메뉴 건너뛰기




Volumn 37, Issue 1, 2013, Pages 31-39

Thromboxane Inhibitors Attenuate Inflammatory and Fibrotic Changes in Rat Liver Despite Continued Ethanol Administrations

Author keywords

Alcoholic liver disease; Fibrosis; Inflammation; NF B; Thromboxane inhibitor

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; CYCLOOXYGENASE 2; ENDOTOXIN; FISH OIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; THROMBOXANE; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; THROMBOXANE RECEPTOR BLOCKING AGENT; THROMBOXANE SYNTHASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84871999081     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2012.01838.x     Document Type: Article
Times cited : (13)

References (38)
  • 2
    • 0032217267 scopus 로고    scopus 로고
    • IkappaB-NF-kappaB structures: at the interface of inflammation control
    • Baeuerle PA (1998) IkappaB-NF-kappaB structures: at the interface of inflammation control. Cell 95:729-731.
    • (1998) Cell , vol.95 , pp. 729-731
    • Baeuerle, P.A.1
  • 3
    • 78649339034 scopus 로고    scopus 로고
    • Mechanisms and cell signaling in alcoholic liver disease
    • Beier JI, McClain CJ (2010) Mechanisms and cell signaling in alcoholic liver disease. Biol Chem 391:1249-1264.
    • (2010) Biol Chem , vol.391 , pp. 1249-1264
    • Beier, J.I.1    McClain, C.J.2
  • 4
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 5
    • 0036840372 scopus 로고    scopus 로고
    • DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells
    • Cao Q, Mak KM, Lieber CS (2002) DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 283:G1051-G1061.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Cao, Q.1    Mak, K.M.2    Lieber, C.S.3
  • 7
    • 0035036987 scopus 로고    scopus 로고
    • Ethanol consumption and liver mitochondria function
    • Cunningham CC, Bailey SM (2001) Ethanol consumption and liver mitochondria function. Biol Signals Recept 10:271-282.
    • (2001) Biol Signals Recept , vol.10 , pp. 271-282
    • Cunningham, C.C.1    Bailey, S.M.2
  • 8
    • 33749447720 scopus 로고    scopus 로고
    • Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease
    • Gobejishvili L, Barve S, Joshi-Barve S, Uriarte S, Song Z, McClain C (2006) Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 291:G681-G688.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Gobejishvili, L.1    Barve, S.2    Joshi-Barve, S.3    Uriarte, S.4    Song, Z.5    McClain, C.6
  • 10
    • 0026628848 scopus 로고
    • Eicosanoids: potential regulators of extracellular matrix formation in the kidney
    • Kohan DE (1992) Eicosanoids: potential regulators of extracellular matrix formation in the kidney. J Lab Clin Med 120:4-6.
    • (1992) J Lab Clin Med , vol.120 , pp. 4-6
    • Kohan, D.E.1
  • 11
    • 12844288099 scopus 로고    scopus 로고
    • Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis
    • Lieber CS (2004) Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. Alcohol 34:9-19.
    • (2004) Alcohol , vol.34 , pp. 9-19
    • Lieber, C.S.1
  • 12
    • 0028847434 scopus 로고
    • Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding
    • Liu SL, Degli Esposti S, Yao T, Diehl AM, Zern MA (1995) Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology 22:1474-1481.
    • (1995) Hepatology , vol.22 , pp. 1474-1481
    • Liu, S.L.1    Degli Esposti, S.2    Yao, T.3    Diehl, A.M.4    Zern, M.A.5
  • 13
    • 67349255858 scopus 로고    scopus 로고
    • Signalling pathways in alcohol-induced liver inflammation
    • Mandrekar P, Szabo G (2009) Signalling pathways in alcohol-induced liver inflammation. J Hepatol 50:1258-1266.
    • (2009) J Hepatol , vol.50 , pp. 1258-1266
    • Mandrekar, P.1    Szabo, G.2
  • 14
    • 16544371307 scopus 로고    scopus 로고
    • The epidemiology of alcoholic liver disease
