메뉴 건너뛰기




Volumn 74, Issue 3-4, 2012, Pages 290-297

Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: Possible significance in ischemic brain damage

Author keywords

Brain ischemia; Glutamate; IGF 1; NMDA receptor; Tyrosine phosphorylation

Indexed keywords

6,7 DINITRO 2,3 QUINOXALINEDIONE; DIZOCILPINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

EID: 84871929557     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2012.10.001     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 34247844511 scopus 로고    scopus 로고
    • Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council. Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology
    • Adams H.P., del Zoppo G., Alberts M.J., Bhatt D.L., Brass L., Furlan A., Grubb R.L., Higashida R.T., Jauch E.C., Kidwell C., Lyden P.D., Morgenstern L.B., Qureshi A.I., Rosenwasser R.H., Scott P.A., Wijdicks E.F. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council. Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke 2007, 38:1655-1711.
    • (2007) Stroke , vol.38 , pp. 1655-1711
    • Adams, H.P.1    del Zoppo, G.2    Alberts, M.J.3    Bhatt, D.L.4    Brass, L.5    Furlan, A.6    Grubb, R.L.7    Higashida, R.T.8    Jauch, E.C.9    Kidwell, C.10    Lyden, P.D.11    Morgenstern, L.B.12    Qureshi, A.I.13    Rosenwasser, R.H.14    Scott, P.A.15    Wijdicks, E.F.16
  • 2
    • 0033906634 scopus 로고    scopus 로고
    • Structure and function of the type 1 insulin-like growth factor receptor
    • Adams T.E., Epa V.C., Garrett T.P., Ward C.W. Structure and function of the type 1 insulin-like growth factor receptor. Cell. Mol. Life Sci. 2000, 57:1050-1093.
    • (2000) Cell. Mol. Life Sci. , vol.57 , pp. 1050-1093
    • Adams, T.E.1    Epa, V.C.2    Garrett, T.P.3    Ward, C.W.4
  • 3
    • 0027085867 scopus 로고
    • Mechanisms of excitotoxicity in neurologic diseases
    • Beal M.F. Mechanisms of excitotoxicity in neurologic diseases. FASEB J. 1992, 6:3338-3344.
    • (1992) FASEB J. , vol.6 , pp. 3338-3344
    • Beal, M.F.1
  • 4
    • 0027272556 scopus 로고
    • Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1
    • Bergstedt K., Wieloch T. Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1. J. Cereb. Blood Flow Metab. 1993, 13:895-898.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 895-898
    • Bergstedt, K.1    Wieloch, T.2
  • 5
    • 0026556829 scopus 로고
    • Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II
    • Bondy C., Werner H., Roberts C.T., LeRoith D. Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II. Neuroscience 1992, 46:909-923.
    • (1992) Neuroscience , vol.46 , pp. 909-923
    • Bondy, C.1    Werner, H.2    Roberts, C.T.3    LeRoith, D.4
  • 7
    • 0036319594 scopus 로고    scopus 로고
    • P75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones
    • Bui N.T., Konig H.G., Culmsee C., Bauerbach E., Poppe M., Krieglstein J., Prehn J.H. p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones. J. Neurochem. 2002, 81:594-605.
    • (2002) J. Neurochem. , vol.81 , pp. 594-605
    • Bui, N.T.1    Konig, H.G.2    Culmsee, C.3    Bauerbach, E.4    Poppe, M.5    Krieglstein, J.6    Prehn, J.H.7
  • 9
    • 58149402202 scopus 로고    scopus 로고
    • Activating deltaPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats
    • Castaneda D., Zhao H., Mochly-Rosen D., Steinberg G.K. Activating deltaPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats. Brain Res. 2009, 1251:256-261.
    • (2009) Brain Res. , vol.1251 , pp. 256-261
    • Castaneda, D.1    Zhao, H.2    Mochly-Rosen, D.3    Steinberg, G.K.4
  • 10
    • 81355138837 scopus 로고    scopus 로고
    • Insulin-like growth factor I signaling for brain recovery and exercise ability in brain ischemic rats
    • Chang H.C., Yang Y.R., Wang P.S., Kuo C.H., Wang R.Y. Insulin-like growth factor I signaling for brain recovery and exercise ability in brain ischemic rats. Med. Sci. Sports Exerc. 2011, 43:2274-2280.
    • (2011) Med. Sci. Sports Exerc. , vol.43 , pp. 2274-2280
    • Chang, H.C.1    Yang, Y.R.2    Wang, P.S.3    Kuo, C.H.4    Wang, R.Y.5
  • 11
    • 0036319419 scopus 로고    scopus 로고
    • Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones
    • Ciani E., Virgili M., Contestabile A. Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones. J. Neurochem. 2002, 81:218-228.
    • (2002) J. Neurochem. , vol.81 , pp. 218-228
    • Ciani, E.1    Virgili, M.2    Contestabile, A.3
  • 13
    • 0030717725 scopus 로고    scopus 로고
    • Insulin-like growth factors regulate neuronal differentiation and survival
    • Feldman E.L., Sullivan K.A., Kim B., Russell J.W. Insulin-like growth factors regulate neuronal differentiation and survival. Neurobiol. Dis. 1997, 4:201-214.
    • (1997) Neurobiol. Dis. , vol.4 , pp. 201-214
    • Feldman, E.L.1    Sullivan, K.A.2    Kim, B.3    Russell, J.W.4
  • 14
    • 67650848390 scopus 로고    scopus 로고
    • Intranasal delivery of erythropoietin plus insulin-like growth factor-I for acute neuroprotection in stroke. Laboratory investigation
    • Fletcher L., Kohli S., Sprague S.M., Scranton R.A., Lipton S.A., Parra A., Jimenez D.F., Digicaylioglu M. Intranasal delivery of erythropoietin plus insulin-like growth factor-I for acute neuroprotection in stroke. Laboratory investigation. J. Neurosurg. 2009, 111:164-170.
    • (2009) J. Neurosurg. , vol.111 , pp. 164-170
    • Fletcher, L.1    Kohli, S.2    Sprague, S.M.3    Scranton, R.A.4    Lipton, S.A.5    Parra, A.6    Jimenez, D.F.7    Digicaylioglu, M.8
  • 15
    • 0346494287 scopus 로고    scopus 로고
    • Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling
    • Garcia-Galloway E., Arango C., Pons S., Torres-Aleman I. Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling. Mol. Cell. Neurosci. 2003, 24:1027-1037.
    • (2003) Mol. Cell. Neurosci. , vol.24 , pp. 1027-1037
    • Garcia-Galloway, E.1    Arango, C.2    Pons, S.3    Torres-Aleman, I.4
  • 16
    • 0025514134 scopus 로고
    • Ischemia induces release of glutamate in regions spared from histopathologic damage in the rat
    • Globus M.Y., Busto R., Martinez E., Valdes I., Dietrich W.D. Ischemia induces release of glutamate in regions spared from histopathologic damage in the rat. Stroke 1990, 21:III43-III46.
    • (1990) Stroke , vol.21 , pp. 43-46
    • Globus, M.Y.1    Busto, R.2    Martinez, E.3    Valdes, I.4    Dietrich, W.D.5
  • 17
    • 38349177105 scopus 로고    scopus 로고
    • Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model
    • Ha S.K., Lee P., Park J.A., Oh H.R., Lee S.Y., Park J.H., Lee E.H., Ryu J.H., Lee K.R., Kim S.Y. Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model. Neurochem. Int. 2008, 52:878-886.
    • (2008) Neurochem. Int. , vol.52 , pp. 878-886
    • Ha, S.K.1    Lee, P.2    Park, J.A.3    Oh, H.R.4    Lee, S.Y.5    Park, J.H.6    Lee, E.H.7    Ryu, J.H.8    Lee, K.R.9    Kim, S.Y.10
  • 18
    • 29044449313 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: a revolving neurochemical axis for therapeutic intervention?
    • Haddad J.J. N-methyl-D-aspartate (NMDA) and the regulation of mitogen-activated protein kinase (MAPK) signaling pathways: a revolving neurochemical axis for therapeutic intervention?. Prog. Neurobiol. 2005, 77:252-282.
    • (2005) Prog. Neurobiol. , vol.77 , pp. 252-282
    • Haddad, J.J.1
  • 19
    • 0141676771 scopus 로고    scopus 로고
    • Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
    • Ikonomidou C., Turski L. Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?. Lancet Neurol. 2002, 1:383-386.
    • (2002) Lancet Neurol. , vol.1 , pp. 383-386
    • Ikonomidou, C.1    Turski, L.2
  • 20
    • 0033951989 scopus 로고    scopus 로고
    • Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons
    • Jiang Q., Gu Z., Zhang G., Jing G. Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons. Brain Res. 2000, 857:71-77.
    • (2000) Brain Res. , vol.857 , pp. 71-77
    • Jiang, Q.1    Gu, Z.2    Zhang, G.3    Jing, G.4
  • 21
    • 28744455284 scopus 로고    scopus 로고
    • Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways
    • Kilic E., Kilic U., Soliz J., Bassetti C.L., Gassmann M., Hermann D.M. Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J. 2005, 19:2026-2028.
