENCE; RNA STRUCTURE; VELOCITY;

BASE PAIR MISMATCH; BASE SEQUENCE; KINETICS; MUTATION; NUCLEIC ACIDS; OXIDATION-REDUCTION;

EID: 84872108159     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3095558     Document Type: Article

References (51)

1. Sulston, J.; Lohrmann, R.; Orgel, L. E.; Miles, H. T. Proc. Natl. Acad. Sci. U.S.A. 1968, 59, 726
2. Joyce, G. F. Cold Spring Harbor Symp. Quant. Biol. 1987, 52, 41
3. Orgel, L. Crit. Rev. Biochem. Mol. Biol. 2004, 39, 99
4. Naylor, R.; Gilham, P. T. Biochemistry 1966, 5, 2722
5. Zielinski, W. S.; Orgel, L. E. Nature 1987, 327, 346
6. Sievers, D.; von Kiedrowski, G. Nature 1994, 369, 221
7. Li, T.; Nicolaou, K. C. Nature 1994, 369, 218
8. Luther, A.; Brandsch, R.; von Kiedrowski, G. Nature 1998, 396, 245
9. Lincoln, T. A.; Joyce, G. F. Science 2009, 323, 1229
10. Woese, C.; Dugre, D.; Dugre, S.; Kondo, M.; Saxinger, W. Cold Spring Harbor Symp. Quant. Biol. 1966, 31, 723
11. Crick, F. J. Mol. Biol. 1968, 38, 367
12. Orgel, L. J. Mol. Biol. 1968, 38, 381
13. The RNA World, 3 rd ed.; Gesteland, R.; Cech, T.; Atkins, J., Eds.; Cold Spring Harbor Laboratory Press: Cold Spring Harbor, 2006.
14. Weimann, B. J.; Lohrmann, R.; Orgel, L. E.; Schneider-Bernloehr, H.; Sulston, J. E. Science 1968, 161, 387
15. Sulston, J.; Lohrmann, R.; Orgel, L. E.; Miles, H. T. Proc. Natl. Acad. Sci. U.S.A. 1968, 60, 409
16. Schrum, J. P.; Ricardo, A.; Krishnamurthy, M.; Blain, J. C.; Szostak, J. W. J. Am. Chem. Soc. 2009, 131, 14560
17. Kurz, M.; Göbel, K.; Hartel, C.; Göbel, M. W. Angew. Chem., Int. Ed. Engl. 1997, 36, 842
18. Rojas Stütz, J. A.; Richert, C. J. Am. Chem. Soc. 2001, 123, 12718
19. Kervio, E.; Hochgesand, A.; Steiner, U. E.; Richert, C. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 12074
20. Leu, K.; Obermayer, B.; Rajamani, S.; Gerland, U.; Chen, I. A. Nucleic Acids Res. 2011, 39, 8135
21. Eigen, M. Naturwissenschaften 1971, 58, 465
22. Nowak, M. A. Evolutionary Dynamics; Harvard University Press: Cambridge, MA, 2006.
23. Rajamani, S.; Ichida, J. K.; Antal, T.; Treco, D. A.; Leu, K.; Nowak, M. A.; Szostak, J. W.; Chen, I. A. J. Am. Chem. Soc. 2010, 132, 5880
24. Hagenbuch, P.; Kervio, E.; Hochgesand, A.; Plutowski, U.; Richert, C. Angew. Chem. 2005, 44, 6588
25. Lohrmann, R.; Orgel, L. E. Tetrahedron 1978, 34, 853-855
26. Bernhart, S. H.; Tafer, H.; Muckstein, U.; Flamm, C.; Stadler, P. F.; Hofacker, I. L. Algorithms Mol. Biol. 2006, 1, 3
27. Hofacker, I. L.; Fontana, W.; Stadler, P. F.; Bonhoeffer, L. S.; Tacker, M.; Schuster, P. Monatsh. Chem. 1994, 125, 167
28. Gillespie, D. J. Phys. Chem. 1977, 81, 2340
29. Sarracino, D.; Richert, C. Bioorg. Med. Chem. Lett. 1996, 6, 2543
30. Zielinski, M.; Kozlov, I. A.; Orgel, L. E. Helv. Chim. Acta 2000, 83, 1678
31. Petersen, M.; Bondensgaard, K.; Wengel, J.; Jacobsen, J. P. J. Am. Chem. Soc. 2002, 124, 5974
32. Petersen, M.; Wengel, J. Trends Biotechnol. 2003, 21, 74
33. Ferris, J. P.; Ertem, G. Science 1992, 257, 1387
34. Kawamura, K.; Maeda, J. Origins Life Evol. Biospheres 2007, 37, 153
35. Deck, C.; Jauker, M.; Richert, C. Nat. Chem. 2011, 3, 603
36. Inoue, T.; Orgel, L. E. J. Am. Chem. Soc. 1981, 103, 7666
37. Röthlingshöfer, M.; Richert, C. J. Org. Chem. 2010, 75, 3945
38. Vogel, H.; Richert, C. ChemBioChem 2012, 13, 1474
39. Prabahar, K. J.; Cole, T. D.; Ferris, J. P. J. Am. Chem. Soc. 1994, 116, 10914
40. Ichida, J. K.; Zou, K.; Horhota, A.; Yu, B.; McLaughlin, L. W.; Szostak, J. W. J. Am. Chem. Soc. 2005, 127, 2802
41. Hopfield, J. J. Proc. Natl. Acad. Sci. U.S.A. 1974, 71, 4135
42. Kanavarioti, A.; Bernasconi, C. F.; Alberas, D. J.; Baird, E. E. J. Am. Chem. Soc. 1993, 115, 8537
43. Derr, J.; Manapat, M. L.; Rajamani, S.; Leu, K.; Xulvi-Brunet, R.; Joseph, I.; Nowak, M. A.; Chen, I. A. Nucleic Acids Res. 2012, 40, 4711
44. Fontana, W.; Schuster, P. Science 1998, 280, 1451
45. Ellington, A. D.; Chen, X.; Robertson, M.; Syrett, A. Int. J. Biochem. Cell Biol. 2009, 41, 254
46. Lehman, N.; Arenas, C. D.; White, W. A.; Schmidt, F. J. Entropy 2011, 13, 17
47. Johnston, W. K.; Unrau, P. J.; Lawrence, M. S.; Glasner, M. E.; Bartel, D. P. Science 2001, 292, 1319
48. Zaher, H. S.; Unrau, P. J. RNA 2007, 13, 1017
49. Joyce, G. F. Science 2007, 315, 1507
50. Wochner, A.; Attwater, J.; Coulson, A.; Holliger, P. Science 2011, 332, 209
51. Loh, E.; Salk, J. J.; Loeb, L. A. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 1154