    • Mann RE, Smart RG, Govoni R (2003) The epidemiology of alcoholic liver disease. Alcohol Res Health 27:209-219.
    • (2003) Alcohol Res Health , vol.27 , pp. 209-219
    • Mann, R.E.1    Smart, R.G.2    Govoni, R.3
  • 15
    • 34848876971 scopus 로고    scopus 로고
    • Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells
    • McVicker BL, Tuma DJ, Casey CA (2007) Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells. World J Gastroenterol 13:4960-4966.
    • (2007) World J Gastroenterol , vol.13 , pp. 4960-4966
    • McVicker, B.L.1    Tuma, D.J.2    Casey, C.A.3
  • 18
    • 33645987317 scopus 로고    scopus 로고
    • The isoprostanes-unique products of arachidonate peroxidation: their role as mediators of oxidant stress
    • Morrow JD (2006) The isoprostanes-unique products of arachidonate peroxidation: their role as mediators of oxidant stress. Curr Pharm Des 12:895-902.
    • (2006) Curr Pharm Des , vol.12 , pp. 895-902
    • Morrow, J.D.1
  • 19
  • 20
    • 0031022238 scopus 로고    scopus 로고
    • Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat
    • Nanji AA, Khwaja S, Rahemtulla A, Miao L, Zhao S, Tahan SR (1997a) Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. Gastroenterology 112:200-207.
    • (1997) Gastroenterology , vol.112 , pp. 200-207
    • Nanji, A.A.1    Khwaja, S.2    Rahemtulla, A.3    Miao, L.4    Zhao, S.5    Tahan, S.R.6
  • 21
    • 0028275942 scopus 로고
    • Plasma levels of a novel noncyclooxygenase-derived prostanoid (8-isoprostane) correlate with severity of liver injury in experimental alcoholic liver disease
    • Nanji AA, Khwaja S, Tahan SR, Sadrzadeh SM (1994) Plasma levels of a novel noncyclooxygenase-derived prostanoid (8-isoprostane) correlate with severity of liver injury in experimental alcoholic liver disease. J Pharmacol Exp Ther 269:1280-1285.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1280-1285
    • Nanji, A.A.1    Khwaja, S.2    Tahan, S.R.3    Sadrzadeh, S.M.4
  • 22
    • 0030981186 scopus 로고    scopus 로고
    • Cholesterol supplementation prevents necrosis and inflammation but enhances fibrosis in alcoholic liver disease in the rat
    • Nanji AA, Rahemtulla A, Daly T, Khwaja S, Miao L, Zhao S, Tahan SR (1997b) Cholesterol supplementation prevents necrosis and inflammation but enhances fibrosis in alcoholic liver disease in the rat. Hepatology 26:90-97.
    • (1997) Hepatology , vol.26 , pp. 90-97
    • Nanji, A.A.1    Rahemtulla, A.2    Daly, T.3    Khwaja, S.4    Miao, L.5    Zhao, S.6    Tahan, S.R.7
  • 23
    • 0028926255 scopus 로고
    • Role for transforming growth factor beta in thromboxane-induced increases in mesangial cell fibronectin synthesis
    • Negrete H, Studer RK, Craven PA, DeRubertis FR (1995) Role for transforming growth factor beta in thromboxane-induced increases in mesangial cell fibronectin synthesis. Diabetes 44:335-339.
    • (1995) Diabetes , vol.44 , pp. 335-339
    • Negrete, H.1    Studer, R.K.2    Craven, P.A.3    DeRubertis, F.R.4
  • 24
    • 0031577196 scopus 로고    scopus 로고
    • Evidence for the formation of F3-isoprostanes during peroxidation of eicosapentaenoic acid
    • Nourooz-Zadeh J, Halliwell B, Anggard EE (1997) Evidence for the formation of F3-isoprostanes during peroxidation of eicosapentaenoic acid. Biochem Biophys Res Commun 236:467-472.
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 467-472
    • Nourooz-Zadeh, J.1    Halliwell, B.2    Anggard, E.E.3
  • 25
    • 0027749086 scopus 로고
    • Pharmacological profile of BMS 180,291: a potent, long-acting, orally active thromboxane A2/prostaglandin endoperoxide receptor antagonist