    • (2005) FASEB J. , vol.19 , pp. 2026-2028
    • Kilic, E.1    Kilic, U.2    Soliz, J.3    Bassetti, C.L.4    Gassmann, M.5    Hermann, D.M.6
  • 22
    • 65249096594 scopus 로고    scopus 로고
    • Insulin-like growth factor I: a potential neuroprotective compound for the treatment of acute ischemic stroke?
    • Kooijman R., Sarre S., Michotte Y., De Keyser J. Insulin-like growth factor I: a potential neuroprotective compound for the treatment of acute ischemic stroke?. Stroke 2009, 40:e83-e88.
    • (2009) Stroke , vol.40
    • Kooijman, R.1    Sarre, S.2    Michotte, Y.3    De Keyser, J.4
  • 24
    • 0035976728 scopus 로고    scopus 로고
    • Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons
    • Kumari S., Liu X., Nguyen T., Zhang X., D'Mello S.R. Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons. Brain Res. Mol. Brain Res. 2001, 96:157-162.
    • (2001) Brain Res. Mol. Brain Res. , vol.96 , pp. 157-162
    • Kumari, S.1    Liu, X.2    Nguyen, T.3    Zhang, X.4    D'Mello, S.R.5
  • 25
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D., Werner H., Beitner-Johnson D., Roberts C.T. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 1995, 16:143-163.
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts, C.T.4
  • 26
    • 0035875455 scopus 로고    scopus 로고
    • Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage
    • Liu X.F., Fawcett J.R., Thorne R.G., DeFor T.A., Frey W.H. Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage. J. Neurol. Sci. 2001, 187:91-97.
    • (2001) J. Neurol. Sci. , vol.187 , pp. 91-97
    • Liu, X.F.1    Fawcett, J.R.2    Thorne, R.G.3    DeFor, T.A.4    Frey, W.H.5
  • 27
    • 0141925703 scopus 로고    scopus 로고
    • Neuroprotective effects of insulin-like growth factor-binding protein ligand inhibitors in vitro and in vivo
    • Mackay K.B., Loddick S.A., Naeve G.S., Vana A.M., Verge G.M., Foster A.C. Neuroprotective effects of insulin-like growth factor-binding protein ligand inhibitors in vitro and in vivo. J. Cereb. Blood Flow Metab. 2003, 23:1160-1167.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1160-1167
    • Mackay, K.B.1    Loddick, S.A.2    Naeve, G.S.3    Vana, A.M.4    Verge, G.M.5    Foster, A.C.6
  • 28
    • 34249092704 scopus 로고    scopus 로고
    • Calcium and neurodegeneration
    • Mattson M.P. Calcium and neurodegeneration. Aging Cell 2007, 6:337-350.
    • (2007) Aging Cell , vol.6 , pp. 337-350
    • Mattson, M.P.1
  • 29
    • 0035194849 scopus 로고    scopus 로고
    • Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice
    • Noshita N., Lewen A., Sugawara T., Chan P.H. Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 2001, 21:1442-1450.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 1442-1450
    • Noshita, N.1    Lewen, A.2    Sugawara, T.3    Chan, P.H.4
  • 30
    • 0025260736 scopus 로고
    • Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage
    • Pellegrini-Giampietro D.E., Cherici G., Alesiani M., Carla V., Moroni F. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 1990, 10:1035-1041.
    • (1990) J. Neurosci. , vol.10 , pp. 1035-1041
    • Pellegrini-Giampietro, D.E.1    Cherici, G.2    Alesiani, M.3    Carla, V.4    Moroni, F.5
  • 31
    • 41549156954 scopus 로고    scopus 로고
    • PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease
    • Quesada A., Lee B.Y., Micevych P.E. PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. Dev. Neurobiol. 2008, 68:632-644.
    • (2008) Dev. Neurobiol. , vol.68 , pp. 632-644
    • Quesada, A.1    Lee, B.Y.2    Micevych, P.E.3
  • 32
    • 0030561276 scopus 로고    scopus 로고
    • Mechanism of glutamate release from rat hippocampal slices during in vitro ischemia
    • Roettger V., Lipton P. Mechanism of glutamate release from rat hippocampal slices during in vitro ischemia. Neuroscience 1996, 75:677-685.
    • (1996) Neuroscience , vol.75 , pp. 677-685
    • Roettger, V.1    Lipton, P.2
  • 33
    • 13444292906 scopus 로고    scopus 로고
    • Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity
    • Rusanescu G., Yang W., Bai A., Neel B.G., Feig L.A. Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity. EMBO J. 2005, 24:305-314.
