Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli

ACS Chemical Biology

Volumn 5, Issue 8, 2010, Pages 787-795

  Kwon, Yun Kyung ^a   Higgins, Meytal B ^a   Rabinowitz, Joshua D ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; GLYCINE; PURINE DERIVATIVE; THYMINE; TRIMETHOPRIM;

ARTICLE; BACTERIAL GROWTH; CELL FATE; CELL LEVEL; CULTURE MEDIUM; DRUG MECHANISM; ESCHERICHIA COLI; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; FOLIC ACID ANTAGONISTS; GLYCINE; METABOLOME; PURINES; THYMINE; TRIMETHOPRIM;

EID: 77955867163     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100096f     Document Type: Article

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