Synthesis of potential antitubercular and antimicrobial s-triazine-based scaffolds via Suzuki cross-coupling reaction

Medicinal Chemistry Research

Volumn 22, Issue 1, 2013, Pages 367-381

  Patel, Amit B ^a   Patel, Rahul V ^a   Kumari, Premlata ^a   Rajani, Dhanji P ^b   Chikhalia, Kishor H ^c  

^a SARDAR VALLABHBHAI NATIONAL INSTITUTE OF TECHNOLOGY   (India)

^b Microcare Laboratory   (India)

^c GUJARAT UNIVERSITY   (India)

Author keywords

2,4,6 Trichloro 1,3,5 triazine: piperidine; Antimycobacterial activity; Suzuki coupling: antimicrobial activity

Indexed keywords

2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO) N (6 METHOXYBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 BROMOPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 CHLOROPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 CYANOPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 ETHOXYPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 FLUOROPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 IODOPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 METHOXYPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 NITROPHENYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (4 TOLYL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 BROMOBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 CHLOROBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 CYANOBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 ETHOXYBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 FLUOROBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 IODOBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 METHYLBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N (6 NITROBENZO[D]THIAZOL 2 YL)ACETAMIDE; 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO] N PHENYLACETAMIDE; ANTIINFECTIVE AGENT; ETHAMBUTOL; ISONIAZID; MOLECULAR SCAFFOLD; N (4 ACETAMIDOPHENYL) 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO]ACETAMIDE; N (6 ACETAMIDOBENZO[D]THIAZOL 2 YL) 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO)ACETAMIDE; N (BENZO[D]THIAZOL 2 YL) 2 [(4 (4,6 BIS(3,5 DIMETHYLPIPERIDIN 1 YL) 1,3,5 TRIAZIN 2 YL)PHENYL)AMINO]ACETAMIDE; PYRAZINAMIDE; RIFAMPICIN; TRIAZINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS CLAVATUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; BACILLUS CEREUS; BACTERIAL STRAIN; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; HYDROGEN BOND; IN VITRO STUDY; MICROCYSTIS AERUGINOSA; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; SUZUKI REACTION;

EID: 84872019463     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0041-y     Document Type: Article

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