    • Ogletree ML, Harris DN, Schumacher WA, Webb ML, Misra RN (1993) Pharmacological profile of BMS 180, 291: a potent, long-acting, orally active thromboxane A2/prostaglandin endoperoxide receptor antagonist. J Pharmacol Exp Ther 264:570-578.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 570-578
    • Ogletree, M.L.1    Harris, D.N.2    Schumacher, W.A.3    Webb, M.L.4    Misra, R.N.5
  • 27
    • 0021288839 scopus 로고
    • Spectrophotometric detection of lipid conjugated dienes
    • Recknagel RO, Glende EA Jr (1984) Spectrophotometric detection of lipid conjugated dienes. Methods Enzymol 105:331-337.
    • (1984) Methods Enzymol , vol.105 , pp. 331-337
    • Recknagel, R.O.1    Glende Jr., E.A.2
  • 28
    • 67649116613 scopus 로고    scopus 로고
    • Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    • Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J (2009) Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 373:2223-2233.
    • (2009) Lancet , vol.373 , pp. 2223-2233
    • Rehm, J.1    Mathers, C.2    Popova, S.3    Thavorncharoensap, M.4    Teerawattananon, Y.5    Patra, J.6
  • 29
    • 0034070434 scopus 로고    scopus 로고
    • Pronounced hepatic free radical formation precedes pathological liver injury in ethanol-fed rats
    • Reinke LA, Moore DR, Nanji AA (2000) Pronounced hepatic free radical formation precedes pathological liver injury in ethanol-fed rats. Alcohol Clin Exp Res 24:332-335.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 332-335
    • Reinke, L.A.1    Moore, D.R.2    Nanji, A.A.3
  • 31
    • 0034894663 scopus 로고    scopus 로고
    • Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist
    • Rosenfeld L, Grover GJ, Stier CT Jr (2001) Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist. Cardiovasc Drug Rev 19:97-115.
    • (2001) Cardiovasc Drug Rev , vol.19 , pp. 97-115
    • Rosenfeld, L.1    Grover, G.J.2    Stier Jr., C.T.3
  • 32
    • 0033625715 scopus 로고    scopus 로고
    • NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases
    • Schmid RM, Adler G (2000) NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases. Gastroenterology 118:1208-1228.
    • (2000) Gastroenterology , vol.118 , pp. 1208-1228
    • Schmid, R.M.1    Adler, G.2
  • 33
    • 0034971264 scopus 로고    scopus 로고
    • Why there are two cyclooxygenase isozymes
    • Smith WL, Langenbach R (2001) Why there are two cyclooxygenase isozymes. J Clin Invest 107:1491-1495.
    • (2001) J Clin Invest , vol.107 , pp. 1491-1495
    • Smith, W.L.1    Langenbach, R.2
  • 34
    • 61949261267 scopus 로고    scopus 로고
    • Inflammatory pathways in liver homeostasis and liver injury
    • Tacke F, Luedde T, Trautwein C (2009) Inflammatory pathways in liver homeostasis and liver injury. Clin Rev Allergy Immunol 36:4-12.
    • (2009) Clin Rev Allergy Immunol , vol.36 , pp. 4-12
    • Tacke, F.1    Luedde, T.2    Trautwein, C.3
  • 35
    • 0032185432 scopus 로고    scopus 로고
    • II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
    • Thurman RG (1998) II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol 275:G605-G611.
    • (1998) Am J Physiol , vol.275
    • Thurman, R.G.1
  • 36
    • 0033060611 scopus 로고    scopus 로고
    • Cytokine regulation of hepatic stellate cells in liver fibrosis
    • Tsukamoto H (1999) Cytokine regulation of hepatic stellate cells in liver fibrosis. Alcohol Clin Exp Res 23:911-916.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 911-916
    • Tsukamoto, H.1
  • 38
    • 23844484346 scopus 로고    scopus 로고
    • Role of thromboxane in producing hepatic injury during hepatic stress
    • Yokoyama Y, Nimura Y, Nagino M, Bland KI, Chaudry IH (2005) Role of thromboxane in producing hepatic injury during hepatic stress. Arch Surg 140:801-807.
    • (2005) Arch Surg , vol.140 , pp. 801-807
    • Yokoyama, Y.1    Nimura, Y.2    Nagino, M.3    Bland, K.I.4    Chaudry, I.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.