Redox-active protein Thioredoxin-1 administration ameliorates influenza a virus (H1N1)-induced acute lung injury in mice

Critical Care Medicine

Volumn 41, Issue 1, 2013, Pages 171-181

  Yashiro, Masato ^a   Tsukahara, Hirokazu ^a   Matsukawa, Akihiro ^a   Yamada, Mutsuko ^a   Fujii, Yosuke ^a   Nagaoka, Yoshiharu ^a   Tsuge, Mitsuru ^a   Yamashita, Nobuko ^a   Ito, Toshihiro ^a   Yamada, Masao ^a   Masutani, Hiroshi ^b   Yodoi, Junji ^b,c   Morishima, Tsuneo ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Ewha Womans University   (South Korea)

Author keywords

acute lung injury; cytokine; influenza virus; mouse; oxidative stress; thioredoxin 1

Indexed keywords

CXCL1 CHEMOKINE; MESSENGER RNA; RECOMBINANT HUMAN THIOREDOXIN 1; THIOREDOXIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; HISTOPATHOLOGY; INFLUENZA VIRUS A H1N1; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SURVIVAL RATE; VIRUS LOAD;

ACUTE LUNG INJURY; ANIMALS; ANTIOXIDANTS; CHEMOKINE CXCL1; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; PNEUMONIA, VIRAL; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS; SURVIVAL ANALYSIS; THIOREDOXINS; TUMOR NECROSIS FACTOR-ALPHA; VIRAL LOAD;

EID: 84872082870     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182676352     Document Type: Article

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