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Volumn 48, Issue 1, 2013, Pages 55-63

Age and obesity-associated changes in the expression and activation of components of the AMPK signaling pathway in human right atrial tissue

Author keywords

Adiponectin; AMPK; Human heart; Mitochondria; Obesity

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADIPONECTIN; AMP DEPENDENT PROTEIN KINASE; ELONGATION FACTOR 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE LKB1; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 84872008180     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2012.04.005     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 0025995364 scopus 로고
    • Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
    • Anderson E.A., Hoffman R.P., Balon T.W., Sinkey C.A., Mark A.L. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J. Clin. Invest. 1991, 87:2246-2252.
    • (1991) J. Clin. Invest. , vol.87 , pp. 2246-2252
    • Anderson, E.A.1    Hoffman, R.P.2    Balon, T.W.3    Sinkey, C.A.4    Mark, A.L.5
  • 4
    • 84555186814 scopus 로고    scopus 로고
    • Insulin decreases myocardial adiponectin receptor 1 expression via PI3K/Akt and FoxO1 pathway
    • Cui X.B., Wang C., Li L., Fan D., Zhou Y., Wu D., Cui Q.H., Fu F.Y., Wu L.L. Insulin decreases myocardial adiponectin receptor 1 expression via PI3K/Akt and FoxO1 pathway. Cardiovasc. Res. 2012, 93:69-78.
    • (2012) Cardiovasc. Res. , vol.93 , pp. 69-78
    • Cui, X.B.1    Wang, C.2    Li, L.3    Fan, D.4    Zhou, Y.5    Wu, D.6    Cui, Q.H.7    Fu, F.Y.8    Wu, L.L.9
  • 5
    • 0038334588 scopus 로고    scopus 로고
    • Interactions between leptin and the human sympathetic nervous system
    • Eikelis N., Schlaich M., Aggarwal A., Kaye D., Esler M. Interactions between leptin and the human sympathetic nervous system. Hypertension 2003, 41:1072-1079.
    • (2003) Hypertension , vol.41 , pp. 1072-1079
    • Eikelis, N.1    Schlaich, M.2    Aggarwal, A.3    Kaye, D.4    Esler, M.5
  • 6
    • 0029893592 scopus 로고    scopus 로고
    • Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg2+ is mediated by protein phosphatase-2A
    • Gaussin V., Hue L., Stalmans W., Bollen M. Activation of hepatic acetyl-CoA carboxylase by glutamate and Mg2+ is mediated by protein phosphatase-2A. Biochem. J. 1996, 316(Pt 1):217-224.
    • (1996) Biochem. J. , vol.316 , Issue.PART. 1 , pp. 217-224
    • Gaussin, V.1    Hue, L.2    Stalmans, W.3    Bollen, M.4
  • 7
    • 0037207099 scopus 로고    scopus 로고
    • Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: evidence for crosstalk between phosphorylation sites
    • Greif D.M., Kou R., Michel T. Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: evidence for crosstalk between phosphorylation sites. Biochemistry 2002, 41:15845-15853.
    • (2002) Biochemistry , vol.41 , pp. 15845-15853
    • Greif, D.M.1    Kou, R.2    Michel, T.3
  • 8
    • 78650385720 scopus 로고    scopus 로고
    • Effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats
    • Guo Z., Zheng C., Qin Z., Wei P. Effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats. J. Pharm. Pharmacol. 2011, 63:87-94.
    • (2011) J. Pharm. Pharmacol. , vol.63 , pp. 87-94
    • Guo, Z.1    Zheng, C.2    Qin, Z.3    Wei, P.4
  • 9
    • 10944247187 scopus 로고    scopus 로고
    • The AMP-activated protein kinase pathway-new players upstream and downstream
    • Hardie D.G. The AMP-activated protein kinase pathway-new players upstream and downstream. J. Cell Sci. 2004, 117:5479-5487.
    • (2004) J. Cell Sci. , vol.117 , pp. 5479-5487
    • Hardie, D.G.1
  • 10
    • 33644750542 scopus 로고    scopus 로고
    • AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake
    • Hutchinson D.S., Bengtsson T. AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake. Diabetes 2006, 55:682-690.
