N-{[(6-Substituted-1,3-benzothiazole-2-yl)amino]carbonothioyl}-2/4-substituted benzamides: Synthesis and pharmacological evaluation

European Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2008, Pages 1114-1122

  Rana, Arpana ^a   Siddiqui, Nadeem ^a   Khan, Suroor A ^a   Ehtaishamul Haque, Syed ^a   Bhat, Mashooq A ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Anticonvulsant; Benzamides; Benzothiazole; CNS depressant activity; Neurotoxicity

Indexed keywords

1,3 BENZOTHIAZOL 2 YL BENZAMIDE DERIVATIVE; 2 CHLORO N [[(6 METHYL 1,3 BENZOTHIAZOL 2 YL)AMINO]CARBONOTHIOYL]BENZAMIDE; BENZAMIDE DERIVATIVE; N [[(6 CHLORO 1,3 BENZOTHIAZOL 2 YL)AMINO]CARBONOTHIOYL] 4 METHOXYBENZAMIDE; N [[(6 FLUORO 1,3 BENZOTHIAZOL 2 YL)AMINO]CARBONOTHIOYL]BENZAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM DEPRESSION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EPILEPSY; IMMOBILIZATION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REACTION ANALYSIS; SPRAGUE DAWLEY RAT; STRUCTURE ANALYSIS; TOXICITY TESTING;

ANIMALS; ANTICONVULSANTS; BENZAMIDES; BENZOTHIAZOLES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; HEPATITIS, TOXIC; LIVER FUNCTION TESTS; MALE; MICE; RATS; RATS, WISTAR; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES;

EID: 42949094253     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.07.008     Document Type: Article

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