Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice

Gene Therapy

Volumn 8, Issue 19, 2001, Pages 1499-1507

  Hashiba, T ^a   Suzuki, M ^a   Nagashima, Y ^a   Suzuki, S ^a   Inoue, S ^a   Tsuburai, T ^a   Matsuse, T ^a   Ishigatubo, Y ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Adenovirus vector; Gene transfer; Influenza virus; Lung injury

Indexed keywords

BILIRUBIN; CARBON MONOXIDE; CASPASE 8; COMPLEMENTARY DNA; CYTOKINE; FERRITIN; HEAT SHOCK PROTEIN; HEME OXYGENASE;

ACUTE DISEASE; ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CLINICAL RESEARCH; CONTROLLED STUDY; DISEASE SEVERITY; DNA DAMAGE; DRUG MECHANISM; ENZYME ASSAY; EPITHELIUM CELL; FEASIBILITY STUDY; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; HEME SYNTHESIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATORY CELL; INFLUENZA VIRUS A; LOBAR PNEUMONIA; LUNG DISEASE; LUNG FIBROSIS; LUNG HEMORRHAGE; LUNG INJURY; METABOLIC REGULATION; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SURVIVAL TIME;

ADENOVIRIDAE; ANIMALS; CASPASES; DNA FRAGMENTATION; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; IN SITU NICK-END LABELING; INFLUENZA A VIRUS; LUNG; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; OXIDATIVE STRESS;

ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; INFLUENZA VIRUS; INFLUENZAVIRUS A; MURINAE;

EID: 0034782482     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301540     Document Type: Article

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