    • (2006) Diabetes , vol.55 , pp. 682-690
    • Hutchinson, D.S.1    Bengtsson, T.2
  • 11
    • 34547670934 scopus 로고    scopus 로고
    • High molecular weight adiponectin as a predictor of long-term clinical outcome in patients with coronary artery disease
    • Inoue T., Kotooka N., Morooka T., Komoda H., Uchida T., Aso Y., Inukai T., Okuno T., Node K. High molecular weight adiponectin as a predictor of long-term clinical outcome in patients with coronary artery disease. Am. J. Cardiol. 2007, 100:569-574.
    • (2007) Am. J. Cardiol. , vol.100 , pp. 569-574
    • Inoue, T.1    Kotooka, N.2    Morooka, T.3    Komoda, H.4    Uchida, T.5    Aso, Y.6    Inukai, T.7    Okuno, T.8    Node, K.9
  • 14
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki T., Yamauchi T. Adiponectin and adiponectin receptors. Endocr. Rev. 2005, 26:439-451.
    • (2005) Endocr. Rev. , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 15
    • 79956336867 scopus 로고    scopus 로고
    • Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways
    • Kang S., Chemaly E.R., Hajjar R.J., Lebeche D. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways. J. Biol. Chem. 2011, 286:18465-18473.
    • (2011) J. Biol. Chem. , vol.286 , pp. 18465-18473
    • Kang, S.1    Chemaly, E.R.2    Hajjar, R.J.3    Lebeche, D.4
  • 17
    • 34248350766 scopus 로고    scopus 로고
    • Adiponectin and the metabolic syndrome: mechanisms mediating risk for metabolic and cardiovascular disease
    • Lara-Castro C., Fu Y., Chung B.H., Garvey W.T. Adiponectin and the metabolic syndrome: mechanisms mediating risk for metabolic and cardiovascular disease. Curr. Opin. Lipidol. 2007, 18:263-270.
    • (2007) Curr. Opin. Lipidol. , vol.18 , pp. 263-270
    • Lara-Castro, C.1    Fu, Y.2    Chung, B.H.3    Garvey, W.T.4
  • 19
    • 80055110463 scopus 로고    scopus 로고
    • Effects of DPP-4 inhibition on cardiac metabolism and function in mice
    • Lenski M., Kazakov A., Marx N., Bohm M., Laufs U. Effects of DPP-4 inhibition on cardiac metabolism and function in mice. J. Mol. Cell. Cardiol. 2011, 51:906-918.
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 906-918
    • Lenski, M.1    Kazakov, A.2    Marx, N.3    Bohm, M.4    Laufs, U.5
  • 20
    • 78751529597 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation by physical activity: intact adipocytokine signaling is required
    • Li L., Pan R., Li R., Niemann B., Aurich A.C., Chen Y., Rohrbach S. Mitochondrial biogenesis and peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation by physical activity: intact adipocytokine signaling is required. Diabetes 2011, 60:157-167.
    • (2011) Diabetes , vol.60 , pp. 157-167
    • Li, L.1    Pan, R.2    Li, R.3    Niemann, B.4    Aurich, A.C.5    Chen, Y.6    Rohrbach, S.7
  • 23
  • 24
    • 33745224043 scopus 로고    scopus 로고
    • Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
    • Martin T.L., Alquier T., Asakura K., Furukawa N., Preitner F., Kahn B.B. Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J. Biol. Chem. 2006, 281:18933-18941.
    • (2006) J. Biol. Chem. , vol.281 , pp. 18933-18941
    • Martin, T.L.1    Alquier, T.2    Asakura, K.3    Furukawa, N.4    Preitner, F.5    Kahn, B.B.6
  • 26
    • 33846392950 scopus 로고    scopus 로고
    • Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
    • Mount P.F., Kemp B.E., Power D.A. Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J. Mol. Cell. Cardiol. 2007, 42:271-279.
