Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis

Science

Volumn 339, Issue 6115, 2013, Pages 88-91

  Chakraborty, Sumit ^a   Gruber, Todd ^b   Barry III, Clifton E ^b   Boshoff, Helena I ^b   Rhee, Kyu Y ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; AMINOSALICYLIC ACID; DIHYDROPTEROATE SYNTHASE;

BACTERIUM; DRUG; ENZYME ACTIVITY; GROWTH RATE; INHIBITOR; ORGANIC ACID; SUBSTRATE; TUBERCULOSIS;

ARTICLE; BACTERIAL GROWTH; CELL METABOLISM; ENZYME INHIBITION; FOLATE METABOLISM; GROWTH INHIBITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84871927537     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1228980     Document Type: Article

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