Injectable and biodegradable thermosensitive hydrogels loaded with PHBHHx nanoparticles for the sustained and controlled release of insulin

Acta Biomaterialia

Volumn 9, Issue 2, 2013, Pages 5063-5069

  Peng, Q ^a   Sun, X ^a   Gong, T ^a   Wu, C Y ^a   Zhang, T ^a   Tan, J ^a   Zhang, Z R ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Hydrogel; Insulin phospholipid complex; Nanoparticles; PHBHHx; Sustained and controlled delivery

Indexed keywords

BIOCHEMISTRY; CHITOSAN; GELS; HYDROGELS; INSULIN; NANOPARTICLES; PROTEINS;

CONTROLLED RELEASE; CONTROLLED-DELIVERY; IN-VITRO; INJECTABLES; INSULIN PHOSPHOLIPID COMPLEX; PHBHHX; POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYHEXANOATE); SUSTAINED AND CONTROLED DELIVERY; SUSTAINED RELEASE; THERMO-SENSITIVE HYDROGEL;

PHOSPHOLIPIDS;

GLUCOSE; INSULIN; NANOPARTICLE; POLY(3 HYDROXYBUTYRATE CO 3 HYDROXYHEXANOATE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; ARTICLE; BIOAVAILABILITY; BLOOD GLUCOSE MONITORING; CONTROLLED DRUG RELEASE; DRUG TRANSPORT; FREEZE DRYING; GELATION; GLUCOSE BLOOD LEVEL; HYDROGEL; IN VITRO STUDY; INSULIN RELEASE; MALE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; STORAGE;

RATTUS;

EID: 84872074701     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.09.034     Document Type: Article

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