    • (2007) J. Mol. Cell. Cardiol. , vol.42 , pp. 271-279
    • Mount, P.F.1    Kemp, B.E.2    Power, D.A.3
  • 28
    • 77958086067 scopus 로고    scopus 로고
    • Caloric restriction delays cardiac ageing in rats: role of mitochondria
    • Niemann B., Chen Y., Issa H., Silber R.E., Rohrbach S. Caloric restriction delays cardiac ageing in rats: role of mitochondria. Cardiovasc. Res. 2010, 88:267-276.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 267-276
    • Niemann, B.1    Chen, Y.2    Issa, H.3    Silber, R.E.4    Rohrbach, S.5
  • 29
    • 79251478801 scopus 로고    scopus 로고
    • Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria
    • Niemann B., Chen Y., Teschner M., Li L., Silber R.E., Rohrbach S. Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria. J. Am. Coll. Cardiol. 2011, 57:577-585.
    • (2011) J. Am. Coll. Cardiol. , vol.57 , pp. 577-585
    • Niemann, B.1    Chen, Y.2    Teschner, M.3    Li, L.4    Silber, R.E.5    Rohrbach, S.6
  • 32
    • 57449088583 scopus 로고    scopus 로고
    • Differential impact of adipokines derived from primary adipocytes of wild-type versus streptozotocin-induced diabetic rats on glucose and fatty acid metabolism in cardiomyocytes
    • Palanivel R., Vu V., Park M., Fang X., Sweeney G. Differential impact of adipokines derived from primary adipocytes of wild-type versus streptozotocin-induced diabetic rats on glucose and fatty acid metabolism in cardiomyocytes. J. Endocrinol. 2008, 199:389-397.
    • (2008) J. Endocrinol. , vol.199 , pp. 389-397
    • Palanivel, R.1    Vu, V.2    Park, M.3    Fang, X.4    Sweeney, G.5
  • 34
    • 33644850953 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
    • Poirier P., Giles T.D., Bray G.A., Hong Y., Stern J.S., Pi-Sunyer F.X., Eckel R.H. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006, 113:898-918.
    • (2006) Circulation , vol.113 , pp. 898-918
    • Poirier, P.1    Giles, T.D.2    Bray, G.A.3    Hong, Y.4    Stern, J.S.5    Pi-Sunyer, F.X.6    Eckel, R.H.7
  • 39
    • 0026569450 scopus 로고
    • Obesity, the sympathetic nervous system, and essential hypertension
    • Tuck M.L. Obesity, the sympathetic nervous system, and essential hypertension. Hypertension 1992, 19:I67-I77.
    • (1992) Hypertension , vol.19
    • Tuck, M.L.1
  • 40
    • 79952070936 scopus 로고    scopus 로고
    • Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction
    • Turdi S., Kandadi M.R., Zhao J., Huff A.F., Du M., Ren J. Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction. J. Mol. Cell. Cardiol. 2011, 50:712-722.
    • (2011) J. Mol. Cell. Cardiol. , vol.50 , pp. 712-722
    • Turdi, S.1    Kandadi, M.R.2    Zhao, J.3    Huff, A.F.4    Du, M.5    Ren, J.6
  • 41
    • 11144283125 scopus 로고    scopus 로고
    • Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone
    • Wang M.Y., Unger R.H. Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone. Am. J. Physiol. Endocrinol. Metab. 2005, 288:E216-E221.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.288
    • Wang, M.Y.1    Unger, R.H.2
  • 42
    • 78049253547 scopus 로고    scopus 로고
    • PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response
    • Wang T., Yu Q., Chen J., Deng B., Qian L., Le Y. PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response. PLoS One 2010, 5.
    • (2010) PLoS One , vol.5
    • Wang, T.1    Yu, Q.2    Chen, J.3    Deng, B.4    Qian, L.5    Le, Y.6
  • 44
    • 0035282062 scopus 로고    scopus 로고
    • Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization
    • Warden S.M., Richardson C., O'Donnell J., Stapleton D., Kemp B.E., Witters L.A. Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. Biochem. J. 2001, 354:275-283.
    • (2001) Biochem. J. , vol.354 , pp. 275-283
    • Warden, S.M.1    Richardson, C.2    O'Donnell, J.3    Stapleton, D.4    Kemp, B.E.5    Witters, L.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.