    • (2005) EMBO J. , vol.24 , pp. 305-314
    • Rusanescu, G.1    Yang, W.2    Bai, A.3    Neel, B.G.4    Feig, L.A.5
  • 34
    • 45549105772 scopus 로고    scopus 로고
    • Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke
    • Sawe N., Steinberg G., Zhao H. Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke. J. Neurosci. Res. 2008, 86:1659-1669.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1659-1669
    • Sawe, N.1    Steinberg, G.2    Zhao, H.3
  • 35
    • 77952626873 scopus 로고    scopus 로고
    • The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-dependent loss of insulin-like growth factor-1
    • Selvamani A., Sohrabji F. The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-dependent loss of insulin-like growth factor-1. J. Neurosci. 2010, 30:6852-6861.
    • (2010) J. Neurosci. , vol.30 , pp. 6852-6861
    • Selvamani, A.1    Sohrabji, F.2
  • 37
    • 2942695980 scopus 로고    scopus 로고
    • IGF-I prevents glutamate-induced motor neuron programmed cell death
    • Vincent A.M., Mobley B.C., Hiller A., Feldman E.L. IGF-I prevents glutamate-induced motor neuron programmed cell death. Neurobiol. Dis. 2004, 16:407-416.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 407-416
    • Vincent, A.M.1    Mobley, B.C.2    Hiller, A.3    Feldman, E.L.4
  • 38
    • 0036884489 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes
    • Walsh P.T., Smith L.M., O'Connor R. Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes. Immunology 2002, 107:461-471.
    • (2002) Immunology , vol.107 , pp. 461-471
    • Walsh, P.T.1    Smith, L.M.2    O'Connor, R.3
  • 39
    • 0034708696 scopus 로고    scopus 로고
    • Reduction of ischemic brain injury by topical application of insulin-like growth factor-I after transient middle cerebral artery occlusion in rats
    • Wang J.M., Hayashi T., Zhang W.R., Sakai K., Shiro Y., Abe K. Reduction of ischemic brain injury by topical application of insulin-like growth factor-I after transient middle cerebral artery occlusion in rats. Brain Res. 2000, 859:381-385.
    • (2000) Brain Res. , vol.859 , pp. 381-385
    • Wang, J.M.1    Hayashi, T.2    Zhang, W.R.3    Sakai, K.4    Shiro, Y.5    Abe, K.6
  • 40
    • 33847014888 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke
    • Zhao H., Sapolsky R.M., Steinberg G.K. Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke. Mol. Neurobiol. 2006, 34:249-270.
    • (2006) Mol. Neurobiol. , vol.34 , pp. 249-270
    • Zhao, H.1    Sapolsky, R.M.2    Steinberg, G.K.3
  • 42
    • 0036328592 scopus 로고    scopus 로고
    • FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling
    • Zheng W.H., Kar S., Quirion R. FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling. J. Neurochem. 2002, 80:1049-1061.
    • (2002) J. Neurochem. , vol.80 , pp. 1049-1061
    • Zheng, W.H.1    Kar, S.2    Quirion, R.3
  • 43
    • 0036078618 scopus 로고    scopus 로고
    • Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons
    • Zheng W.H., Kar S., Quirion R. Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons. Mol. Pharmacol. 2002, 62:225-233.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 225-233
    • Zheng, W.H.1    Kar, S.2    Quirion, R.3
  • 44
    • 2542473205 scopus 로고    scopus 로고
    • Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival
    • Zheng W.H., Quirion R. Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival. J. Neurochem. 2004, 89:844-852.
    • (2004) J. Neurochem. , vol.89 , pp. 844-852
    • Zheng, W.H.1    Quirion, R.2
  • 45
    • 59449095272 scopus 로고    scopus 로고
    • Glutamate acting on N-methyl-d-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and its survival signaling properties in rat hippocampal neurons
    • Zheng W.H., Quirion R. Glutamate acting on N-methyl-d-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and its survival signaling properties in rat hippocampal neurons. J. Biol. Chem. 2009, 284:855-861.
    • (2009) J. Biol. Chem. , vol.284 , pp. 855-861
    • Zheng, W.H.1    Quirion, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.