Independent activation of hepatitis B virus biosynthesis by retinoids, peroxisome proliferators, and bile acids

Journal of Virology

Volumn 87, Issue 2, 2013, Pages 991-997

  Reese, Vanessa C ^a   Oropeza, Claudia E ^a   Mclachlan, Alan ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CLOFIBRIC ACID; FARNESOID X RECEPTOR; HETERODIMER; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID; RETINOID X RECEPTOR ALPHA; VIRUS NUCLEOPROTEIN;

ARTICLE; CELL STRAIN HEPG2; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA SYNTHESIS; EMBRYO; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; ISOMERIZATION; LIGAND BINDING; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RNA SYNTHESIS; VIROGENESIS; VIRUS ACTIVATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

BILE ACIDS AND SALTS; CELL LINE; EPITHELIAL CELLS; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; PEROXISOME PROLIFERATORS; RETINOIDS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; VIRUS REPLICATION;

HEPATITIS B VIRUS;

EID: 84871944865     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01562-12     Document Type: Article

References (44)

1. Raney AK, McLachlan A. 1991. The biology of hepatitis B virus, p 1-37. In McLachlan A (ed), Molecular biology of the hepatitis B virus. CRC Press, Boca Raton, FL.
2. Glebe D, Urban S. 2007. Viral and cellular determinants involved in hepadnaviral entry. World J. Gastroenterol. 13:22-38.
3. Tang H, Banks KE, Anderson AL, McLachlan A. 2001. Hepatitis B virus transcription and replication. Drug News Perspect. 14:325-334.
4. Tang H, McLachlan A. 2001. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism. Proc. Natl. Acad. Sci. U. S. A. 98:1841-1846.
5. Ondracek CR, Reese VC, Rushing CN, Oropeza CE, McLachlan A. 2009. Distinct regulation of hepatitis B virus biosynthesis by peroxisome proliferator-activated receptor γ coactivator 1α and small heterodimer partner in human hepatoma cell lines. J. Virol. 83:12545-12551.
6. Ondracek CR, Rushing CN, Reese VC, Oropeza CE, McLachlan A. 2009. Peroxisome proliferator-activated receptor γ coactivator 1α and small heterodimer partner differentially regulate nuclear receptordependent hepatitis B virus biosynthesis. J. Virol. 83:12535-12544.
7. Reese VC, Ondracek CR, Rushing CN, Li L, Oropeza CE, McLachlan A. 2011. Multiple nuclear receptors may regulate hepatitis B virus biosynthesis during development. Int. J. Biochem. Cell Biol. 43:230-237.
8. Mangelsdorf DJ, Evans RM. 1995. The RXR heterodimers and orphan receptors. Cell 83:841-850.
9. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schütz G, Umesono K, Blumberg B, Kastner P, Mark M, Chambon P, Evans RM. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835-839.
10. Guidotti LG, Eggers CM, Raney AK, Chi SY, Peters JM, Gonzalez FJ, McLachlan A. 1999. In vivo regulation of hepatitis B virus replication by peroxisome proliferators. J. Virol. 73:10377-10386.
11. Reese VC, Moore DD, McLachlan A. 2012. Limited effects of bile acids and small heterodimer partner on hepatitis B virus biosynthesis in vivo. J. Virol. 86:2760-2768.
12. Xu L, Glass CK, Rosenfeld MG. 1999. Coactivator and corepressor complexes in nuclear receptor function. Curr. Opin. Genet. Dev. 9:140-147.
13. Forman BM, Umesono K, Chen J, Evans RM. 1995. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81:541-550.
14. Germain P, Iyer J, Zechel C, Gronemeyer H. 2002. Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature 415: 187-192.
15. Schulman IG, Li C, Schwabe JWR, Evans RM. 1997. The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. Genes Dev. 11:299-308.
16. Choi HS, Chung M, Tzameli I, Simha D, Lee YK, Seol W, Moore DD. 1997. Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR. J. Biol. Chem. 272:23565-23571.
17. Heyman RA, Mangelsdorf DJ, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C. 1992. 9-cis-Retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68:397-406.
18. Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterstrom RH, Perlmann T, Lehmann JM. 1998. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell 92:73-82.
19. Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, Mangelsdorf DJ. 2000. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol. Cell 6:507-515.
20. Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. 1990. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 345:224-229.
21. Muerhoff AS, Griffin KJ, Johnson EF. 1992. The peroxisome profilerator- activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid omega-hydroxylase, by clofibric acid. J. Biol. Chem. 267: 19051-19053.
22. Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ. 1995. LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev. 9:1033-1045.
23. McLachlan A, Milich DR, Raney AK, Riggs MG, Hughes JL, Sorge J, Chisari FV. 1987. Expression of hepatitis B virus surface and core antigens: Influences of pre-s and precore sequences. J. Virol. 61:683-692.
24. Raney AK, Johnson JL, Palmer CNA, McLachlan A. 1997. Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter. J. Virol. 71:1058-1071.
25. Levin AA, Sturzenbecker LJ, Kazmer S, Bosakowski T, Huselton C, Allenby G, Speck J, Kratzeisen C, Rosenberger M, Lovey A, Grippo JF. 1992. 9-cis-Retinoic acid stereoisomer binds and activates the nuclear receptor RXRαα. Nature 355:359-361.
26. Summers J, Smith PM, Huang M, Yu M. 1991. Morphogenetic and regulatory effects of mutations in the envelope proteins of an avian hepadnavirus. J. Virol. 65:1310-1317.
27. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
28. Chambon P. 1996. A decade of molecular biology of retinoic acid receptors. FASEB J. 10:940-954.
29. Durand B, Saunders M, Leroy P, Leid M, Chambon P. 1992. All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell 71:73-85.
30. Kurokawa R, Söderström M, Hörlein A, Halachmi S, Brown M, Rosenfeld MG, Glass CK. 1995. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377:451-454.
31. Kurokawa R, DiRenzo J, Boehm M, Sugarman J, Gloss B, Rosenfeld MG, Heyman RA, Glass CK. 1994. Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature 371: 528-531.
32. Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I. 2006. Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 20:2293-2305.
33. Blumberg B, Sabbagh W, Juguilon H, Bolado J, Jr, Van Meter CM, Ono ES, Evans RM. 1998. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev. 12:3195-3205.
34. Bhalla S, Ozalp C, Fang SS, Xiang LJ, Kemper K. 2004. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1α. Functional implications in hepatic cholesterol and glucose metabolism. J. Biol. Chem. 279:45139-45147.
35. Li T, Chiang JYL. 2005. Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7α-hydroxylase gene transcription. Am. J. Physiol. Gastrointest. Liver Physiol. 288:G74-G84.
36. Will H, Reiser W, Weimer T, Pfaff E, Buscher M, Sprengle R, Cattaneo R, Schaller H. 1987. Replication strategy of human hepatitis B virus. J. Virol. 61:904-911.
37. Winkler K, Weltzien P, Friedrich I, Schmitz H, Nickell HH, Hoffmann MM, Baumstark MW, Wieland H, März W. 2004. Qualitative effect of fenofibrate and quantitative effect of atorvastatin on LDL profile in combined hyperlipidemia with dense LDL. Exp. Clin. Endocrinol. Diabetes 112:241-247.
38. Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARgamma). J. Biol. Chem. 270:12953-12956.
39. Riggs BL, Hartmann LC. 2003. Selective estrogen-receptor modulators- mechanisms of action and application to clinical practice. N. Engl. J. Med. 348:618-629.
40. Huan B, Kosovsky MJ, Siddiqui A. 1995. Retinoid X receptor α transactivates the hepatitis B virus enhancer 1 element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor. J. Virol. 69:547-551.
41. Ramiere C, Scholtes C, Diaz O, Icard V, Perrin-Cocon L, Trabaud MA, Lotteau V, Andre P. 2008. Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRα. J. Virol. 82:10832-10840.
42. Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, Moore DD. 1994. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. Mol. Cell. Biol. 14:1544-1552.
43. Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Backman M, Ohlsson R, Postlind H, Blomquist P, Berkenstam A. 1998. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc. Natl. Acad. Sci. U. S. A. 95:12208-12213.
44. DiRenzo J, Söderström M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Horlein A, Rosenfeld MG, Glass CK. 1997. Peroxisome proliferator- activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol. Cell. Biol. 17:2166-2176.